Chloride dietary intake

Treatment of asymptomatic hypervolemic hypotonic hyponatremia involves correction of the underlying cause and restriction of water intake to less than 1,000 to 1,200 mL/day. Dietary intake of sodium chloride should be restricted to 1,000 to 2,000 mg/day. 

Sodium, potassium, and chloride are electrolytes found in cow s milk for which the Food and Nutrition Board has estimated safe and adequate daily dietary intakes for infants, children and adolescents, and adults (NAS 1980A). Sodium functions in the body to maintain blood volume and cellular osmotic pressure and to transmit nerve impulses (NAS 1980A). The estimated safe and adequate daily dietary intake of sodium is 1100-3300 mg (2.8-8.4 g sodium chloride) for healthy adults (NAS 1980A). The American Medical Association, Council on Scientific Affairs (1979), suggested 4800 mg sodium per day as a tentative definition of moderation in sodium intake. 

Adequate dietary intakes of sodium and chloride for the adult are estimated to be 1.1-1.3 and t.7-5.1 g per day, respectively. These dietary salts are needed to replace obligatory losses in the urine and small losses in the sweat. Most of the sodium and chloride ions in the diet are absorbed by the jejunum and ileum only about 5% is lost in the fcccs. 

Potassium-rich foods often cannot completely replace potassium associated with chloride losses (vomiting, diuretics, or nasogastric suction) because it is almost entirely coupled to phosphate. Furthermore, increasing dietary intake of these foods may lead to unwanted weight gain. 

The cardiovascular system appears to be a target for MeHg toxicity in humans and animals. Blood-pressure elevations have been observed in occupationally exposed men (Hook et al. 1954) and in children treated with mercurous chloride for medical conditions. More recently, there is evidence that suggests effects at low levels of exposure. A recent study of 1,000 children from the Faroe Islands found a positive association between prenatal exposure to MeHg, and blood pressure and heart rate variability at age 7 (Sorensen et al. 1999). A Fiimish cotort study of 1,833 men linked dietary intake of fish and Hg concentrations in hair... 

The Food and Nutrition Board has removed the three electrolytes from its table of estimated safe and adequate daily dietary intake because sufficient information is not available to establish a recommended amount. The major dietary source of sodium and chloride is table salt (40% sodium and 60% chloride). Physicians still recommend that the intake of sodium be restricted to 1-2 g daily. The recommended intake of chloride is approximately 1.7-5.1 g daily. However, getting enough sodium and chloride is not a problem. In fact, sodium intake in the United States is about 5-7 g/day, far in excess of the 1-2 g/day required by a normal adult. 

There was a linear increase in fecal excretion of zinc in proportion to dietary intake in rats fed supplementations of 32 mg zinc/kg/day as zinc oxide for 7-42 days (Ansari et al. 1975) or 50-339 mg/kg/day for 21 days (Ansari et al. 1976). No differences in fecal excretion, total excretion, or retention of zinc were found among rats given diets containing different forms of zinc (Seal and Heaton 1983). Rats receiving 2.65 mg zinc/kg/day as zinc chloride, zinc sulfate, zinc phosphate, or zinc citrate, over a 4-day period excreted 87-98% of intake. 

Pangborn RM and Pecore SD. (1982) Taste perception of sodium chloride in relation to dietary intake of salt. Am J Clin Nutr, 35 510-520. 

In the United States, hypertension (high blood pressure) is the primary reason people visit doctor s offices, and more prescriptions are written for its treatment than any other health problem. In addition to the use of prescription drugs, hypertension is also usually treated by reducing or eliminating the dietary intake of sodium in the form of table salt (sodium chloride). Recently released research results indicate that combining an increase in dietary potassium intake with a reduction in sodium intake is probably the most important dietary decision (after excess weight loss) people can make to reduce cardiovascular diseases, including hypertension. 

Sodium and Hypertension. Salt-free or low salt diets often are prescribed for hypertensive patients (57). However, sodium chloride increases the blood pressure in some individuals but not in others. Conversely, restriction of dietary NaCl lowers the blood pressure of some hypertensives, but not of others. Genetic factors and other nutrients, eg, Ca " and K", may be involved. The optimal intakes of Na" and K" remain to be estabUshed... 

Dietary sodium restriction Reduce dietary sodium intake to no more than 100 mmol per day (2.4 g sodium or 6 g sodium chloride) 2-8 mm Hg... 

All patients with ascites require counseling on dietary sodium restriction. Salt intake should be limited to less than 800 mg sodium (2 g sodium chloride) per day. More stringent restriction may cause faster mobilization of ascitic fluid, but adherence to such strict limits is very difficult. Patients usually respond well to sodium restriction accompanied by diuretic therapy.14,22,31,32 The goal of therapy is to achieve urinary sodium excretion of at least 78 mEq (78 mmol) per day.22 While a 24-hour urine collection provides this information, a spot urine sodium/ potassium ratio greater than 1.0 provides the same information and is much less cumbersome to perform. 

Dietary calcium intake appears to affect lead absorption. An inverse relationship has been observed between dietary calcium intake and blood lead concentration in children, suggesting that children who are calcium deficient may absorb more lead than calcium replete children (Mahaffey et al. 1986 Ziegler et al. 1978). An effect of calcium on lead absorption is also evident in adults. In experimental studies of adults, absorption of a single dose of lead (100-300 ig lead chloride) was lower when the lead was... 

Studies In Dr. Greger s laboratory also have evaluated the Influence of tin or zinc retention In humans (61). Eight healthy male volunteers received their accustomed caloric Intakes, 3150 to 3700 kcal, as controlled, metabolic diets of real foodstuffs for two consecutive 20-day cycles two balance periods — comprising days 7-12 and days 13-18 of each cycle — were undertaken. The diets contained an average of 13.5 mg of zinc dally. In a randomized fashion, the rations during one of the dietary cycles had 50 mg of Sn as stannous chloride added. The dietary Sn/Zn... 

Hypertension is often treated with diuretics. Diuretics are drugs that promote the Joss of sodium from the body, though some diuretics can cause the loss of potassium, resulting in hypokalemia. The use of dietary supplements of K to correct this hypokalemia has been shown to be of benefit and to result in decreases in blood pressure. The best source of potassium is plant food, as is strikingly apparent from the data in Table IG.l however, the interest in nonfood supplements of potassium continues. One problem with potassium salts is that they taste bad and can produce nausea. Hence, there has been some interest in the manufacture of aesthetically acceptable forms of potassium salts. One form, a mixture of NaCl and KCl, is useful for those who feel compelled to add sodium chloride to their food. One study revealed that NaCI-KCl mixtures are accepted and their use can result in a reduction of sodium intake. The study, which involved normotensive subjects, did not lead to any consistent change in blood pressure (Mickeisen rt nI., 1977). 

Other methods used to decrease the recurrence of urolithiasis include dietary modifications that decrease calcium excretion and promote diuresis. Changing the diet from alfalfa to grass or oat hay decreases the calcium intake and should decrease the urinary excretion of calcium, since fecal calcium excretion is relatively constant in horses. Although this dietary change should decrease the total calcium excretion, it may also decrease the urinary excretion of nitrogen and the daily urine volume. The latter changes could enhance the supersaturation of urine. In theory, diuresis could be promoted further by the addition of loose salt (50-75 g per day) to the concentrate portion of the diet. However, in one study where ponies were fed sodium chloride (1, 3 or 5% of the total diet dry matter (1% is approximately 75 g sodium chloride for a 500 kg horse)), there were no differences in water intake, urine production or calcium excretion. 

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