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Cardiovascular complications

Only very recently have the government and other health agencies bowed to the preponderance of clinical, experimental, epidemiological, and historical evidence that moderate consumption of wine is not only not detrimental, but is beneficial. The proven benefit is in lowered incidence of cardiovascular complications in wine consumers. This apparently accounts for the relative health in this regard of people in Erance, Italy, and other Mediterranean countries even though their diet is otherwise less healthful (more fat particularly). [Pg.370]

Prosta.te Ca.ncer, Estrogen has an inhibitory effect on the prostate in addition to its suppression of gonadotropin secretion by the pituitary. The three- and five-year survival rates in prostate cancer patients with metastatic disease improved when treated with DES (7) alone or along with castration. However, DES does not improve the survival rates in patients whose carcinoma is confined to the prostate. Small doses of DES (1 mg/d) appear to retard prostate cancer growth and could reduce the cardiovascular complications associated with larger doses (5 mg/d) (135) (see... [Pg.244]

Hypokalemia. Hypokalemia associated with thia2ide diuretic therapy has been knpHcated in the increased incidence of cardiac arrhythmias and sudden death (82). Several large clinical trials have been conducted in which the effects of antihypertensive dmg therapy on the incidence of cardiovascular complications were studied. The antihypertensive regimen included diuretic therapy as the first dmg in a stepped care (SC) approach to lowering the blood pressure of hypertensive patients. [Pg.212]

Future efforts should be directed at optimizing current formulations to finally come up with an ideal oral contraceptive which would reduce the risk of breast, ovarian and endometrial cancer without any cardiovascular complications. [Pg.393]

It has been proposed that the development of the complications of diabetes mellitus may be linked to oxidative stress and therefore might be attenuated by antioxidants such as vitamin E. Furthermore, it is discussed that glucose-induced vascular dysfunction in diabetes can be reduced by vitamin E treatment due to the inactivation of PKC. Cardiovascular complications are among the leading causes of death in diabetics. In addition, a postulated protective effect of vitamin E (antioxidants) on fasting plasma glucose in type 2 diabetic patients is also mentioned but could not be confirmed in a recently published triple-blind, placebo-controlled clinical trial [3]. To our knowledge, up to now no clinical intervention trials have tested directly whether vitamin E can ameliorate the complication of diabetes. [Pg.1297]

Duckworth WC, McCarren M, Abraira C. Glucose control and cardiovascular complications the VA diabetes trial. Diabetes Care 2001 24(5) 942-5. [Pg.630]

Pulmonary hypertension develops late in the course of COPD, usually after the development of severe hypoxemia. It is the most common cardiovascular complication of COPD and can result in cor pulmonale, or right-sided heart failure. Hypoxemia plays the primary role in the development of pulmonary hypertension by causing vasoconstriction of the pulmonary arteries and by promoting vessel wall remodeling. Destruction of the pulmonary capillary bed by emphysema further contributes by increasing the pressure required to perfuse the pulmonary vascular bed. Cor pulmonale is associated with venous stasis and thrombosis that may result in pulmonary embolism. Another important systemic effect is the progressive loss of skeletal muscle mass, which contributes to exercise limitations and declining health status. [Pg.233]

Ergotamine derivatives Monitor cardiovascular complications as for serotonergic agents. [Pg.510]

Patients are at risk for the cardiovascular complications of hypertension, hyperlipidemia, and hyperglycemia. [Pg.694]

Discuss the cardiovascular complications of chronic South American trypanosomiasis. [Pg.1139]

Syphilis, caused by the spirochete Treponema pallidum, can have numerous and complex manifestations. Clinician familiarity, stage-specific diagnosis, and effective treatment are vital. Missed or inappropriately treated syphilis may result in cardiovascular complications, neurologic disease, or congenital syphilis. [Pg.1162]

The response varies, depending on the individual and the allergen. The worst case is that anaphylactic shock arises when gastrointestinal, cutaneous and respiratory symptoms occur in conjunction with a dramatic fall in blood pressure and cardiovascular complications. Death can occur within minutes of anaphylactic shock. Table 4 lists the other symptoms of IgE allergy. [Pg.51]

Common side effects include increased blood pressure, increased respiratory infections and increased platelet counts. Serious (rare) side effects were most often related to cardiovascular complications. Neorecormon is marketed by Roche. [Pg.276]

Cardiovascular disease Adverse reactions of iron dextran may exacerbate cardiovascular complications in patients with preexisting cardiovascular disease. [Pg.55]

Patients with type 1 diabetes (previousiy caiied juveniie or insulin-dependent diabetes) have an absolute deficiency of insulin, which produces chronic hyperglycemia (elevated blood glucose) with elevated risk for ketoacidosis and a variety of long-term complications, including retinopathy, neuropathy, nephropathy, and cardiovascular complications. [Pg.65]

Range of flu-like S5miptoms, e.g. fever, headache, chills Anorexia Strong fatigue Insomnia Cardiovascular complications Autoimmune reactions Hepatic decompression... [Pg.218]

