Aloins

Weiner, Kolltnan, I ,.A, Nguyen, D. f. Case, n,A,. All all aloin force field for simulations of proteins and nucleic acids,/. Cornpui. Chem. 7 230 252, 1986. 

The MM+ force field uses special values for ihe bending force coii-sianis when Lhe aloins are in a Ihree- or fmir-niembered ring. 

A and B (a sini pic I uncLion of thc aLoinic orbital Lypc i. In ihocase of an sp prod 11 cl, ihm is a vcclor of lenglli D, aloin ic units poin ting along p axis,... 

S)-10-p-D-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)anthracen-9(10H)-one trivial names aloin A, (10S)-barbaloin... 

Males et al. [103] used aqueous mobile phase with formic acid for the separation of flavonoids and phenolic acids in the extract of Sambuci flos. In a cited paper, authors listed ten mobile phases with addition of acids used by other investigators for chromatography of polyphenolic material. For micropreparative separation and isolation of antraquinone derivatives (aloine and aloeemodine) from the hardened sap of aloe (Liliaceae family), Wawrzynowicz et al. used 0.5-mm silica precoated plates and isopropanol-methanol-acetic acid as the mobile phase [104]. The addition of small amounts of acid to the mobile phase suppressed the dissociation of acidic groups (phenolic, carboxylic) and thus prevented band diffusions. 

FIGURE 11.19 PLC of Aloe on precoated silica plate with preconcentrating zone developed with AcOEt + MeOH + water (77 13 10). A1 — aloine, Ae — aloeemodine. (For details, see Wawrzynowicz, T., Waksmundzka-Hajnos, M., and Mulak-Banaszek, K., J. Planar Chro-matogr., 1, 315-318, 1994.)... 

It has been found that numerous plants contain I-C-substituted an-hydroalditols. For example, barbaloin, a major constituent of commercial aloin, is 10-(a-D-glucopyranosyl)-l,8-dihydroxy-3-(hydroxy-methyl)anthrone.45 Numerous other 1-C-substituted anhydroalditols have been isolated from a variety of plant sources by various investigators. 

Aloe barbadensis Miller var. chinensis Berger A. vera L. Lu Wen (Aloe) (aerial part) Aloins, barbaloin, aloe-emodin, polysaccharides 49,50,403,450,510 Laxative, stomachic, emmenagogue. 

N.A. Aloin isobarbaloin, aloeresin A, B, aloesin glycone, aloesone, emodin, chrysophanic acid, 1,8-dihydroxy-anthracene derivatives, barbaloin, anthaquinone glycosides.99-100 108 109 510-511 Purgative, eupeptic, and cholagogue effect. It is a laxative and cathartic. Juice from leaves used for cuts and other skin problems. 

The curve separating displaced and undisplaced positions of a crystal, and thus at the center of a dislocation, is lermed the dislocation line. Within a distance of one or two lattice constants of Ihe dislocalion line the aloins are displaced by an amount more than can be represented fairly as a strain A screw location may have a substantial hole down the dislocation line, through which impurity atoms may diffuse. 

Aloe s most important ingredients — aloin, barbaloin, and aloe-emodin — are responsible for its cathartic action (see Chapter 12). 

Scientific research has proved in recent years that the rind and the outer leaf, normally thrown away, contain much more active therapeutic ingredients. On the other hand, the gel is sensitive to heat and light, and can quickly deteriorate at high temperature. For these reasons, the gel is now available as a cold-processed extract obtained from aloe whole leaf. The fresh whole leaf is cut into small pieces and whipped to yield a homogeneous yellowish or reddish material. The product (10% aloe leaf and 90% water), concentrated, and in some cases deprived partially of aloins, is bitter. 

Aloe latex is an active laxative. Its effect is due to anthraquinone glycosides, aloin A and B (formerly designated barbaloin). Glycosides are probably chemically stable in the stomach (under... 

As described in previous sections, the inspissated juice of the leaves of various species of Aloe from the West Indies, Africa, etc., furnishes the commercial varieties of aloes, which differ somewhat in composition and action. They contain anthraquinone derivatives, especially aloins... 

Aloin, R.C., Curtain, C.C., Gordon, L.M. (Eds.), Drug and Anesthetic Effects on Membrane Structure and Function, Wiley-Liss, New York 1991. 

Retinyl esters Retinyl esters Retinyl esters Carotenoid isomers N-nitrosodiethanolamine in cosmetics Aloins, and related constituents of aloe Food colorants and aromatic glucoronides Azo and antraquinone textile dyes Alkaloids... 

Aloin (= Barbaloin) (anthrone glycoside) Abeferox, A. perryi, A. vera (Liliaceae) [leaf], Frangula alnus, Frangula purshiana (Rhamnaceae) PS - eEF-2 [purgative]... 

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