Well-founded

When the estimates are well founded, the skewness may be preserved by using a distribution such as the Gompertz. The median of that curve occurs a.sy = 0.5 c, while the point of inflexion corresponds to the mode at y = c/exp (1) = 0.3679 c. The statistician Karl Pearson suggested as a simple measure of skewness... 

This theory has stimulated activity in two main directions, suggestions for changes in detail in the steps of processes for particular alkaloids, and work on laboratory syntheses of known alkaloids, using the reactions specified and operated under conditions which might obtain in a plant, i.e., under what are now described as physiological conditions. All the results indicate that the theory is well-founded, and it seems possible that a technique may eventually be found by which the process may be observed in operation, direetly or indirectly, in situ, say in a solanaceous plant. 

Wohlbefinden, n. good health, wohl-begriindet, p.a. well-founded, -behalten, p.a. in good condition, -bekannt, p.a. well-known. -beleibt, p.a. corpulent. Wdhlbelelbtheit, /. corpulence, wobl-belesen, p.a. well-read, -besetzt, p.a. well-filled. -bewusst, p.a. well-known conscious, -definiert, p.a. well-defined, -er-fahren, p.a. experienced. 

The initial rejection of the efficient heat pump by many consumers may be well founded or not. In addition to the sound economic rationales for rejection, there may be market-impediment explanations. Consumers may have imperfect information and be unaware of the energy savings of new, efficient technologies. The transaction cost of accjuiring information and making an efficient choice may be just too high. Because of these impediments, households often fail to make investments that would actually save them money over time. 

The Fundamental Principle. The engineer as a professional is dedicated to improving competence, service, fairness, and the exercise of well-founded judgment in the practice of engineering for the public, employers, and clients with fundamental concern for the public health and safety in the pursuit of this practice. 

Various in situ and ex situ methods have been used to determine the real surface area of solid electrodes. Each method10,15 32 67,73 74 218 is applicable to a limited number of electrochemical systems so that a universal method of surface area measurement is not available at present. On the other hand, a number of methods used in electrochemistry are not well founded from a physical point of view, and some of them are definitely questionable. In situ and ex situ methods used in electrochemistry have been recently reviewed by Trasatti and Petrii.73 A number of methods are listed in Table 3. 

We have already met carbon dioxide, C02, many times throughout this book. It is formed when organic matter burns in a plentiful supply of air and during animal respiration. It is normally present in the atmosphere but there is widespread and well-founded concern that an increase in atmospheric carbon dioxide due to the combustion of fossil fuels is contributing to global warming (Box 14.2). 

The six parameters cannot be rigorously evaluated by use of the x-ray data alone. We consequently resort to a treatment involving the elimination of some of them by invoking a few well-founded assumptions. The... 

The study of composite materials containing both conducting polymers and other polymeric systems attracts much interest because there are well-founded expectations of improving mechanical, electrical or other properties Obviously, the... 

The existence of the ground state, which is well founded on... 

In the estimation of the approximation error the well-founded choice of the norm depends on the structure of an operator and needs investigation in every particular case. A precise relationship between an operator and a norm in the process of searching the error of approximation will be established in the general case in Section 4. Its concretization for the example of interest leads naturally to the appearance of the negative norm ... 

Some preliminary information on economical schemes. One of the most important issues in numerical methods is the well-founded choice of economical computational algorithms, the realization of which requires a min-... 

Let us stress that the well-founded choice of the regularize - R is in complete agreement with an approved principle governing what can happen and depends on the range of situations to be considered. This is certainly so with two-layer and three-layer schemes and, therefore, one and the same regularizer R could be useful and perceived to be useful for different operators A. 

However, some progress may be achieved in reducing the total number of operations by making the well-founded choice of the initial approximation,... 

Of special interest is the well-founded choice of the operator D under the agreement that the appropriate matrix D is diagonal ... 

It is important that the employment of the mouse bioassay and the interpretation of its results take these factors into consideration to ensure that the data produced are as reliable as possible and that the eventual conclusions are well founded. 

Once the equation was well founded it became a tool for establishing a scale of resonance parameters based uniformly on infrared intensities, and particularly for measuring values of substituents which had not been obtained in other ways. It should, of course, be noted that the above equation could not give the sign of for any given substituent, since... 

There is now a well-founded scepticism about the formal oxidation number, as there is experimental and theoretical evidence that in many chemical compounds these formal oxidation numbers have little correlation with the charge distribution in the molecule. Notwithstanding this, the formal oxidation number stiU has great popularity because ... 

These are well-founded basic physico-chemical principles applied to molecules adsorbed at solid surfaces, but what is new is that they have been made relevant to understanding chemical reactivity by our experimental... 

The octet principle, primitive as it may appear, has not only been applied very successfully to the half-metallic Zintl phases, but it is also theoretically well founded (requiring a lot of computational expenditure). Evading the purely metallic state with delocalized electrons in favor of electrons more localized in the anionic partial structure can be understood as the Peierls distortion (cf. Section 10.5). 

Currently the main application of interest for parametric release is to replace the sterility test as a control method in appropriate cases (given the limited value of that test to predict sterility assurance due to statistical considerations, although it is also pointed out that a sterility test provides a final opportunity to identify a major failure, although other means should provide a more reliable way of detecting such failures). The concept is applicable to well-founded methods of sterilization where the product stability is known and development data have identified the critical process parameters. The measured parameters should be such as to ensure that correct processing of the batch provides sufficient assurance that the sterility assurance level intended has been achieved. 

Pesticides were massively used, especially in the first decades after WWII, thus becoming one of the largest risk factors to human life and health, as well as to the entire natural environment. In 1962, Rachel Carson [2] described the terrible consequences of using pesticides in a way that the general public could understand for the first time. She also showed the most important difference between pesticides and other pollutants pesticides are not production waste, but are introduced into the environment deliberately. For the first time, the well-founded hypothesis was stated that, with time, poisonous and foreign chemical substances could make the Earth uninhabitable. 

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