Unless contraindicated, lipid lowering with HMGCoA reductase inhibitors (statins) should be used to treat hyperlipidemia for prevention of cardiovascular complications and are effective and well tolerated in those at least up to 80 years with coronary disease. [Pg.214]

Intramuscular injections can be given without siting an intravenous cannula, a difficult procedure in a struggling or uncooperative patient. It is necessary to use adequate restraint and exposure of the injection site so that relevant anatomical landmarks can be identified. Patients should be monitored after they have been sedated, as respiratory or cardiovascular complications can ensue, or the violent behaviour re-emerge. [Pg.506]

All hypotensive drugs lower systemic BP but, due to the specific characteristics of the glomerular capillary system, different agents may affect glomerular hemodynamics in different ways. This could be of major importance. During antihyper-tensive therapy, systemic BP may be reduced but glomerular pressure may be elevated. This may explain why the incidence of some cardiovascular complications such as stroke, has decreased, whereas the incidence of hypertensive nephropathy has remained high. [Pg.583]

Orally active agents used in the treatment of ED are more affected by aging and disease processes than are those injected intracavernosally. In addition, alterations in hepatic metabolism and/or renal clearance in the elderly man (see Chapter 6) influence the frequency of appearance of adverse reactions between several coadministered drugs in the treatment of ED. For example, the concomitant use of sildenafil and nitroglycerin is contraindicated by cardiovascular complications. Also, the use of testosterone in the presence of androgen-dependent tumors may promote tumor growth. [Pg.739]

Two different patterns of clonidine-induced cardiovascular complications have been described (Swanson et ah, 1995). One is characterized by decreased pulse and BP, often with associated EKG changes, fatigue, and sedation, and responds to a decrease in dosage. The other presents with tachycardia, tachypnea, with or without fever, anxiety, panic, and acute mental status changes, and is often associated with a missed dose or an abrupt taper. This pattern often responds to reinstituting the dosage and slowly tapering as necessary. [Pg.269]

Zielinski RJ, Roose SP, Devanand DP, et al Cardiovascular complications of ECT in depressed patients with cardiac disease. Am J Psychiatry 150 904-909, 1993 Zimmerberg B, Farley MJ Sex differences in anxiety behavior in rats role of gonadal hormones. Physiol Behav 54 1119-1124, 1993 Zimmerberg B, Brunelli SA, Hofer MA Reduction of rat pup ultrasonic vocalizations by the neuroactive steroid allopregnanolone. Pharmacol Biochem Behav 47 735-738, 1994... [Pg.773]

Tight control of diabetes, with reduction of HbAic from 9.1% to 7%, was shown to reduce the risk of microvascular complications overall compared with that achieved with conventional therapy (mostly diet alone, which decreased HbAic to 7.9%). Cardiovascular complications were not noted for any particular therapy metformin treatment alone reduced the risk of macrovascular disease (myocardial infarction, stroke). Epidemiologic analysis of the study suggested that every 1% decrease in the Aic achieved an estimated risk reduction of 37% for microvascular complications, 21% for any diabetes-related endpoint and death related to diabetes, and 14% for myocardial infarction. [Pg.937]

The claimed body-building effect of the so-called anabolic compounds reflects their ability to promote muscular development, even beyond physiological limits, and this can bring with it cardiovascular complications. Surreptitious misuse by athletes remains a recurrent problem in professional sport (73) apart from the cardiovascular risks, one observes numerous physiological changes, including effects on plasma levels of enzymes, minerals and vitamins and reduced concentrations of HDL cholesterol (74). [Pg.142]

The risk of thromboembolic complications when diethylstilbestrol is used in treating prostatic cancer is well documented, but there has been some doubt as to the mechanisms involved. Oral diethylstilbestrol diphosphate 300 mg/day has been compared with LR-RH agonist therapy or no treatment in 35 patients with prostatic cancer (5). Diethylstilbestrol reduced the concentrations of protein S to below the lower limit of normal in 24 of the 35 cases. There was also some reduction in antithrombin III concentrations. These results were consistently confirmed in a follow-up group of eight further patients who took diethylstilbestrol. Since these very low concentrations of protein S are virtually the same as those found in congenital deficiency, it seems likely that this plays a role in the development of cardiovascular complications during diethylstilbestrol treatment. [Pg.167]


See other pages where Cardiovascular complications is mentioned: [Pg.112]    [Pg.124]    [Pg.124]    [Pg.305]    [Pg.391]    [Pg.755]    [Pg.550]    [Pg.175]    [Pg.1474]    [Pg.235]    [Pg.310]    [Pg.37]    [Pg.1251]    [Pg.118]    [Pg.213]    [Pg.220]    [Pg.682]    [Pg.709]    [Pg.712]    [Pg.381]    [Pg.82]    [Pg.419]    [Pg.221]    [Pg.191]   
See also in sourсe #XX -- [ Pg.629 ]




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Complicance

Complicating

Complications

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