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Transcutaneous immunization

Ghoreishi M. Dutz JP Tolerance induction by transcutaneous immunization through ultraviolet-irradiated skin is transferable through CD44-CD254- T regulatory cells and is dependent on host-derived IL-10. J Immunol 2006 176 2635-2644. [Pg.100]

Baca-Estrada, M. E., et al.. Effects of lL-12 on immune responses induced by transcutaneous immunization with antigens formulated in a novel lipid-based biphasic delivery system. Vaccine, 18, 1847-54, 2000. [Pg.16]

Transcutaneous immunization is a new technique in which vaccine antigens in a solution are applied on the skin to induce an antibody response without systemic or local toxicity [48]. The primary advantage of transcutaneous immunization is the presentation of immunogens to antigen presenting cells (APCs) within the skin, specifically Langerhans cells that are highly... [Pg.321]

The authors also demonstrated that low-frequency ultrasound acts as a transcutaneous immunization adjuvant that eliminates the requirement of toxins to elicit an immune response. Delivery of as little as 1.3 p.g of tetanus toxoid by low-frequency ultrasound generated an immune response comparable to that induced by 10 pg subcutaneous injection. [Pg.323]

Gockel, C.M., S. Bao, and K.W. Beagley. 2000. Transcutaneous immunization induces mucosal and systemic immunity A potent method for targeting immunity to the female reproductive tract. Mol Immunol 37 537. [Pg.329]

Glenn, G.M., et al. 1998. Transcutaneous immunization with cholera toxin protects mice against lethal mucosal toxin challenge. J Immunol 161 3211. [Pg.329]

Tezel, A., et al. 2005. Low-frequency ultrasound as a transcutaneous immunization adjuvant. Vaccine 23 3800. [Pg.329]

O Farrel, C. Transcutaneous immunization more effective non-invasive vaccines. Inn. Pharm. Tech. 2000, (1), www. iptonline.com. [Pg.1325]

Scharton-Kersten, T. Yu, J.M. Yassell, R. O Hagan, D. Alving, C.R. Glenn, G.M. Transcutaneous immunization with bacterial ADP-ribosylating exotoxins, subunits, and umelated adjuvants. Infect. Immun. 2000, 68, 5306-5313. [Pg.2754]

Transdermal vaccination or transcutaneous immunization, is attractive, because it does not require specially trained personnel necessary for needle injections. Topical application of antigens to intact skin has shown promising results for the administration of DNA-based vaccines. Noninvasive gene delivery by pipetting adenovirus- or liposome-complexed plasmid DNA onto the outer layer of skin was able to achieve localized transgene expression within a restricted subset of skin in mice. It also elicited an immune response against the protein encoded by the DNA. ... [Pg.3919]

Scharton-Kersten, T.M. Glenn, G. Vassell, R. Yu, J. Walwender, D. Alving, C.R. Principles of transcutaneous immunization using cholera toxin as an adjuvant. Vaccine, Suppl 17 1999, 2, s37 3. [Pg.3927]

Vaccines for the Treatment of Diseases of Farmed Animals, Application of DNA Vaccine Technology to Aquaculture, Transcutaneous Immunization of Domestic Animals,... [Pg.299]

Hammond SA, Walwender D, Alving CR, Glenn GM (2001) Transcutaneous immunization T cell responses and boosting of existing immunity. Vaccine 19(17-19) 2701-2707... [Pg.137]

Transcutaneous and other routes of immunization immune adjuvants (cMIA I and II) mixed with Newcastle-disease vaccine ... [Pg.197]

Fig. 3 (A) PLGA microneedle (MN) arrays were coated with ICMVs via layer-by-layer assembly and deposition of ICMVs was confirmed by confocal microscopy. (B) C57BI/6 mice were immunized on days 0 and 21 with microneedles coated with either OVA-containing ICMVs or soluble OVA. Control groups included OVA-containing ICMVs or soluble OVA given via intradermal injection. Microneedle-mediated transcutaneous vaccination with ICMVs ehcited > 10-fold higher anti-OVA serum IgG titers, compared with other groups. Figure reproduced from [42],... Fig. 3 (A) PLGA microneedle (MN) arrays were coated with ICMVs via layer-by-layer assembly and deposition of ICMVs was confirmed by confocal microscopy. (B) C57BI/6 mice were immunized on days 0 and 21 with microneedles coated with either OVA-containing ICMVs or soluble OVA. Control groups included OVA-containing ICMVs or soluble OVA given via intradermal injection. Microneedle-mediated transcutaneous vaccination with ICMVs ehcited > 10-fold higher anti-OVA serum IgG titers, compared with other groups. Figure reproduced from [42],...
See other pages where Transcutaneous immunization is mentioned: [Pg.60]    [Pg.328]    [Pg.322]    [Pg.1322]    [Pg.3919]    [Pg.129]    [Pg.60]    [Pg.328]    [Pg.322]    [Pg.1322]    [Pg.3919]    [Pg.129]    [Pg.184]    [Pg.135]   
See also in sourсe #XX -- [ Pg.129 ]



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