Immune response inducing

Katsutani, N., and Shionoya, H., Drug-specific immune responses induced by immunization with drugs in guinea pigs and mice. J. Toxicol. Sci., 17, 169, 1992. 

Baca-Estrada, M. E., et al.. Effects of lL-12 on immune responses induced by transcutaneous immunization with antigens formulated in a novel lipid-based biphasic delivery system. Vaccine, 18, 1847-54, 2000. 

Koning, F. (2008). Celiac disease Sandwiched between innate and adaptive immune responses induced by gluten. J. Pediatr. Gastroenterol. Nutr. 46(Suppl. 1), E8-E9. 

Tabata, Y., Inoue, Y., and Ikada, Y. Size effect on systemic and mucosal immune responses induced by oral administration of biodegradable microspheres. Vaccine 14 1677-1685, 1996. 

R7. Reinherz, E. L., and Schlossman, S. F., Current concepts in immunology Regulation of the immune response—Inducer and suppressor T-lymphocyte subsets in human beings. N. Engl. J. Med. 303, 370-373 (1980). 

BenMohamed, L., Belkaid, Y., Loing, E Brahimi, K Gras-Masse, H., and Druilhe, P. (2002) Systemic immune responses induced by mucosal administration of lipopeptides without adjuvant. Eur. J. Immunol. 32(8), 2274-2281. 

Reveneau, N., Goeffroy, M. C., Locht, C., Chagnaud, P., and Mercenier, A. (2002), Comparison of the immune responses induced by local immunizations with recombinant... 

Microspheres Ionic gelation with tripolyphosphate Bordetella, bronchiseptica, dermonecrotoxin Chitosan In mice Systemic and mucosal immune responses induced 21... 

The toxicology study should include an evaluation of the immune response, which will provide evidence that the vaccine was dosed, show that the species is responsive to the vaccine, and might allow the correlation between a toxic effect and the immune response induced. For further details, see References 4, 15, 16, 22. 

We do not describe in details the immunological methods (immunization, Gr release assay, ELISPOT, ELISA and flow cytometry) used for the analysis of the immune responses induced by the liposome vaccines (Subheading 3.2). For comprehensive information, we refer to our publications (21-23) and to the related literature. 

Interferon 19.2 Virally infected cells Participates in the innate immune response, induces resistance to viral... 

Figure 5.2 The characteristics of divergent immune responses induced in mice by chemical respiratory and contact allergens.

A complex picture of respiratory sensitization to chemical allergens emerges where the nature of the allergen itself, the conditions under which it is encountered, the characteristics of the immune response induced and congenital and/or acquired determinants of susceptibility all impact on the likelihood of... 

In recent years there have been significant advances in the characterization of immune responses induced by chemical allergens. Despite such progress it must be acknowledged that a consensus regarding the immunobiological mechanisms that, in practice, result in respiratory sensitization has yet to be achieved. At the centre of the debate are questions regarding the importance of IgE and other homocytotropic antibody in the development of sensitization. This and other priority areas for further research are listed below. 

It remains to be established to what extent the route of exposure to chemical allergen impacts on the effectiveness of sensitization. Although there is reason to believe that sensitization of the respiratory tract can be achieved following dermal contact with an appropriate chemical allergen, it is not yet clear whether the characteristics of immune responses induced by chemical allergens in different tissue compartments vary in important respects. 

A good model to study the immune response induced by a potential vaccine is the infection of certain inbred strains of mice with L. major. Protective immunity against L. major is mediated by the expansion of a ThI subset of CD4 T lymphocytes secreting IFN-y and lL-12. 

Potentiated Disease. Vaccination can induce immune responses that establish a condition that potentiates disease upon subsequent exposure to the pathogen. Preclinical studies to evaluate adjuvanted protein-based vaccines comprising helper T cell and/or B cell epitopes from Plasmodium berghei indicated that vaccinated mice died earlier of malaria than unvaccinated control mice, a finding attributed to the immune response induced against the T cell epitope and a nonspecihc effect of the adjuvant (Reed et al., 1997). 

Many factors influence the immune response induced by therapeutic proteins. These can be divided into product, patient, and treatment characteristics, and several factors are still unknown. 

Peng S, Trimble C, He L, et al. (2006). Characterization of HLA-A2-restricted HPV-16 E7-specific CD8(-t) T-cell immune responses induced by DNA vaccines in HLA-A2 transgenic mice. Gene Ther. 13 67-77. 

Cook It is at odds with the immune response inducing these vessels in other organs. 

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