Verdine

Sodium iodide [7681-82-5] M 149.9, m 660 , b 1304 , d 3.67. Crystd from water/ethanol soln and dried for 12h under vacuum, at 70 . Alternatively, dissolved in acetone, filtered and cooled to -20°, the resulting yellow crystals being filtered off and heated in a vacuum oven at 70 for 6h to remove acetone. The Nal was then crystd from very dilute NaOH, dried under vacuum, and stored in a vacuum desiccator [Verdin Trans Faraday Soc 57 484 1961]. [Pg.472]

Williams SA, Chen LF, Kwon H, Fenard D, Bisgrove D, Verdin E, Greene WC. Prostratin antagonizes HIV latency by activating NF-kB. J Biol Chem 2004 279 42008-17. [Pg.119]

Emiliani S, Van Lint C, Fischle W, Paras P Jr, Ott M, Brady J, Verdin E (1996) A point mutation in the HIV-1 Tat responsive element is associated with postintegration latency. Proc Natl Acad Sci USA 93(13) 6377-6381... [Pg.111]

Emiliani S, Eischle W, Ott M, Van Lint C, Amelia CA, Verdin E (1998) Mutations in the tat gene are responsible for human immunodeficiency virus type 1 postintegration latency in the U1 ceU line. J Virol 72(2) 1666-1670... [Pg.111]

Fischle W, EmUiani S, Hendzel Ml, Nagase T, Nomura N, Voelter W, Verdin E (1999) A new family of human histone deacetylases related to Saccharomyces cerevisiae HDAlp. J Biol Chem 274(17) 11713-11720... [Pg.111]

Mahmoudi T, Parra M, Vries RG, Kauder SE, Verrijzer CP, Ott M, Verdin E (2006) The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter. J Biol... [Pg.114]

WUliams SA, Chen LE, Kwon H, Ruiz-Jarabo CM, Verdin E, Greene WC (2006) NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. EMBO J 25(1) 139-149... [Pg.117]

P. Marschner and D. E. Crowley, Phytosiderophores decrease iron stress and pyo-verdine production of Pseudomonas fluorescens PF-5 (PVD-INAZ). Soil Biol. Biochem. 56 1275 (1998). [Pg.258]

Verdin A, Sahraoui ALH, Newsam R, Robinson G, Durand R (2005) Environ Pollut 133 283... [Pg.239]

Structural studies of the chromatin organization of integrated HlV-1 have identified two DNase 1-Hypersensitive Sites (HS4 and HS7) outside of the promoter/enhancer region in U3, that were likely to play a role in controlling viral transcription by virtue of their accessibility in chromatin (Fig. la and lb) (Verdin, 1991). [Pg.383]

Analysis of the chromatin organization of integrated HIV-1 identified a single major nuclease-hypersensitive site in the 8 kb region located between the two LTRs (Verdin, 1991 Van Lint et al, 1994). This hypersensitive site, centered around nt... [Pg.385]

Bisgrove D, Lewinski M, Bushman F, Verdin E (2005) Molecular mechanisms of HIV-1 proviral latency. Expert Rev Anti Infect Ther 3 805-814... [Pg.390]

Dorr A, Kiermer V, Pedal A, Rackwitz HR, HenUein P, Schubert U, Zhou MM, Verdin E, Ott M (2002) Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain. EMBO J 21 2715-2723... [Pg.391]

Sgarbanti M, Borsetti A, Moscufo N, Bellocchi MC, Ridolfi B, Nappi F, Marsili G, Marziali G, Coccia EM, Ensoli B, Battistini A (2002) Modulation of human iimnunodeficiency virus 1 replication by interferon regulatory factors. 1 Exp Med 195 1359—1370 Sheridan PL, Mayall TP, Verdin E, Jones KA (1997) Histone acetyltransferases regulate HlV-1 enhancer activity in vitro. Genes Dev 11 3327—3340... [Pg.395]

Van Lint C, Ghysdael J, Paras P Jr, Bumy A, Verdin E (1994) A transcriptional regulatory element is associated with a nuclease-hypersensitive site in the pol gene of human immunodeficiency virus type 1. J Virol 68 2632-2648... [Pg.395]

Van Lint C, Emiliani S, Ott M, Verdin E (1996a) Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation. EMBO J 15 1112-1120 Van Lint C, Emiliani S, Verdin E (1996b) The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation. Gene Expr 5 245-53 Van Lint C, Amelia CA, Emiliani S, John M, Jie T, Verdin E (1997) Transcription factor binding sites downstream of the human immunodeficiency virus type 1 transcription start site are important for vims infectivity. J Virol 71 6113-6127... [Pg.395]

Van Lint C, (2000) Role of chromatin in HIV-1 transcriptional regulation. Adv Pharmacol 48 121-160 Verdin E (1991) DNase I-hypersensitive sites are associated with both long terminal repeats and with the intragenic enhancer of integrated human immunodeficiency vims type 1. J Virol 65 6790-6799... [Pg.395]

Verdin E, Paras P Jr, Van Lint C (1993) Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation. EMBO J 12 3249-3259... [Pg.396]

EenrickR, Hiebert SW (1998) Role of histone deacetylase in acute leukemia. J Cell Biochem 31 194—202 Eischle W, Kiermer V, Dequiedt E, Verdin E (2001) The emerging role of class 11 histone deacetylases. Biochem Cell Biol 79 337-348... [Pg.423]

Richon VM, Emihani S, Verdin E, Webb Y, Breslow R, Rifkind RA, Marks PA (1998) A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases. Proc Natl Acad... [Pg.426]

Steven D. Bruner received his B.S. degree from Boston College working in the laboratory of Marc Snapper. He received a Ph.D. degree in chemistry in 2000 from Harvard University under the direction of Professor Gregory Verdine. From 2000 to 2003, he was a Damon Runyon Cancer Research postdoctoral fellow in the laboratory of Professor Christopher Walsh at Harvard Medical School. In 2003, he joined the faculty in the Department of Chemistry at Boston College as an assistant professor. Research in his laboratory focuses on the use of structural biology and synthetic chemistry to characterize natural product biosynthetic enzymes. [Pg.655]

Dow, L.K., Jones, D.N., Wolfe, S.A., Verdine, G.L., and Churchill, M.E.A. (2000) Structural studies of the high mobility group globular domain and basic tail of HMG-D bound to disulfide cross-linked DNA. Biochemistry 39, 9725-9736. [Pg.127]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...