Toxicology program

In 1983 the National Toxicology Program (NTP) reported that ethyl acrylate produced tumors in the rodent forestomach after gavage (forced... 

Litton Bionetics, Inc., LBI Project No. 12199-02, National Toxicology Program, Contract No. NOl-ES-28, 1984. 

National Toxicology Program Technical Report Series, NPT-TR-29,186, Research Triangle Park, N.C. 

A comprehensive study of the tolerance of laboratory animals to vapors of 2-nitropropane was reported in 1952 (100). In a study pubHshed in 1979, rabbits and rats survived exposure to nitromethane for six months at 750 and 100 ppm, respectively, with no unexpected findings (101). Similarly, no compound-related effects were found for rabbits exposed to 2-nitropropane at 200 ppm or for rabbits or rats exposed at 27 ppm. Liver damage was extensive in male rats exposed at 207 ppm for six months, and hepatocellular carcinomas were observed. Subsequendy, the International Agency for Research on Cancer (lARC) found that there is "sufficient evidence" to conclude that 2-nitropropane causes cancer in rats but that epidemiologic data are inadequate to reinforce the conclusion in humans (102). The National Toxicology Program also concluded that it "may reasonably be anticipated to be a carcinogen" (103). 

Methyl Ethyl Ketone Peroxide in Dimethyl Phthalate (4TT3)), National Toxicology Program, Toxicity Report Series Number 18, NIH Pubhcation 93-3341, United States Department of Health and Human Services, Washington D.C., Eeb. 1993. 

Toxicology Program (NTP) and International Agency for Research on Cancer (lARC) do not Hst 1-propanol as a carcinogen (43). ... 

National Toxicology Program, Fiscal Year 1989 HnnualPlan, U.S. Dept, of Health and Human Services, Washington, D.C., 1989, pp. 48, 83. 

The National Toxicology Program (NTP) reported on tests on mice and rats that there was an increase in the spontaneous incidence of benign tumors in male and female rats and an increase in malignant Hver and lung tumors in B6C3E1 mice. NTP concluded that these data demonstrated clear evidence of carcinogenicity in mice and female rats and some evidence in male rats (35). 

Toxicology and Carcinogenesis Studies of Chloroethane (ethyl chloride) in Rats and Mice., Report NTP/346, The National Toxicology Program, 1989. 

Dichloroethylene was selected in April 1990 for National Toxicological Program (NTP) carcinogenesis studies there is no data available as of summer 1992. 

Carcinogenesis Bioassay of Trichloroethylene in F344 Rats and B6C3F1 Mice, NTD 81—84 NIH Pubheation No. 82—1799, National Toxicology Program... 

National Toxicology Program Technical Report, National Institutes of Health pubheation number 88-2582, U.S. Department of Health and Human Services, PubHc Health Service, National Institutes of Health, Washiagton, D.C., 1987. 

Visithttp //ntp-support.niehs.nih.gov/Main Pages/Chem-HS.html. This is the site for the National Institute of Environmental Health Science. You will find MSDS-type chemical health and safety information from the National Toxicology Program. Chemical searches can be performed by chemical name, synonym, or CAS (Chemical Abstract Service) number. 

Contains information drawn from data compiled by the National Toxicology Program (NTP), which coordinates and provides information about potentially toxic chemicals with potential for human exposure to regulatoiy and research agencies. Contains information on 2,280 chemicals drawn from literature. The records closely resemble an MSDSformat. Print, CD-ROM and online interactive versions available from the Coast Guard and commercial sources. 

A super list of world-wide sources of information about drugs, pesticides, environmental pollutants and other potential toxins. Ties into ASDTR, EPA, the National Toxicology Program Carcinogen List (NTPA), and other governmental... 

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