Unique acceptance procedure

Tod, CEN and ISO cooperate according to the so-called Vienna Agreement of 1991 in order to save resources and to avoid duplication of work or contradictory standard methods in CEN and ISO. Both organizations agreed on basic principles, for example, on synchronized approval procedures or simultaneous publication. Standardization projects started in ISO can be transferred to CEN, if necessary, and vice versa. The transfer process can be started either by the so-called unique acceptance procedure (UAP, see Section 1.3.5) on a finalized ISO or CEN standard or by the parallel voting procedure (PVP, see Section 1.3.5) on a document qualified for an enquiry process (ISO/CEN, 2001). 

Unique acceptance procedure (UAP) The oiganization (CEN or ISO) that wants to adopt an available standard method fix)m the other organization submits it to its own adoption, voting, and pubhcation procedures. The approved standard to be transferred will be balloted at the enquiry stage of the adopting oiganization (ISO/DIS or CEN enquiry, respectively). After the positive vote the adopted document can be finalized and pubUshed. 

Ring A contracted-ring B expanded steroids of varied complexity ranging from 10(54j9H)uZ>eo-cholestan-5-one (137) to 5(10-> l)SH)flZ)eo-cholest-10(19)-ene-3j5,5a-diol 3-acetate (135) can be prepared by one of the four methods described above. In each case, the requisite starting materials can be obtained from available starting materials by way of well-developed procedures. In view of the complexity and uniqueness of the structures thus obtainable the yields must be considered acceptable. 

In addition to high sensitivity, a requirement for any acceptable analytical method is high specificity because at very low levels few confirmatory procedures can be used to establish the identity of a particular compound. A method which uniquely combines high sensitivity with high specificity is high resolution mass spectrometry. We have used this method as the basis for an approach which we believe will make possible a meaningful assessment of TCDD levels in the environment. 

Since the limit j/i —> 0 and t/2 —> 0 is not unique, we can either choose a procedure to make it unique, e.g. fix that there is always a border of an interval at z = 0, or - what is more realistic - we accept the non-uniqueness and hence an incomplete information and average over the indefinite phase in some consistent way. Leaving the phase unspecified we get... 

A sample of specified weight is normally required in the procedure. An interactive form of weighing is used, in which the display or printing unit of the entry station indicates whether or not the sample has been accepted. Before analysis it is necessary to specify the code number of the analytical method that is to be used, and to store this in the memory of the central control. To indicate where samples are located, it is necessary to identify them before weighing. Optical readers are therefore mounted on the sample-transport mechanism to register each sample. The sample is identified by a unique code placed on the outside of the sample cup. 

Some basic food analytical methods such as determination of °brix, pH, titratable acidity, total proteins and total lipids are basic to food analysis and grounded in procedures which have had wide-spread acceptance for a long time. Others such as analysis of cell-wall polysaccharides, analysis of aroma volatiles, and compressive measurement of solids and semi-solids, require use of advanced chemical and physical methods and sophisticated instrumentation. In organizing the Handbook of Food Analytical Chemistry we chose to categorize on a disciplinary rather than a commodity basis. Included are chapters on water, proteins, enzymes, lipids, carbohydrates, colors, flavors texture/ rheology and bioactive food components. We have made an effort to select methods that are applicable to all commodities. However, it is impossible to address the unique and special criteria required for analysis of all commodities and all processed forms. There are several professional and trade organizations which focus on their specific commodities, e.g., cereals, wines, lipids, fisheries, and meats. Their methods manuals and professional journals should be consulted, particularly for specialized, commodity-specific analyses. 

Instruments must be calibrated to the appropriate site instrument calibration procedure using calibration and test equipment traceable to accepted national or international standards. Calibration procedures should be produced for each unique type of instrument. An instrument calibration procedure should ... 

Examples of some observations made and theorizing done by a scientist in a specific d-ASC would illustrate the nature of a proposed state-specific science. But this is not possible because no state-specific sciences have yet been established.f61 Also, any example that would make good sense to the readers of this chapter (who are, presumably, all in an ordinary d-SoC) would not really illustrate the uniqueness of state-specific science, if it did make sense, it would be an example of a problem that could be approached adequately from both the d-ASC and our ordinary terms of accepted scientific procedures for our ordinary d-SoC and miss the point about the necessity for developing state-specific sciences. 

There is some freedom to choose T and AV (or Az) in different ways which all yield the same L, because L is the only quantity which is uniquely determined by the ray-tracing procedure (for a preselected q value). However, when L is calculated, one also can determine which points within the actual source region contribute to the spectrometer response. Hence, an appropriate value for Az can be selected, e.g., the value which delivers 90% of the intensity accepted by the spectrometer, and this Az value then fixes the corresponding value for T. Because of their transparent interpretation the quantities T and Az are frequently used, but it should be kept in mind that it is only their product (together with q), i.e., the luminosity L, which is the fundamental quantity. 

In this guidance, we discuss specific issues unique to the electronic submission of INDs and their amendments. We have described general issues such as acceptable file formats, media, and submission procedures that are common to all submissions in the companion guidance, Providing Regulatory Submissions in Electronic Format—General Considerations, dated January 1999 (January 28,1999,64 FR 4433). 

In the example given above a small amount of Fe is added to a Pt on A1203 catalyst. The catalyst is prepared by a very unique procedure that must be strictly adhered to in order to achieve the desired results. The Pt and Fe must be in such close proximity that the CO chemisorbs on the Pt and the 02 on the Fe after which they react to form C02.3 Simply reproducing the composition will not give acceptable performance. The specific details of catalyst preparation may be confidential and are most often covered by patents and trade secrets. 

There are other minor nonequivalencies of ISO test procedures compared to ASTM standards, but for color difference the ISO Test Procedure No. 105 is unique. Those who use Colour Measurement Committee (CMC) procedures—particularly CMC 2 1 Lightness to Color ratio—claim that it facilitates a uniform description for acceptability decisions that is better than any other system in existence. These equations permit the use of a single number tolerance, DEcmc, in a nearly uniform color space. The CMC formula is a modification to the perceptibility CIELAB formula. It is fully described elsewhere in this book, but it deserves some brief notice here because, after all, it is an ISO procedure. The CMC developed the basic British Standard No. 6923, Calculation of Small Color Differences. Soon afterward, in 1989, the American Association of Textile Chemists and Colorists (AATCC) adopted AATCC Test Method 173, CMC Calculation of Small Color Differences for Acceptability. Ford Motor Company indicated a preference for using CMC 2 1 ratio color difference for plastics weathering data for plastics interior trim materials. 

---