U S National Cancer Institute

We gratefully acknowledge financial support from the U.S. National Cancer Institute, Research Grant CA 13786 for some of the wotk described in this chapter. 

Transformation Assays of Established Cell Lines Mechanisms and Application. (Kakunaga, T. and Yamasaki, H., Eds). Proceedings of a Workshop Organized by IARC in Collaboration with the U.S. National Cancer Institute and the U.S. Environmental Protection Agency, Lyon 15-17 Feb. 1984. IARC Scientific Publication No. 67. 

We thank U.S. National Cancer Institute (NCI Grant No. IROICA 90265) and Arizona Biomedical Research Commission for the financial support for some of the work reviewed. AALG is thankful to his... 

We thank the U.S. National Science Foundation (NSF Grant No. ENV75-20802, the U.S. National Cancer Institute (NCI Contract No. NOI-CP-45623), the U.S. Environmental Protection Agency (EPA Contract No. 68-02-2362 and 68-02-2312), and the U.S. National Institute for Occupational Safety and Health (NIOSH Contract No. 210-77-001) for financial support. Any opinions, findings, conclusions, or recommendations expressed in this paper are those of the authors, and do not necessarily reflect the views of the NSF, NCI, EPA, and/or NIOSH. 

FIGURE 4-5 Survival of mice exposed toPS. Data from U.S. National Cancer Institute.13... 

Since the 1950s, using a different approach, the U.S. National Cancer Institute, as well as agencies in other countries, has sought to find natural anticancer compounds in plants, fungi, microorganisms, and marine invertebrates. Among these are many antibiotics that intercalate into DNA helices, e.g.,... 

After some 1000 barbituric and thiobarbituric acids had been evaluated, the U.S. National Cancer Institute found a relatively simple thiobarbituric acid, merbarone (88), which showed exceptional antineoplastic activity [431]. It exhibits good inhibitory activity against leukaemias P388 and L1210, B16 melanoma, and M5076 sarcoma by either the i.p. or oral route [431,432]. Merbarone induces DNA damage but does not inhibit RNA or protein synthesis [432]. The structure of merbarone could be postulated as assuming a... 

Research on kallikreins in Dr. Diamandis s laboratory has been funded in part by grants from the U.S. National Cancer Institute, the Early Detection Research Network, the Canadian Institutes of Health Research, the National Cancer Institute of Canada, the Natural Sciences and Engineering Research Council of Canada, and IBEX Technologies Inc., Montreal, Canada. 

Gold, L.S., Slone, T.H., Manley, N.B., Garfinkel, G.B., Hudes, E.S., Rohrbach, L., and Ames, B.N., The carcinogenic potency database analyses of 4000 chronic animal cancer experiments published in the general literature and by the U.S. National Cancer Institute/National Toxicology Program, Environ. Health Perspect., 96, 11-15, 1991. 

U.S. National Cancer Institute. Bioassay of Dichlorovos for Possible Carcinogenicity. NCI Carcinogenesis Technical Report Series No. 10. Washington, D.C. U.S. Government Printing Office,... 

El has been investigated in anticancer clinical trials at the U.S. National Cancer Institute (NCI), particularly for the treatment of myeloid leukemia (66, 67). However, its side effects still remain an issue. Thus, the authors have continued to study new natural constituents of Cephalotaxus species and to develop new analogs on the basis of SAR studies, as presented in a review by Itokawa et al. (68). 

Rosenberg, S. Clinical Immunotherapy Studies in the Surgery Branch of the U.S. National Cancer Institute Brief Review. Cancer Treatment Review 16 (1989) Suppl. A, 115-21. 

In addition, the U.S. National Cancer Institute has published a list of carcinogens in tobacco smoke. 18 ... 

Fig. 9.2 Bone structure. Diagram of a long bone indicating the compact and cancellous structures (see text) (http //training.seer.cancer.gov/module anatomy/unit3 2 bone tissue.html funded by the U.S. National Cancer Institute s Surveillance, Epidemiology, and End Results (SEER) Program, via contract number N01-CN-67006, with Emory University, Atlanta SEER Cancer Registry, Atlanta, Georgia, U.S.A.)...

National Cancer Institute. URL http //www.cancer.gov/clini-caltrials (accessed October 2005). The U.S. National Cancer Institute s PDQ database of cancer clinical trials. Uses search forms for guiding search with drop-down boxes listing all types of cancer. Can also select type and location of trial. Advanced search form allows limiting by cancer stage or sub-type, type of treatment or intervention (drop-down box lists options), drug/s used in the trial, and active or closed trials. The treatment/intervention choices allow you to select... 

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