Arterial grafts compliance

Kidson IG and Abbot WM, Low compliance and arterial graft occlusion Circulation, September 1978 58 3, Pt 2,11-14. 

MiyawakiF,HowTV and Annis D, Effect of compliance mismatch on flow disturbances in a model of an arterial graft replacement, Med. Biol. Eng. Comput., 1990 28 457-464. 

Sonoda H, Takamizawa K, Nakayama Y, Yasui H, Matsuda T. Coaxial double-tubular comphant arterial graft prosthesis time-dependent morphogenesis and compliance changes after implantation. J Biomed Mater Res A 2003 65A 170-81. 

The two major problems in materials behaviour in work of this type lie in the achievement of patency at the junction with natural tissue and the avoidance of unacceptable levels of thrombogenicity. In relation to the former problem, the extent to which the elastic properties of host tissue and graft are matched has previously been suggested as an important factor (i.e., this Series, Volume 1, p. 421, refs. 81 and 82). Further clinical results accumulated over a two-year period support this proposition, indicating patency success rates of over 80% in artery grafts with matched compliance and less than 45% with mismatched grafts. ... 

Another alternative for decreasing rejection and infection rates is the creation of a biodegradable device. A biodegradable cross-linked, elastic salmon collagen scaffold with wall compliance similar to native artery has been used as a vascular graft. 

Artery or graft specimen Wall thickness (mm) Diameter (mm) Compliance, Cv(kPa- ) Elastic mocdulus, p (kPa) Stiffness parameter, j8... 

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