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Methotrexate Cisplatin

Harker WG, Meyers FJ, Freiha FS, et al. Cisplatin, methotrexate, and vinblastine (CMV) an effective chemotherapy regimen for metastatic transitional cell carcinoma of the urinary tract a Northern California Oncology Group study. J Clin Oncol 1985 3 1463-1470. [Pg.300]

Medical Research Council Advanced Bladder Cancer Working Party. Neoadjuvant cisplatin, methotrexate, and vinblastine chemotherapy for muscle-invasive bladder cancer a randomised controlled trial. Lancet 1999 354 533-540. [Pg.301]

Angulo JC, Sanchez-Chapado M, Lopez JI, Flores N. Primary cisplatin, methotrexate and viblastine aiming at bladder preservation in invasive bladder cancer multivariate analysis on prognostic factors. JUrol 1996 155 1897-1902. [Pg.302]

Increased risk of myelosuppression with clozapine, azathioprine, cisplatin, methotrexate... [Pg.71]

CISPLATIN METHOTREXATE t methotrexate levels with t risk of pulmonary toxicity Cisplatin is the most common anticancer drug associated with renal proximal and distal tubular damage. Cisplatin could significantly l renal elimination of methotrexate It would be best to start with lower doses of methotrexate. It is necessary to assess renal function prior to and during concurrent treatment until stability is achieved. Monitor clinically and with pulmonaiy function tests... [Pg.330]

Tubular cell toxicity This involves the cellular transport systems mentioned previously and is thus dose dependent to a degree. Examples of tubular cell toxins include aminoglycosides, calcineurin inhibitors, amphotericin, antiviral agents, cisplatin, methotrexate, contrast agents and cocaine. [Pg.9]

The risk of methotrexate toxicity appears to be markedly increased by the previous use of cisplatin. Methotrexate may inhibit the ciearance of cisplatin. [Pg.647]

BCRP (ABCG2) Cisplatin, folate, methotrexate, mitoxantrone, topotecan, irinotecan, steroids (cholesterol, testosterone, progesterone), certain chlorophyll metabolites, and others... [Pg.7]

DOX, doxorubicine TAX, taxol MTX, methotrexate DDPt, cisplatin 5PU, flurouracil ETO, etoposide. [Pg.368]

Other drugs that are commonly implicated in causing ARF include acyclovir, adefovir, carboplatin, cidofovir, cisplatin, foscarnet, ganciclovir, indinavir, methotrexate, pentamidine, ritonavir, sulfinpyrazone, and tenofovir.45... [Pg.371]

Cushing s syndrome Cytotoxic drugs (e.g., methotrexate, cisplatin)... [Pg.854]

THC is effective in several chemotherapy regimens, including methotrexate and the doxorubicin/cyclophosphamide/fluorouracil combination. Cisplatin treatment, however, is more resistant. Side effects of THC are generally well tolerated, and use may be limited in the elderly or with higher doses. Nabilone is a synthetic cannabinoid that is more effective than prochlorperazine in chemotherapy-induced emesis, including cisplatin. Its side effects are similar to THC. Levonantradol is another synthetic cannabinoid with antiemetic effects, and may be administered orally or intramuscularly. The side effect of dysphoria may limit its use. [Pg.435]

Doxorubin Etoposide Methotrexate Mitoxantrone Cisplatin Vincristine Vinblastine Iiinotecan ... [Pg.45]

Decreased uptake Methotrexate, melphalan, nitrogen mustards, cisplatin... [Pg.8]

In phase II studies with topotecan alone, there is cytotoxic activity in lung cancer with intermittent dose schedules (33), as well as in lung cancer patients with topoisomerase II refractory disease (34). In advanced head and neck cancer topotecan is well-tolerated and has single-agent activity similar to that of cisplatin, 5-fluorouracil, and methotrexate... [Pg.98]

CAV = cyclophosphamide/doxorubicin/vincristine CEV = cyclophosphamide/epirubicin/vincristine CCM = cyclophosphamide/lomustine/methotrexate EA = etoposide/doxorubicin VMV/VAC = vincristine, methotrexate, VP-16/vincristine, doxorubicin, cyclophosphamide VAP = vincristine/doxorubicin/ procarbazine PE = cisplatin/etoposide. [Pg.199]

Morrell LE, Lee YJ, Hurley J, et al. A Phase II trial of neoadjuvant methotrexate, vinblastine, doxorubicin, and cisplatin in the treatment of patients with locally advanced breast carcinoma. Cancer 1998 82 503-511. [Pg.249]

Sternberg CN, Yagoda A, Scher HI, et al. Methotrexate, vinblastine, doxorubicin, and cisplatin for advanced transitional cell carcinoma of the urothelium efficacy and patterns of response and relapse. Cancer 1989 64 2448-2458. [Pg.300]

Loehrer PJ, Einhom LH, Elson PJ, et al. A randomized comparison of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma a cooperative group study. J Clin Oncol 1992 7 1066-1073. [Pg.300]

Loehrer PJ, Elson P, Dreicer R, et al. Escalated dosages of methotrexate, vinblastine, doxorubicin, and cisplatin plus recombinant human granulocyte colony-stimulating factor in advanced urothelial carcinoma an Eastern Cooperative Oncology Group trial. J Clin Oncol 1994 12 483-488. [Pg.300]

Roth BJ, Bajorin DF. Advanced bladder cancer the need to identify new agents in the post-M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) world. J Urol 1995 153 894-900. [Pg.300]

B = bleomycin, C = chlorambucil, CT = chemotherapy, DFS = disease-free survival, Ep = epirubicin, F = fluorouracil, I = ifosfamide, M = mitomycin C, Mtx = methotrexate, O = vincristine, OS = overall survival, P = cisplatin, RT = radiation therapy, V = vinblastine. [Pg.308]

See other pages where Methotrexate Cisplatin is mentioned: [Pg.43]    [Pg.70]    [Pg.73]    [Pg.149]    [Pg.293]    [Pg.718]    [Pg.50]    [Pg.293]    [Pg.587]    [Pg.286]    [Pg.309]    [Pg.998]    [Pg.149]    [Pg.43]    [Pg.70]    [Pg.73]    [Pg.149]    [Pg.293]    [Pg.718]    [Pg.50]    [Pg.293]    [Pg.587]    [Pg.286]    [Pg.309]    [Pg.998]    [Pg.149]    [Pg.144]    [Pg.593]    [Pg.367]    [Pg.289]    [Pg.290]    [Pg.556]    [Pg.348]    [Pg.222]    [Pg.214]    [Pg.372]    [Pg.301]    [Pg.222]   
See also in sourсe #XX -- [ Pg.647 ]



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Cisplatin

Cisplatin with methotrexate

Cisplatin/methotrexate/vinblastine

Cisplatin/methotrexate/vinblastine/doxorubicin

Cisplatine

Methotrexate

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