Arterial graft

Finally, aspirin has also been used to prevent thrombus formation in peripheral veins (deep vein thrombosis [DVT]), and aspirin is sometimes used as an adjunct or alternative to anticoagulants (heparin, warfarin) that are routinely used to treat DVTs.8 Aspirin can likewise be administered to prevent thromboembolism following surgical procedures such as coronary artery bypass, arterial grafts, endarterectomy, and valve replacement 45,78 By preventing platelet-induced thrombogenesis, aspirin helps maintain patency and prevent reocclusion of vessels following these procedures. 

Moon MR, Sundt TM, 3rd, Pasque MK, et al. Influence of internal mammary artery grafting and completeness of revascularization on long-term outcome in octogenarians. Ann Thorac Surg 2001 72(6) 2003-2007. 

GoMmanM, HallC, DykesJ, Hawker RJ, McCollum CN Does II 1-indium platelet deposition predict patency in prosthetic arterial grafts Brit. J. Surg. 635,1983... 

A patient with underlying chronic renal insufficiency, who underwent coronary bypass artery grafting and was treated with intravenous aminocaproic acid, developed hyperkalemia (6.7 mmol/1) (65). There was no other obvious cause for the acute increase in serum potassium. 

A 29-year-old woman took bromocriptine 5 mg/day postpartum to suppress lactation (1). Four days later she developed an acute anterior myocardial infarction. Angiography showed dissection of the left main and anterior descending arteries, with occlusion of the latter. She recovered after emergency arterial grafting. 

J. N. Fabiani, O. Ponzio, 1. Emerit, S. Massonet-Castel, M. Paris, P. Chevalier, V. Jebara, A. Carpen-ticr, Cardioprotective effect of triraetazidine during coronary artery graft surgery, J Cardiovasc Surg 3, 486-491 (1992). 

Feng et al. [139] studied the activity of TM reconstituted into the PEM/HBM assembly described in Sect. 2.1. TM is a type ITMP that is a receptor for thrombin and mediates protein C activity in anticoagulant and antiinflammatory pathways. TM functionalization represents a promising strategy to control thrombus formation on the surface of a biomaterial that comes into direct contact with blood, such as the inner surface of an arterial graft. TM was incorporated into vesicles of mono-acrylatePC (Fig. 1) that were then fused onto an amphiphilic terpolymer/PEM/glass coverslip (see Fig. 2). The eosin Y/triethanolamine method [56] was used to polymerize the lipids, after which the supported assembly could be removed from solution for characterization purposes. 

Everted coronary artery graft with stenosis [48] Platelet rich (rt-PA resistant) Coronary blood flow Adjunctive agents in thrombolysis of rt-PA resistant platelet rich thrombus... 

Clinical uses include treatment of acute myocardial infarction, pulmonary embolism and peripheral thromboembolism and in the restoration of circulation through arterial grafts and intravenous catheters. 

USE Esterifying agent in the production of cellulose propionate (thermoplastic) and other propionates, e.g.. calcium propionate, used as mold inhibitors and preservatives in the manuf of ester solvents, fruit flavors, and perfume beees. fl-Proptolactone is useful in organic syntheses and to preserve arterial grafts. 

Thrombotic complications are frequently encountered when blood is exposed to the surfaces of hemodialysis devices, heart-lung machines, arterial grafts, artificial heart components and other prosthetic devices. The blood platelets are particularly vulnerable to these adverse effects which may include a decrease in platelet count, shortened platelet survival and attendant higher platelet turnover, and altered platelet function. However the interaction of platelets with an artificial surface exposed to blood must be preceded by the interaction of the molecular components of plasma, particularly the plasma proteins, with the surface (1,2). This is due to the prepon-... 

Clowes, A. W., Kirkman, T. R. and Reidy M. A., Mechanisms of arterial graft healing rapid transmural capillary ingrowth provides a soiuve of intimal endothelium and smooth muscle in porous PTFE prostheses, Am. J. Pathol., 123(2), 220, 1986. 

Studies of the fatigue behavior of vapor-deposited pyrolitic carbon fibers (4000 to 5000 A thick) onto a stainless steel substrate showed that the film does not break unless the substrate undergoes plastic deformation at 1.3 x 10 strain and up to one million cycles of loading. Therefore, the fatigue is closely related to the substrate, as shown in Figure 39.17. Similar substrate-carbon adherence is the basis for the pyrolitic carbon deposited polymer arterial grafts [Park and Lakes, 1992). 

Commercial Products Collagen coated and gelatin coated vascular grafts [Jonas etal., 1988, Li, 1988] chemically processed human vein graft [Dardiketal., 1974] bovine arterial grafts [Sawyer et al., 1977] porcine heart valves [Angell et aL,... 

Stefanadis, C., Toutouzas, K., Tsiamis, E., Kallikazaros, L, Stralos, C., Vlachopoulos, C., Vavuranakis, M., and Toutouzas, P., Implantation of stents covered by autologous arterial grafts in human coronary arteries A new technique, y. Invasive Cardiol., 2CKK)a 12(1) 7-12. 

Edwards WS, Tapp JS. Chemically hreated nylon tubes as arterial grafts. Surgery 1955 38 61-70. 

Gross RE, Hurwitt ES, Bill Jr AH, et al. Preliminary observations on the use of the human arterial grafts in the treatment of certain cardiovascular defects. N Engl J Med 1948 239 578-91. 

Dubost C, Allary M, Oeconomos N. Resection of an aneurysm of the abdominal aorta reestablishment of the continuity by a preserved human arterial graft, with result after five months. Arch Surg 1952 64 405-8. 

Sparks CH. Silicone mandril method for growing reinforced autogenous femoropopliteal artery grafts in situ. Ann Surg 1973 177 293-300. 

Rosenberg N. The bovine arterial graft and its several applications. Surg Gynecol Obstet 1976 142 104-7. 

Dardik I, Dardik H. The fate of human umbiheal cord vessels used as interposition arterial grafts in the baboon. Surg Gynecol Obstet 1975 140 567-71. 

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