Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Etoposide Methotrexate

Doxorubin Etoposide Methotrexate Mitoxantrone Cisplatin Vincristine Vinblastine Iiinotecan ... [Pg.45]

Carcinoma of testis Combination chemotherapy cisplatin, bleomycin, and etoposide Methotrexate, dactinomycin, plicamycin, vinblastine, doxorubicin, cyclophosphamide, etoposide, ifosfamide plus mesna1... [Pg.1311]

Change in sensitivity (or T level) or 4 binding affinity of target enzymes or receptors Etoposide, methotrexate, vinca alkaloids, estrogen and androgen receptors... [Pg.293]

Chemotherapeutic agents for neoplastic diseases Adriamycin Bleomycin Daunomycin Etoposide Methotrexate... [Pg.287]

MRPl ABGGl Vincristine Doxorubicin Etoposide methotrexate Organic anions Glutathione conjugated-doxorubicin, melphalan, aflatoxin B1 Gluthathione... [Pg.370]

ABCCl MRPl Camptothecins, colchicine, daunorubicin, doxorubicin, etoposide, methotrexate, paclitaxel, vincristine, vinblastine... [Pg.124]

Doxorubicin and cyclophosphamide have no clinically relevant effects on the pharmacokinetics of oral or intravenous etoposide. Methotrexate and procarbazine do not affect the pharmacokinetics of oral etoposide. [Pg.631]

MANAGING ALOPECIA. Alopecia (loss of hair) is a common adverse reaction associated with some of the antineoplastic drugs. Some drugs cause severe hair loss, whereas others cause gradual thinning. Examples of drug commonly associated with severe hair loss are doxorubicin and vinblastine Methotrexate, bleomycin, vincristine, and etoposide are associated with gradual hair loss. [Pg.597]

DOX, doxorubicine TAX, taxol MTX, methotrexate DDPt, cisplatin 5PU, flurouracil ETO, etoposide. [Pg.368]

The rapidly proliferating cells of the GI tract make them susceptible to the effects of chemotherapy. Mucositis is the inflamed, ulcerated mucosa of the mouth, esophagus, and lower GI tract that may result in infection and pain with subsequent decreased fluid and nutritional intake. Methotrexate, 5-FU, etoposide, and doxorubicin are the chemotherapy agents most commonly associated with mucositis. Patients should be instructed on good oral mouth care and use saline rinses several... [Pg.1298]

Anticancer drugs Methotrexate Doxorubicin Daunorubicin Epirubicin Etoposide Vincristine Vinblastine Paclitaxel Iiinotecan... [Pg.44]

ADRIAMYCIN ETOPOSIDE TENIPOSIDE TOPOTECAN AMSACRINE 5-FLUOROURACIL METHOTREXATE HYDROXYUREA PALA... [Pg.4]

CAV = cyclophosphamide/doxorubicin/vincristine CEV = cyclophosphamide/epirubicin/vincristine CCM = cyclophosphamide/lomustine/methotrexate EA = etoposide/doxorubicin VMV/VAC = vincristine, methotrexate, VP-16/vincristine, doxorubicin, cyclophosphamide VAP = vincristine/doxorubicin/ procarbazine PE = cisplatin/etoposide. [Pg.199]

Metastatic osteosarcoma has a poor prognosis unless the disease is confined to the lungs and is resectable. Palliative chemotherapy can be employed with a number of drugs including doxorubicin, cisplatin, carboplatin, methotrexate, ifosfamide and etoposide. [Pg.720]

Acute myelocytic and myelomonocytic leukemia Combination chemotherapy cytarabine and mitoxantrone or daunorubicin or idarubicin Methotrexate, thioguanine, mercaptopurine, allopurinol,1 mitoxantrone, azacitidine,2 amsacrine,2 etoposide... [Pg.1310]

Choriocarcinoma (trophoblastic neoplasms) Methotrexate alone or etoposide and cisplatin Vinblastine, mercaptopurine, chlorambucil, doxorubicin... [Pg.1312]

Drugs used in cancer chemotherapy are cytotoxic drugs, hormones, plant derivatives, radioactive isotopes, and miscellaneous agents (e.g., procarbazine, hydroxyurea, mitotane). The plant-based drugs vincristine, vinblastine, vinorel-bine, etoposide, and campothecins. Radioactive isotopes, such as 131 iodine (131 I), are used in the treatment of thyroid tumors. Cytotoxic drugs (e.g., cis-platin, cyclophosphamide, 6-mercaptopurine, 5-fluorouracil, and methotrexate are used for the treatment of cancer. [Pg.287]

Sulfuric acid and potassium permanganate are used to dispose of doxorubicin or daunorubicin wastes. Doxorubicin shows mutagenicity only at high concentrations. Care must be exercised by wearing protective clothing when handling urine and feces after administration of doxorubicin, etoposides, fluorouracil, methotrexate, mitoxantrone, mustine, procarbazine, melphalan, mercaptopurine, vinblastine, vincristine, and hydroxyurea.217... [Pg.361]

