Acute myeloid leukemia cell

Bailly, J. D., Muller, C., Jaffrezou, J. P., Demur, C., Cassar, G., Bordier, C., and Laurent, G., 1995, Lack of correlation between expression and function of P-glycoprotein in acute myeloid leukemia cells. Leukemia 9 799-807. 

Murphy M, Ahn J, Walker KK (1999) Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. Genes Dev 13 2490-2501 Nakajima H, Kim YB, Terano H, Yoshida M, Horinouchi S (1998) FR901228, a potent antitumor antibiotic, is a novel histone deacetylase inhibitor. Exp Cell Res 241(1) 126-133 Nebbioso A, Clarke N, Voltz E, Germain E, Ambrosino C, Bontempo P, Alvarez R, Schiavone EM, Eerrara F, Bresciani F, Weisz A, de Lera AR, Gronemeyer H, Altucci L (2005) Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells. Nature Med 11 77-84... 

Orsolie N, Golemovie M, Quintas-Cardama A et al. Adaphostin has significant and selective activity against chronic and acute myeloid leukemia cells. Cancer Sci 2006 97 952-960. 

Estrov Z, Shishodia S, Faderl S, Harris D, Van Q, Kantarjian HM, Talpaz M, Aggarwal BB. 2003. Resveratrol blocks interleukin-1 beta-induced activation of the nuclear transcription factor NF-kB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells. Blood 102 987-995. 

CIO. Cozzolino, F., Rubartelli, A., Aldinucci, D., Sitia, R., Torcia, M., Shaw, A., and Di Guglielmo, R., Interleukin 1 as an autocrine growth factor for acute myeloid leukemia cells. Proc. Natl. Acad. Sci. U.SA. 86, 2369-2373 (1989). 

Secchiero P, Zerbinati C, di Iasio MG et al (2007) Synergistic cytotoxic activity of recombinant TRAIL plus the non-genotoxic activator of the p53 pathway Nutlin-3 in acute myeloid leukemia cells. Curr Drug Metab 8 395 103... 

O., Overcoming MDR-associated chemoresistance in HL-60 acute myeloid leukemia cells by targeting sphingosine kinase-1, Leukemia, 20 (2006) 95-102. 

Bone marrow adherent layers inhibit apoptosis of acute myeloid leukemia cells. Exp. Hematol. 22 1252-1260. 

Wang, L.-M. Kucera, G.L. Capizzi, R.L. Purification and characterization of deoxycytidine kinase from acute myeloid leukemia cell mitochondria. Biochim. Biophys. Acta, 1202, 309-316 (1993)... 

To increase throughput and eliminate sample cross contamination, which is common when analyzing cells sequentially, Munce et al. [22] developed a microfluidic device with four parallel CE channels. Calcein-labeled acute myeloid leukemia cells were selected and transported with optical tweezers to injector structures at the entrance of each channel, as shown in Fig. 3a. Once loaded, the cells were lysed by the combined action of an applied electric field and the reduction in channel cross section (Fig. 3b). The injector design also enabled stepwise lysis of the cell, shown in Fig. 3c, where only the cytoplasmic material (containing calcein AM in green) was injected into the capillary, while the nucleus (stained blue with Hoechst 33342) remained in the injector structure. This selective lysis is especially useful to separate the cytoplasm from the... 

L. Chan, D. Nesbeth, T. Mackey, J. Galea-Lauri, J. Gaken, R Martin, M. Collins, G. Mufti, F. Farzaneh and D. Darling, Conjugation of lentivirus to paramagnetic particles via nonviral proteins allows efficient concentration and infection of primary acute myeloid leukemia cells. /. Virol., 79,13190-13194 (2005). 

Chen, Handong Sun and Saijuan Chen reported that Eriocalyxin B [15] triggered the degradation of AMLl-ETO oncoprotein, which made Eriocalyxin B a potential anti-cancer drug. The experiment result shows that acute myeloid leukemia cell line Kasumi-1 is most sensitive to eriocalyxin B. Alpha methylene cyclopentanone also makes eriocalyxin B a toxicant for insect growth therefore it can be used as pesticide. 

HL-60 human acute myeloid leukemia cell line... 

Seggewiss R, Pittaluga S, Adler RL, Guenaga FJ, Ferguson C, Pilz I, Ryu B, Sorrentino BP, Young WS, Donahue RE, von Kalle C, Nienhuis AW, Dunbar CE (2006) Acute myeloid leukemia associated with retroviral gene transfer to hematopoietic progenitor cells of a rhesus macaque. Blood 107 3865-3867... 

Cancers Multiple myeloma Non-Hodgkin s lymphoma Hodgkin s disease Acute myeloid leukemia Neuroblastoma Germ cell tumors Acute myeloid leukemia Acute lymphoblastic leukemia Chronic myeloid leukemia Myelodysplastic syndrome Myeloproliferative disorders Non-Hodgkin s lymphoma Hodgkin s disease Chronic lymphocytic leukemia Multiple myeloma... 

Acute myeloid leukemia (especially white blood cell count greater than 50/mm3)... 

Han, S. S. et al., Arsenic trioxide represses constitutive activation of NF-kappaB and COX-2 expression in human acute myeloid leukemia, HL-60, J. Cell. Biochem., 94, 695, 2005. 

Torus Therapeutics GTI-2040 R2 subunit of RNR Renal cell carcinoma, acute myeloid leukemia Phase II... 

Bonnet, D. and Dick, J. (1997) Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. NatMedicine3, 730-737. 

Higuchi, M., O Brien, D., Kumaravelu, P., Lenny, N., Yeoh, E.-J. and Downing, J. (2002) Expression of a conditional AMLl-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8 21) acute myeloid leukemia. Cancer Cell 1, 63-74. 

Somervaille, T. and Cleary, M. (2006) Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia. Cancer Cell 10, 257-268. 

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