Acetic acid ethylenediaminetetraacetic

EDA reacts with formaldehyde and sodium cyanide under the appropriate alkaline conditions to yield the tetrasodium salt of ethylenediaminetetraacetic acid (24). By-product ammonia is removed at elevated temperatures under a partial vacuum. The free acid or its mono-, di-, or trisodium salts can be produced by the appropriate neutrali2ation using a strong mineral acid. This same reaction with other amines is used to produce polyamino acetic acids and their salts. These products are used widely as chelating agents. 

Knabe has introduced mercuric acetate plus ethylenediaminetetraacetic acid (EDTA) as an oxidizing agent for tertiary amines (74). The solvent employed is 1 % aqueous acetic acid. In this system, the complexed mercuric ion is reduced to elemental mercury. Knabe s studies have centered on the... 

Precipitation of Fe(IIl) compounds from acid solutions as the pH increases above 2.2 is a particular problem. Complexing agents that have been used include 5-sulfosalicylic acid and citric acid (136) dihydroxymaleic acid (137) ethylenediaminetetraacetic acid (138) lactic acid (138) blends of hydroxylamine hydrochloride, citric acid, and glucono-delta-lactone (139) nitriloacetic acid blends of citric acid and acetic acid lactic acid and gluconic acid (140). 

For the same purpose, Kelly and Bryske used paper impregnated with 0.1N disodium ethylenediaminetetraacetate (EDTA) and two mobile solvents the organic phase from a mixture of n-butanol, ammonia, water (4 1 5) and the organic phase from a mixture of n-butanol, acetic acid, water (4 1 5). Disodium EDTA (0.1N) works as well as Mcllvaine s buffer when it is used to treat the paper in the method of Walton et al. (49). A circular paper chromatographic method also using paper dampened with Mcllvaine s buffer (pH 4.5) was reported by Urx et al. (50). They used a mixture of chloroform and n-butanol (4 1) as the mobile solvent. 

ACN, acetonitrile MeOH, methanol EtOH, ethanol PrOH, propanol BuOH, butanol EtOAc, ethyl acetate ether, diethyl ether pet. ether, petroleum ether HOAc, acetic acid DCM, dichloromethane THF, tetrahydrofuran TEA, triethylamine DMF, dimethylformamide TFA, trifluoroacetic acid TCA, trichloroacetic acid EDTA, ethylenediaminetetraacetic acid contg, containing soln, solution phosph., phosphate amm., ammonium. 

Many other compounds have been included in studies on sucrose response. Most of these have been herbicides or enzyme poisons. None of the common herbicides had any positive effect on sucrose at rates up to that causing severe foliar injury. Earlier reports of response from 2-(2,4,5-trichlorophenoxy)propionic acid and 2,2-dichloropropionic acid could not be substantiated in British Guiana and Queensland. 27 Some compounds, such as 3-(p-chlorophenyl)-l,l-dimethylurea (monuron), (2,4-dichloro-phenoxy) acetic acid in soil, ethylenediaminetetraacetic acid, and leaf desiccants decreased sucrose and juice solids content. 20 Field trials with several chemicals in Trinidad showed enhanced sucrose at 14 to 28 days before harvest resulting from the application of 8 and 12 lb. (per acre) of... 

Parkash and Bansal reported the detection and determination of microgram quantities of ethylenediaminetetraacetic acid with molybdophosphoric acid by a spectrophotometric method [25]. For the detection of EDTA, 5 to 10 Amberlite IRA-400 resin beads (hydroxide form) were placed on a white spot-plate and blotted dry. One drop of sample solution was added, followed by one drop of 4% molybdophosphoric acid solution. A blue color develops if EDTA is present. For the determination, the sample solution (2 mL, containing 18.6 to 186 pg of EDTA) and 4% molybdophosphoric acid solution (3 mL) are mixed for 5 minutes and diluted to 10 mL with water or sodium acetate-acetic acid buffer solution of pH 2. The absorbance is measured at room temperature at 690 nm against a reagent blank. 

Oxidative cyclization. The final step in a synthesis of racemic ajmalicine (2) required oxidative cyclization of (I). This reaction was carried out in 2.5% aqueous acetic acid with an excess of 1 1 mercuric acelale-ethylenediaminetetraacetic acid disodium salt (EDTA, I, 373-374) followed by sodium borohydride reduction of iminium intermediates. 

Synonyms edetate sodium edetic acid tetrasodium salt EDTA tetrasodium N,N -l,2-ethanediylbis[N-(carboxymethyl)-glycine] tetrasodium salt ethylenebis(iminodiacetic acid) tetrasodium salt ethylenediaminetetraacetic acid tetrasodium salt (ethylenedinitrilo)tetraacetic acid tetrasodium salt Sequestrene NA4 tetracemate tetrasodium tetracemin tetrasodium edetate tetrasodium ethylenebis(iminodi-acetate) tetrasodium ethylenediaminetetraacetate Versene. 

Ethylenediaminetetraacetic add, disodium salt dihydrate Acetic acid (ethylenedinitrilo)tetra-, disodium salt, dihydrate (8) Glycine, N,N -1,2-ethanediylbis[N-(carboxymethyl)-, disodium salt, dihydrate (9) (6381-92-6)... 