Fig. 3 Venn-diagram for selected compounds interacting with the key MDR-related ABC transporters. MDR-substrate anticancer agents. Abbreviations VCR vincristine, VP-16 etoposide, STER steroids, TAM tamoxiphen, TKI-INHIB tyrosin kinase inhibitors e.g. STI-571, DOX doxorubicine or adriamycin, DNR daunorubicin, EPIR epirubicin, MX mitoxantrone, TOPOT topotecan, iridotecan, BISANT bisanthrone, COLCH colchicin, ACT-D actinomycin D, MYTOM mytomycin, TX methotrexate, CPHAM cyclophosphamide, CHLB chlorambucil, CARM carmustine, LCV leucovorin, HUR hydroxy urea, CISPL cisplatin, TAXOL paclitaxel. (Reproduced from [4])... Fig. 3 Venn-diagram for selected compounds interacting with the key MDR-related ABC transporters. MDR-substrate anticancer agents. Abbreviations VCR vincristine, VP-16 etoposide, STER steroids, TAM tamoxiphen, TKI-INHIB tyrosin kinase inhibitors e.g. STI-571, DOX doxorubicine or adriamycin, DNR daunorubicin, EPIR epirubicin, MX mitoxantrone, TOPOT topotecan, iridotecan, BISANT bisanthrone, COLCH colchicin, ACT-D actinomycin D, MYTOM mytomycin, TX methotrexate, CPHAM cyclophosphamide, CHLB chlorambucil, CARM carmustine, LCV leucovorin, HUR hydroxy urea, CISPL cisplatin, TAXOL paclitaxel. (Reproduced from [4])...
Docetaxel Etoposide Eluorouracil Gemcitabine Methotrexate Mitomycin Mitoxantrone Paclitaxel Pemetrexed Topotecan Trastuzumab Bevacizumab Bleomycin Busulfan... [Pg.296]

Endometrial Ewing s sarcomao" Gastric Head and neck,squamous cell Islet cell (pancreas) Kaposi s sarcoma Doxorubicin cisplatin + cyclophosphamide CAV Cyclophosphamide (or Ifosfamide) + doxorubicin (Adriamycin) + vincristine CF epirubidri + cisplatin 5-fluorouraci1 Cisplatin + S-fluorouracil Methotrexate Screptozotocin + S-fluorouracil Etoposide or interferon affa or vinblastine ABV doxorubicin (Adriamycin) + bteomycin + vincristine or vinblastine... [Pg.607]

Five of thirty-two patients treated with the alternating drug regimen CAMBO-VIP (cyclophosphamide, doxorubicin, methotrexate, bleomycin, vincristine, etoposide, ifosfamide, and prednisolone) for non-Hodgkin s lymphoma developed blisters under the thickened skin of the palms and/or soles, followed by desquamation (28). [Pg.1027]

A 55-year-old man with chronic lymphocytic leukemia and rheumatoid arthritis took methotrexate for 4 years and developed a B cell non-Hodgkin s lymphoma in the shoulder and axillary lymph nodes he had Epstein-Barr viral antigens in the serum. After radiation and chemotherapy had failed, complete remission was achieved with a combination of rituximab and EPOCH (etoposide -I- prednisone -I- vincristine -I-cyclophosphamide + doxorubicin). [Pg.2284]

Clinically important, potentially hazardous interactions with altretamine, amikacin, aminoglycosides, antineoplastics, bleomycin, busulfan, carboplatin, carmustine, chlorambucil, cisplatin, corticosteroids, cyclophosphamide, cytarabine, dacarbazine, dactinomycin, daunorubicin, docetaxel, doxorubicin, estramustine, etoposide, fludarabine, fluorouracil, gemcitabine, gentamicin, hydroxyurea, idarubicin, ifosfamide, indomethacin, kanamycin, levamisole, lomustine, mechlorethamine, melphalan, mercaptopurine, methotrexate, mitomycin, mitotane, mitoxantrone, neomycin, pentostatin, plicamycin, procarbazine, streptomycin, streptozocin, thioguanine, thiotepa, tobramycin, tretinoin, uracil, vinblastine, vincristine, vinorelbine... [Pg.13]

Clinically important, potentially hazardous interactions with aluminum, aminophylline, carbamazepine, carbimazole, cyclosporine, daclizumab, diuretics, etoposide, etretinate, grapefruit juice, indomethacin, isoniazid, itraconazole, ketoconazole, licorice, live vaccines, methotrexate, naproxen, oral contraceptives, pancuronium, phenobarbital, phenytoin, rifampicin, troleandomycin... [Pg.473]

Two diorganotin(IV) salicyloxamate derivatives (Figure 4.4.17), containing a tetracoordinate tin, have been reported to possess high potency compared with cisplatin, 5-fluorouracil, and etoposide against several human tnmor cell lines, but less active than methotrexate and doxorubicin. ... [Pg.463]

See other pages where Etoposide Methotrexate is mentioned: [Pg.2378]    [Pg.2453]    [Pg.37]    [Pg.309]    [Pg.124]    [Pg.124]    [Pg.208]    [Pg.2378]    [Pg.2453]    [Pg.37]    [Pg.309]    [Pg.124]    [Pg.124]    [Pg.208]    [Pg.751]    [Pg.367]    [Pg.1381]    [Pg.194]    [Pg.381]    [Pg.456]    [Pg.1321]    [Pg.129]    [Pg.751]    [Pg.243]    [Pg.392]    [Pg.30]    [Pg.1543]    [Pg.2863]    [Pg.303]   
See also in sourсe #XX -- [ Pg.631 ]



SEARCH



Etoposide

Methotrexate

© 2024 chempedia.info