Aloe ferox

Aloe vera leaf (Aloe ferox, A. barbadensis) has the following uses ... 

ALOE VERA LEAF (ALOE FEROX, A. BARBADENSIS)... 

A 47-year-old South African man developed acute oliguric renal insufficiency and liver dysfunction after taking an herbal medicine prescribed by a traditional healer to clean his stomach (8). After withdrawal of the remedy and dialysis he recovered slowly, but his creatinine concentration did not fully normalize. Analysis of the remedy showed that it consisted of A. capensis Aloe ferox Miller), which contains the nephrotoxic compounds aloesin and aloesin A. 

This is a common species of aloe and is derived from Aloe ferox. It is reported to be the most extensively used plant substance as an herbal remedy in South Africa [9]. The aloe is also identified as one of the most commonly used herbal propriety products [22]. It is not considered toxic. Therefore the case [21] discussed above, must have had other additives that... 

ALOES Many different types of Aloes have been used in medicine as laxatives bnt the two main types now recognised are Cape Aloes from Southern Africa and Barbados Aloes from the Caribbean. Cape Aloes consists of the concentrated and dried jnice of the leaves of various species of Aloe, mainly Aloe ferox Miller and its hybrids. Barbados Aloes is produced from Aloe barbadensis Miller (also known as Aloe vera L.), family Liliaceae. (Fig. 6) The different Aloe plants are all succulent cactns-like plants with large fleshy water-storing leaves. These are cnt near the base and the jnice from the pericyclic cells is collected. This jnice is then concentrated by heat and allowed to dry into dark masses. 

Cape aloe A much-branched South African plant (Aloe ferox) with reddish, prickly, succulent leaves. 

Miller,. 4Joe vera Linne) Or Cape Aloe (,Aloe ferox Miller and hybrids), family Litiaeeae. Habit. Curasao in Dutch West Indies Cape, in Southern Africa. Constii. Curasao IS-25% a loin (curagaloin), Cape 4.5-9% aloin (cap-alojn) all the aloes, moreover, contain resin, emodin and volatile oil. Aloe yields not less than 50% of water-sol extractive. Structure Of aloerestn A, a major constituent of Cape Aloe P. Gramatica et al, Tetrahedron Letters 23, 2423 (1932). Review Chem. Week. 78(1). 44 (Jan. 7. 1956). 

Alcea rosea root Aloe ferox leaf gel Aloe perryi leaf gel Aloe vera leaf gel... 

Constit. of the dried exudate of Aloe ferox. Amorph. solid. Mp 140-143°. 

Constit. of Aloe ferox. Pale yellow cryst. (MeOH). Mp 124-129°. 

Aloe vera yields Curagao aloe or Barbados aloe, which is produced in the West Indies (Curasao, Aruba, Bonaire). Aloe ferox and its hybrids yield Cape aloe that is produced in South Africa. Other A/oc species yield aloes of lesser importance. 

One of the main groups of phenolic constitnents are anthraquinones, and these have been reported in roots of aloe (16, 24, 25), in leaf exudates of A. elgonica (26) and A. ferox (27). However, in one study, anthraquinone glycosides were not been detected in the root (16). 

Although A. vera sa.dA.ferox species are the most important commercial in the international markets, it is largely the presence of anthrones and polysaccharides content that determine the plants effectiveness for therapeutic activity. There are other Aloe species that could be promoted for similar purposes when those species contain one or both groups of bioactive compounds. The biological activities of the Aloe sp could be attributed to synergic actions of the components rather than from a single component 16). 

Streptococcus pyogenes (90). The activity of three compounds (aloe-emodin, chiysophanol and aloin A) isolated from A. ferox have been shown to be effective against both Gram negative and Gram positive bacteria, demonstrating a broad spectram potential of the plant as antimicrobial agent (97). 

The genus Aloe from Africa is highly diverse with hundreds of species, however, only a minor number of these diversity has been explored in search for new bioactive components. Mat r of them are being use extensively by traditional healers, suggesting that the genus can be the source of potential new compounds that are waiting to be discovered or commercialized. A. vera and. ferox are two popular and well species that contain many unique constituents with biological activity and with application to the pharmaceutical, cosmetic, personal care products sectors as well as to the continued uses in traditional medicines. 

Aloe barbadensis Miller, Curacao aloe, A. vera Linne, aloe vera, A. vera Toumefort ex Linne, Barbados aloe, A. vulgaris Lamark, Cape aloe, Zanzibar aloe, Socotrine aloe, A.ferox Miller (Anonymous, 1992), A. perryi Baker, A. africana Miller, A. capensis, A. spicata Miller, natal aloes, mocha aloes (Wichtl,... 

C15H10O5. Mr 270.24, orange needles, mp. 223 - 225 °C, uv 430 nm (C2H5OH), soluble in ether, benzene, and hot ethanol. A. is named after the aloe, the concentrated leaf juices of various Aloe species (A. ferox, A. barbadensis, Liliaceae) and occurs additionally in free form and as the corresponding anthrone glycosides in Rhamnus, Rheum, Rumex, and Cassia species. In addition to laxative action it also exhibits an antileukemic effect and is used as starting material for the synthesis of anthracycline antibiotics. 

Aloe-emodin aadAloin in Aloe-brown from plant species such as Aloe barbadensis Miller (also known as A. vera Linne), A. ferox and A. perryi. 

Aloe spp. A. barbadensis Miller A. epatia Liliaceae A. ferox A. perryi... 

Source Aloe vera (L.) Burm. f. (syn. Aloe barbadensis Mill.) A. perfoliata L. var. vera L.) A. arborescens Miller var. natalensis Berger A. ferox Mill, and its hybrids with A. africana Mill, and A. spicata Baker A. perryi Baker (Family Liliaceae). 

Regulatory Status. Aloe has been approved for food use as a natural flavoring ( 172.510) and is regulated in the United States as a dietary supplement. Dried Aloe vera leaf juice (and preparations) calculated to contain at least 28% hydroxy anthracene derivatives (as anhydrous barbaloin), and A. ferox dried leaf juice (and preparations) calculated to contain at least 18% hydroxy anthracene derivatives (as anhydrous barbaloin), are the subject of a German BGA monograph (blumenthal 1). 

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