Iminodiacetic acid

Uses. The largest usage of PCl is to produce phosphonic acid, H PO, which in reaction with iminodiacetic acid and formaldehyde forms a glyphosate intermediate that is decarboxymethylated to glyphosate, an effective nonselective herbicide (see Herbicides). Phosphoms trichloride is also a convenient chlorinating reagent for producing various acyl and alkyl chlorides. 

Technetium-99m mebrofenin is an iminodiacetic acid derivative used as a hepatobiliary agent. The kit is suppHed as a single vial containing lyopbilized mebrofenin. The reconstituted kit has 18-hour usage, owing to the preservative, propylparaben. 

Phosphoproteins (various). Purified by adsorbing onto an iminodiacetic acid substituted agarose column to which was bound ferric ions. This chelate complex acted as a selective immobilised metal affinity adsorbent for phosphoproteins. [Muszyfiska et al. Biochemistry 25 6850 1986.]... 

Note The reagent can be employed on silica gel layers, which may also be impregnated, for example, with 8-hydroxyquinoline or dibenzoylmethane [3] or with 2,2 -dipyridyl or iminodiacetic acid [4] or on cellulose layers. 

Theory. Conventional anion and cation exchange resins appear to be of limited use for concentrating trace metals from saline solutions such as sea water. The introduction of chelating resins, particularly those based on iminodiacetic acid, makes it possible to concentrate trace metals from brine solutions and separate them from the major components of the solution. Thus the elements cadmium, copper, cobalt, nickel and zinc are selectively retained by the resin Chelex-100 and can be recovered subsequently for determination by atomic absorption spectrophotometry.45 To enhance the sensitivity of the AAS procedure the eluate is evaporated to dryness and the residue dissolved in 90 per cent aqueous acetone. The use of the chelating resin offers the advantage over concentration by solvent extraction that, in principle, there is no limit to the volume of sample which can be used. 

Cadmium liquid amalgam 412 Cadmium sulphate, thermal analysis 498 Calcein (fluorescein iminodiacetic acid) ... 

Polymerizations of S and MMA with in situ catalyst formation have also been carried out. Matyjaszewski et a ..355 reported on the use of FeBr2 together with various ligands such as PfQHs). , NiCiIIo. and 133 alone or in combination. The use of diearboxylic acid (iminodiacetic acid, isophthalic acid)356 and methanimine ligands " for MMA polymerization has also been reported. 

N-Nitro-Iminodiacetic Acid 1 -bis-[2,4-Dinitro Anilide]. Cl6H12N8Ol2,... 

Sol in nitrobenz and dil KOH. Prepd by reacting iminodiacetic acid-dianillde with anhydr nitric acid at the fr p of the reactants Ref 1) Beil 12,(364)... 

Prepd by briefly heating iminodiacetic acid with anhydr nitric acid... 

Nitroiminodiacetic Acid Diamide (Nitrodiglycol-amidic Acid). C4H8N404,02N.N(CH2.C0.NH2)2, mw 176.16, N 31.81%, OB to C02 -72.66%, clear platelets, mp 190-218° (decompn). Prepd by nitration of iminodiacetic acid amide with anhydrous nitric acid at RT Ref 1) Beil 4, (488)... 

EDTA begins to decompose at only 400 psig (441 °F, 27.5 bar, 227 °C). However, the initial decomposition products are weaker chelants, hydroxyethyliminodiacetic acid (HEIDA) and iminodiacetic acid (IDA), so chelation still takes place. (Hydrolysis of HEIDA then continues at a much slower rate to produce more IDA and ethylene glycol.) Despite this reversion problem, EDTA is effective and, in practice, is employed at up to 1,200 psig (82.7 bar) and up to 1,500 psig (103.4 bar) when employed as an overlay product. 

A very useful, but difficult, case has been reported by Smith and Barclay (1992) for the recovery of Monsanto s highly successful herbicide, glyphosphate (N-phosphonomethyl-glycine, tradename Roundup), from an aqueous waste stream. This stream contains a lot of unwanted products like HCHO, HCOOH, aminomethylphosphoric acid, and N-phosphonomethyl iminodiacetic acid (PMIDA). The removal of PMIDA and HCOOH from glyphosphate is essential as HCOOH can react to give the formyl derivative. Amberlite IRA-93 and Amberlite IRA-68 (anionic resins) were chosen to separate glyphosphate from PMIDA and HCOOH, respectively (HCHO does not get adsorbed). 1500 recovery cycles were tried, and the resin has two years plant life scale-up with a factor of 90,000 was very successful. 

---