Alcohol mixed with other drugs

Physical effects of high doses of ketamine include decreased respiration and heart rate, increased blood pressure, and the possibility of vomiting and convulsions. These can lead to cardiac and respiratory arrest, coma, and death. The risk of ketamine overdose is much greater when it is mixed with other drugs such as alcohol, Ecstasy, caffeine, or cocaine. Overdoses of ketamine have been reported when people boost the drug (take another dose before the first dose wears off) to prolong its psychedelic effects. 

However, if more than 3-5 mg kg-1 is needed over 24 h, it should be considered whether insufficient atropine/oxime therapy or inappropriate supportive care (oxygen) may explain convulsions, and whether ventilatory support is necessary. Diazepam potentiates the sedative effects of other sedatives/hypnotics, including alcohol. Diazepam should not be mixed with other drugs in the same infusion solution or in the same syringe as there are numerous incompatibilities. 

The sedative and hypnotic effects of methaqualone are greatly increased when the drug is mixed with other CNS depressants such as alcohol or marijuana and can result in coma or death. 

Acetaminophen can interact with other drugs, both in good and bad ways. For example, hospitals often combine acetaminophen with the narcotic pain reliever codeine (CoTylenol ) to treat more severe pain. Caffeine can increase the effectiveness of acetaminophen similarly to the way it does with aspirin. Brand names that use a combination of aspirin, caffeine, and acetaminophen include Excedrin and Vanquish . Combining these ingredients for their additive effects also reduces the dose needed for each one and thereby reduces the risk of side effects. However, there are a few drugs that should not be mixed with acetaminophen. These include anticonvulsants and alcohol, both of which increase the risk of liver damage. 

Because Rohypnol is banned in the United States, there is an emerging trend for young people to start abusing two other Rohypnol-like drugs that are still legal in the United States clonazepam (Klonopin ) and alprazolam (Xanax). Both Klonopin and Xanax are benzodiazepines that are used for the treatment of anxiety and insomnia. Although they are less potent than Rohypnol, they can produce similar effects when mixed with alcohol and also have been reported to enhance the effects of heroin. 

The policy documents advocating the setting up of specialist multidisciplinary teams, whether they are concerned with mentally-handicapped people, alcohol, or other drug misusers, all made recommendations regarding catchment area and staffing. In practice, the teams which have been set up have been found to vary so much in size, disciplinary mix, and population served, that it is difficult to know what is actually meant by the terms CMHT, CAT, or CDT. 

As GBL and related drugs are powerful sedatives that depress brain function and respiration, they are especially dangerous when mixed with alcohol or other drugs with similar effects. They can cause seizures and are more deadly when mixed with ecstasy or other club drugs that excite the nervous system. On the club scene or at raves, combining these drugs is unfortunately a common practice. 

Methamphetamine is often combined with other illegal drugs. A common combination is mixing methamphetamine with heroin, either in an injection or in smoking. This mixture is called a speedball. Methamphetamine users will also mix in cocaine to increase the initial rush. Methamphetamine addicts are often alcoholics. 

Mixed with alcohol and other sedatives, their hazards multiply, and unintentional fatalities are possible. Successful suicides involving BZs, especially those drugs prescribed as sleeping medications—Halcion, Dalmane, and Restoril—are much more frequent than commonly realized by physicians. 

Microemulsions are fluid, transparent, thermodynamically stable oil and water systems, stabilized by a surfactant usually in conjunction with a cosurfactant that may be a short-chain alcohol, amine, or other weakly amphiphilic molecule. An interesting characteristic of microemulsions is that the diameter of the droplets is in the range of 100-1000 A, whereas the diameter of droplets in a kinetically stable macroemulsion is 5000 A. The small droplet size allows the microemulsion to act as carriers for drugs that are poorly soluble in water. The suggested method of preparation of microemulsions is as follows the surfactant, oil, and water are mixed to form a milky emulsion and titrated with a fourth component, the cosurfactant,... 

It is particularly important, while taking these drugs, that you do not mix this medical use with the recreational use of alcohol or other drugs. The effects of prescriptive medication (tranquilizers, for example) can be amplified by additional substance use (taking another depressant like alcohol, for example), and the interaction can be dangerous in unpredictable ways."... 

Increased risk when mixed with alcohol or other drugs... 

OTHER COMMENTS used as a solvent for waxes, oils, fats, gums, perfumes, and alkaloids an excellent solvent for nitrocellulose when mixed with alcohol useful in organic syntheses, especially as a reagent in Grignard and Wurtz type reactions used in the production of drugs of abuse, in the manufacture of gun powder, and as a primer for gasoline engines applications as an extractant of hormones, etc. from plant and animal tissues has also been used as an anesthetic. 

Traditional Medicine. The shrub is the source of the drug, vasaka, which is well known in the traditional medicine for bronchitis. The drug comprises fresh or dried leaves, mixed with stems or other aerial parts, and is employed as fresh juice, decoction, and infusion and in powder form also given as alcoholic extract, liquid extract, or syrup. The leaves, flowers, fruits, and roots are extensively used for treating cold, cough, whooping... 

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