Stress and Anxiety

Titus GAL3 antagonists may represent an alternate class of therapeutic agents for the treatment of depression, anxiety, and stress-related disorders. 

Neuropeptide Y (NPY) and its receptors may also be important in the regulation of anxiety and stress. NPY is synthesized in the arcuate nucleus, which receives LC input. In a number of rodent models, NPY administration has anxiolytic and, at somewhat higher doses, sedative effects. Likewise, NPY antagonizes CRH-induced stress responses, and suppresses LC firing when injected... 

Chlormezanone improves the emotional state of the patient, relieving moderate anxiety and stress. However, it has a number of side effects, and because it does not have any advantage over other anxiolytics, it is rarely used in practice. Synonyms of this drag are trancopal, alinam, flexipirin, and others. 

Although substance P (SP) and its receptor, neurokinin 1 receptor (NKIR), have been implicated in the control of mood, anxiety, and stress, the efficacy of NK1R antagonists as both antidepressants and anxiolytics has been matter of considerable debate (Lesch 2001a). Santarelh and associates (2001) have recently made a strong argument for a critical role of the SP/NKIR system the modu-... 

Merikangas KR (2002) Genetic and other vulnerability factors for anxiety and stress disorders. In Davis KL, Charney D, Coyle JT, Nemeroff C (eds) Neuropsychopharmacology— the fifth generation of progress. Lippincott Williams and Wilkins, Philadelphia, pp 867-882... 

Contemporary anesthetic management requires (1) rapid loss of consciousness, which eliminates awareness, memory of pain, anxiety, and stress throughout the surgical period (2) a level of analgesia sufficient to abohsh the reflex reactions to pain, such as muscular movement and cardiovascular stimulation (3) minimal and reversible influence on vital physiological functions, such as those performed by the cardiovascular and respiratory systems (4) relaxation of skeletal muscle to facilitate endotracheal intubation, provide the surgeon ready access to the operative field, and reduce the dose of anesthetic required to produce immobihty (5) lack of... 

They have selective action on limbic system and have little effect on other body systems. They help in improving the anxiety and stress related symptoms. They are widely used because of lower dependence producing liability and wide margin of safety. 

If tranquillisers are no longer seen as a long-term solution to anxiety and stress-related problems, then what is Much of the experience gained in managing withdrawal points to fruitful areas of investigation in the search for alternatives. Alternative medication... 

Main actives Valepotriates (0.5-2.0%), volatile oil (0.2-1.0%) and valeric acid (0.1-0.9%). Benefits Valerian has been used as a daytime sedative to reduce anxiety and stress and it has been demonstrated to reduce the time it takes to fall asleep. Valerian root extracts and volatile oils are used as components in the flavour industry, especially in alcoholic beverages such as beers and liqueurs and in soft drinks such as root beers. They have also been used in tobacco flavours. 

Swanson C. J., Bures M., Johnson M. P., Linden A. M., Monn J. A., and Schoepp D. D. (2005). Metabotropic glutamate receptors as novel targets for anxiety and stress disorders. Nat. Rev. Drug Discov. 4 131-144. 

Kava is sometimes used during religious ceremonies and is currently promoted for relief of anxiety and stress. 

Blood pressure similarly rises with anxiety and stress during everyday life. That s a natural and usually harmless phenomenon. You re driving along the road, let s say, and a child runs out into the... 

George called your office yesterday requesting an appointment to discuss recent feelings of "anxiety and stress."... 

Learning nondrug-usc skills for dealing with anxiety and stress... 

In the 1990s, kava emerged as a popular item within the homeopathic and, more generally, the hohstic health and herbal marketplace. Today, kavalactones, sometimes combined with other substances in tonics or capsules, are on sale as dietary supplements in health food stores, pharmacies, and supermarkets around the world. By 1998, kava sales in the US reportedly had grown to about 20 million. Kava is packaged and marketed principally as a treatment for anxiety and stress, although other benefits of the plant are also touted. Aloha Seed Herb, for example, markets Kava-for-Health on the Internet ... 

Balsam fir To relieve muscle aches and pains for relieving anxiety and stress-related conditions to fight colds, flu, infections for relieving bronchitis and coughs said to ground one mentally... 

Bergamot Balancing nervous system relieving anxiety and stress lifting melancholy for restful sleep as an antiviral treatment of cold sores, psoriasis, eczema insect repellent... 

Carrot seed For toning and rejuvenating mature skin, wrinkles, scars for eczema and psoriasis as a stimulant to immune and lymphatic systems for relieving premenstrual syndrome and regulating monthly cycles to ease anxiety and stress... 

The question arises whether anxiolytic activity must always be accompanied by concomitant skeletal muscle relaxant and anticonvulsant activity as well as strong sedation. Can an anxioselective drug exist that will not interact significantly and additively with CNS depressant compounds, particularly alcohol More significantly, both from a medical and sociologic viewpoint, will it be possible to treat anxiety and stress without the added complication of potent sedative effects, dependency, and abuse ... 

Never skip breakfast You need the protein and complex carbs to ground you, or you risk flying into the air, unmoored by moodiness, anxiety, and stress, with any random worry able to blow you off course. 

---