Figure 4.1 PMl curves calculated for metal ion-chelating agents bj using computer simulation. PMI is as defined in the text. Ligand symbols Tren — tri-ethylenetetramine EDTA = ethylenediaminetetraacetic acid DTP A = diethylenetriaminepentaacetic acid CDTA = cyclohexylenedijiitrotetra-acetic acid Pen = n-penicillamine OxPen = D-penicillamine-S-S-D-penicillamine, i.e. dimer of Pen BAL = 2,3-dimercaptopropanol DFO = desferrioxamine...

Dibenzotetraaza-crowns containing N-acetic acid substituents have been prepared using ethylenediaminetetraacetic dianhydride as a starting material (method V-15) (Qin, 1986). The cyclic diamides were formed in yields of about 50%. 

Intorre and Martell (237) have also studied the formation of mixed chelate species in which the zirconium 1 1 complex with the hexa-dentate chelating ligands, ethylenediaminetetraacetic acid, iV-hydroxy-ethylethylenediaminetriacetic acid, and m7 s-cyclohexanediaminetetra-acetic acid, are shown to take up one mole of the bidentate ligands, l,2-dihydroxybenzene-3,5-disulfonate l,8-dihydroxynaphthalene-3,6-disulfonate 8-hydroxyquinoline-5-sulfonate, and acetylacetone (except ZrHEDTA), to form 8-coordinate 1 1 1 species. At least for the zir-conium-EDTA-l,2-dihydroxybenzene-3,5-disulfonate species, there is evidence for dimerization (230). Additionally, the Zr EDTA complex reacts with one mole of the bidentate ligands, 5-sulfosalicyclic acid, alizarin sulfonate, citric acid, and lactic acid to form 1 1 1 complexes tartaric acid and pyrophosphate ions form complexes which could not be identified. The zirconium-nitriloacetic acid complex in the presence of two moles of oxalic acid or l,2-dihydroxybenzene-3,5-sulfonate also forms 1 1 1 complexes in solution. 

Synonyms Acetic acid, (ethylenedinitrilo) tetra-, sodium salt Edathamil monosodium ferric salt Ethylenediaminetetraacetic acid, ferric-sodium salt Ethylenediaminetetraacetic acid, sodium ferric salt ((Ethylene dinitrilo) tetraacetato)-ferate (1-), sodium Ferisan Ferric sodium edetate Ferric sodium EDTA Sodium feredetate Sodium iron EDTA Definition Commercial prod, is the trihydrate Empiricai CioHi2FeN208 Na Properties Greenish-yel. cryst m.w. 367.08 Toxicoiogy LD50 (oral, rat) 5 g/kg mildly toxic by ing. TSCA listed... 

Perhydrol added to a soln. of tetra-Na-ethylenediaminetetraacetate in aq. NaOH, allowed to stand 24 hrs. at room temp., then acidified ethylenediaminetetra-acetic acid N,N -dioxide. Y 93%. F. e. s. A. Goeur and J. Alary, Bl. 1964, 2412. 

The nse of a high ionic strength acidic extraction solvent is required to suppress metabolic activity upon disrnption of the cell and to precipitate proteins. A metal chelator snch as ethylenediaminetetraacetic acid (EDTA) is also usually required. The use of metaphosphoric acid is the best way to extract and stabilize L-ascorbic acid, as suggested by various authors [72,78,80,81]. For this reason, the samples were extracted with 3% metaphosphoric acid-8% acetic acid-1 mM EDTA solution, which is known to limit L-ascorbic acid degradation to less than 5% [82]. 

A soln. of 3-methyl-3-azabicyclo[3.2.2]nonane in 1%-acetic acid added dropwise at 70° to the Hg2+-EDTA-complex prepared by dissolving mercuric acetate and disodium ethylenediaminetetraacetate in 1%-acetic acid, and the product isolated after 2 hrs. 4-methylaminomethylcyclohexanecarboxaldehyde. Y 75-85%. F. e. s. W. Sdineider and D. K. Pomorin, B. 105, 1553 (1972). 

A reinvestigation of the oxidation of laudanosine with mercuric acetate, using ethylenediaminetetraacetic acid as a complexing agent, allowed the isolation of papaverine methiodide and of A-methyl-3,4-dihydropapaverinium iodide (LXXVIII) in lower yield. This reaction has been extended to a series of alkyl- and aryl-substituted laudanosines to study the conformation of the heterocyclic ring 141,142). 

Carboxylic acids are used in the production of polymers, pharmaceuticals, solvents, and food additives. Industrially important carboxylic acids include acetic acid (component of vinegar, precursor to solvents and coatings), acrylic and methacrylic acids (precursors to polymers, adhesives), adipic acid (polymers), citric acid (beverages), ethylenediaminetetraacetic acid (chelating agent), fatty acids (coatings), maleic acid (polymers), propionic acid (food preservative), terephthalic acid (polymers). 

Chelants at concentrations of 0.1-0.2% improve the oxidative stability through the complexation of the trace metal ions, e.g., iron, which catalyze the oxidative processes. Examples of the chelants commonly used are pentasodium diethylenetriaminepenta-acetic acid (DTPA), tetrasodium ethylenediaminetetraacetic acid (EDTA), sodium etidronate (EHDP), and citric acid. Magnesium silicate, formed in wet soap through the reaction of magnesium and silicate ions, is another chelant commonly used in simple soap bars. All of these chelants are usually added into the neat soap prior to the drying operation. 

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