Cape aloes

Luyckx VA, Ballantine R, Claeys M, Cuycketrs F, Van den Heuvel H, Cimanga RK, Vhetinck AJ, De Broe ME, Katz U. Herbal remedy-associated acute renal failure secondary to Cape aloes. Am J Kidney Dis 2002 39(3) E13. 

To support its safety. Van Wyk [23] mentions the medicinal uses of the Cape aloe. The yellow juice from the leaves is dried and a small crystal (the size twice that of a match head) of the dried substance is taken orally as a laxative. Its use as a laxative has also been important from a commercial point of view. The export market has been a valuable source of revenue for SA. It may also be used for arthritis, but at a much smaller dose than that required for a catharsis. Van Wyk mentions that eczema, hypertension and stress have also been included in the hst of indications for this product. One is uncertain as to how these indications were arrived at and whether there is any substantive evidence of efficacy, with the use of aloes, in the treatment of these conditions. 

Alexandrian Senna Pods Aniseed Arnica Flower Bearberry Leaf Cape Aloes Can/i fructus Centaurii herba Crataegi folium cum flore Dandelion Root Echinaceae pallidae radix Eucalypti aetheroieum Fennel... 

ALOES Many different types of Aloes have been used in medicine as laxatives bnt the two main types now recognised are Cape Aloes from Southern Africa and Barbados Aloes from the Caribbean. Cape Aloes consists of the concentrated and dried jnice of the leaves of various species of Aloe, mainly Aloe ferox Miller and its hybrids. Barbados Aloes is produced from Aloe barbadensis Miller (also known as Aloe vera L.), family Liliaceae. (Fig. 6) The different Aloe plants are all succulent cactns-like plants with large fleshy water-storing leaves. These are cnt near the base and the jnice from the pericyclic cells is collected. This jnice is then concentrated by heat and allowed to dry into dark masses. 

Medicinal Aloes contains C-glycosides similar to those of Cascara as well as primary glycosides called Aloinosides and also various resins. The main constituent is Barbaloin. Pharmacopoeial-quality Cape Aloes must... 

Aloe barbadensis Miller, Curacao aloe, A. vera Linne, aloe vera, A. vera Toumefort ex Linne, Barbados aloe, A. vulgaris Lamark, Cape aloe, Zanzibar aloe, Socotrine aloe, A.ferox Miller (Anonymous, 1992), A. perryi Baker, A. africana Miller, A. capensis, A. spicata Miller, natal aloes, mocha aloes (Wichtl,... 

Cape aloe A much-branched South African plant (Aloe ferox) with reddish, prickly, succulent leaves. 

A Cape Aloe (I) is characterized by the yellow Huorescent zone of aloin (R, — 0.5/T2) and aloe-emodin (solvent front). The zones of aloere.siits such as aloesin A and B (R, 0.55 and R 0.25, respectively) fluoresce light blue. 

Trade samples of Cape aloe (2) can show besides the yellow fluorescent aloin and aloe-emodin, additional yellow zones of the aloinosides A/B (R, 0.25-0.3) and additional glycoside.s (e.g. R, - 0.7.5). The blue fluorescent zones are less prominent than in sample 1 (e.g. aloe resiu.s). 

Note 7-hydroxyalDiii (T2) a characteristic compound in Curacao aloe.s (3) is absent in Cape aloes (1,2). 

Cape aloe I- + H- -h Cape and Curacao aloes arc dilTercntiatcd... 

Miller,. 4Joe vera Linne) Or Cape Aloe (,Aloe ferox Miller and hybrids), family Litiaeeae. Habit. Curasao in Dutch West Indies Cape, in Southern Africa. Constii. Curasao IS-25% a loin (curagaloin), Cape 4.5-9% aloin (cap-alojn) all the aloes, moreover, contain resin, emodin and volatile oil. Aloe yields not less than 50% of water-sol extractive. Structure Of aloerestn A, a major constituent of Cape Aloe P. Gramatica et al, Tetrahedron Letters 23, 2423 (1932). Review Chem. Week. 78(1). 44 (Jan. 7. 1956). 

Aqueous extracts of cape aloe (5 to 100 mg/ml) gave mixed results for mutagenicity, with mutagenicity reported for tests in the Bacillus subtilis rec-assay but no mutagenicity shown in Salmonella strains TA98 or TAIOO (Morimoto et al. 1982). 

Cape Aloe jB = Cortex Frangulae (7 = Cortex Rhamni Purshianae D = Rhizoma Rhei E = Folia Sennae. The spot colours quoted were obtained with the untreated chromatogram by inspection in UV light... 

Aloe vera yields Curagao aloe or Barbados aloe, which is produced in the West Indies (Curasao, Aruba, Bonaire). Aloe ferox and its hybrids yield Cape aloe that is produced in South Africa. Other A/oc species yield aloes of lesser importance. 

Overdosage of drug aloe fluid and electrolyte imbalance, abdominal pain, bloody diarrhea, hemorrhagic gastritis, and sometimes nephritis (blumenthal 1 gosselin martindale), the latter also associated in case studies with prolonged use of Cape aloes containing aloe-sin and aloeresin A. ... 

Crude, aloin, and extracts in various forms. Crude Barbados and Cape aloes are official in U.S.P. 

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