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Interferon regulatory factor

Honda K, Takaoka A, Taniguchi T (2006) Type I interferon gene induction by Hie interferon regulatory factor family of transcription factors. Immunity 25 349-360... [Pg.646]

IP4 Inositol tetrakisphosphate IPF Idiopathic pulmonary fibrosis IPO Intestinal peroxidase IpOCOCq Isopropylidene OCOCq I/R Ischaemia-reperfusion IRAP IL-1 receptor antagonist protein IRF-1 Interferon regulatory factor 1 la Short-circuit current ISCOM Immune-stimulating complexes... [Pg.283]

A recent report has demonstrated that the proteolytic activity of NS3 plays an additional role in viral infection, beyond polyprotein processing. An important mediator of the cellular immune response is the transcription factor interferon regulatory factor 3 (IRF-3), which becomes activated on infection and then stimulates production of type-1 interferon and other antiviral genes [46]. It was found that expression of heterodimeric NS3/4A... [Pg.72]

DNA viruses modulate the host immune response, e.g., most likely the etiologic agent of Kaposfs sarcoma, KSHV (human herpes vims —8), has captured complement-binding proteins, three cytokines (two macrophage inflammatory proteins and interleukin 6), bcl-2, interferon regulatory factors, interleukin 8 receptor. Certain retroviruses... [Pg.19]

Sgarbanti M, Borsetti A, Moscufo N, Bellocchi MC, Ridolfi B, Nappi F, Marsili G, Marziali G, Coccia EM, Ensoli B, Battistini A (2002) Modulation of human iimnunodeficiency virus 1 replication by interferon regulatory factors. 1 Exp Med 195 1359—1370 Sheridan PL, Mayall TP, Verdin E, Jones KA (1997) Histone acetyltransferases regulate HlV-1 enhancer activity in vitro. Genes Dev 11 3327—3340... [Pg.395]

Research in the interferon field also led to the identification of another important family of transcription factors termed interferon regulatory factors, or IRFs. The first identified members, IRF-1 and IRF-2, are strongly inducible by the IFNs (Fujita... [Pg.5]

Nguyen, H., Hiscott, J., and Pitha, P. M. (1997). The growing family of interferon regulatory factors. Cytokine Growth Factor Rev. 8, 293-312. [Pg.11]

There may be a host of secondary transcriptional regulators, such as the IltPs, the interferon regulatory factors that could specify interferon signalling. [Pg.116]

C. ladecola. C. A. Salkowski, F. Zhang, T. Aber, M. Nagayama, S. N. Vogel, and M. E. Ross, The Transcription Factor Interferon Regulatory Factor-1 is Expressed After Cerebral Ischemia and Contributes to Ischemic Brain Injury, Journal of Experimental Medicine, 189(4) (1996) 719-727... [Pg.196]

Matsuyama T, Grossman A, Mittrucker H-W, et al. Molecular cloning of LSIRF, a lymphoid-specific member of the interferon regulatory factor family that binds the interferon-stimulated response element (ISRE). Nucleic Acids Res. 1995 23 2127-2136. [Pg.182]

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See also in sourсe #XX -- [ Pg.213 ]

See also in sourсe #XX -- [ Pg.213 ]

See also in sourсe #XX -- [ Pg.259 ]



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