Allergic asthma/rhinitis

Atopy A genetic predisposition to develop type I hypersensitivity reactions against common environmental antigens commonly seen in patients with allergic rhinitis, asthma, and atopic dermatitis. 

Flunisolide is a fast-acting corticoid designed for the treatment of allergic rhinitis, asthma, and other allied respiratory disorders in humans. As the quantum of drug delivered by inhalation (/. e., the usual route of administration of the drug), is invariably small, the plasma-levels attained can also be fairly small. Hence, there is a dire need for a sensitive method of plasma concentration evaluation which is satisfied by radioimmunoassay. 

The most severe side effects, which may occur during SLIT, consist of the allergic symptoms themselves such as allergic rhinitis, asthma attacks or atopic eczema [31]. Anaphylactic reactions are not expected, because allergens do not penetrate the mucosa in an unlimited way, thus entering blood vessels, as is possible after injections. 

There is steady growing evidence that environmental exposure to insects at home and in the workplace are the frequent causes of allergic sensitization (Arlian 2002). Subsequently clinical symptoms are mainly of respiratory nature, manifested in allergic rhinitis, asthma, and urticaria (Steen et al. 2004), and in some documented cases also via ingestion, causing systemic anaphylaxis. 

Indications Allergic rhinitis, Asthma Category Corticosteroid, inhaled Half-life N/A... 

Indications Allergic rhinitis, asthma Category Corticosteroid Half-life 5-7 hours... 

Synonyms cromolyn sodium disodium cromoglycate Trade names Colimune Crolom Cromlom Cromoptic Fivent Gastrocrom (Celltech) Intal (Monarch) Nalcrom Nasalcrom (Pfizer) Opticrom (Allergan) Rynacrom Indications Allergic rhinitis, asthma, mastocytosis Category Mast cell stabilizer Half-life 80 minutes... 

Examples Allergic rhinitis, asthma, systemic anaphylaxis Some drug allergies (eg.. penicillin) Serum sickness, Arthus reaction Tuberculin reaction, contact dermatitis (with IVc) Chronic asthma, chronic allergic rhinitis Maculopapular exanthema with eosinophilia Contact dermatitis, Maculopapular and bullous exanthema, hepatitis AQEP Beh t disease... 

As in other types of drug hypersensitivity, skin testing often yields variable results. Farah and Shbaklu (1971) reported positive skin tests on intradermal injections of progesterone and confirmed the sensitivity of both their patients by passive cutaneous transfer tests. Falliers (1974) noted that 10 out of 11 women with either allergic rhinitis/asthma or urticaria had strong positive wheal and erythema reactions. In contrast, the patients treated by Pelikan (1978) did not show a good correlation between the results of nasal provocation and either scratch or patch tests. 

Allergic rhinitis, asthma and/or atopic dermatitis were seen in 58 of 234 bakery employees (25%) 14 had atopic dermatitis. Of these 14, 3 had positive intracu-taneous tests to one or more of the flours they used. One of those who had a positive skin test experienced aggravation of hand eczema upon contact with flour, and another experienced aggravation of atopic dermatitis of the neck (Jarvinen et al. 1979). 

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