TOXLINE database

TOXLINE database (1981-current) from the U.S. National Library of... 

Columns and review sections in journals or newsletters can help the professional keep abreast of new resources or provide comparative information on established resources in selected areas. Collections of reviews are also available online in such sources as Comprehensive Core Medical Library (CCML) by Ovid Technologies, Inc., Book Review Index (online and in print) by Wilson, and the National Library of Medicine s TOXLINE database. Reviews of popular works dealing with consumer health or environmental concerns can also be found in newspapers, popular magazines, and consumer organization newsletters. Summaries and reviews of online databases and databanks can be found in the information science journals, directories of online resources, and produc-er/vendor documentation. 

In late 1966, Dwight R. Tousignaut succeeded Donald Francke as editor of IPA. IPA s production process was computerized in 1970, and IPA s first electronic licensing arrangement was formalized in 1971 in an agreement to supply magnetic tape to the National Library of Medicine for use in its ToxLine database. 

CRISP. 1995. Computer Retrieval of Information on Science Projects. Subfile of Toxline Database, National Library of Medicine, National Institutes of Health, Bethesda, MD. 

TOXLINE database, Canadian Centre for occupational health and safety, Hamilton ON, Canada, web site www.ccohs.ca. 

TOXLINE (non-royalty based) Toxicology Information Online National Library of Medicine 8600 Roekville Pike Bethesda, MD 20894 (301) 496-1131 On-line bibliographic database covering the pharmacological, physiological, and toxicological effects of drugs and chemicals. Information is taken from eleven secondary sources. 

TOXNET is a series of databases on chemical toxicity hosted by the National Institutes of Medicine, which allows multiple searching options. The databases include ChemIDplus, HSDB, Toxline, CCRIS, DART, GENETOX, IRIS, ITER, LactMed, Multi-Database, TRI, Haz-Map, Household Products and TOXMAP. 

SIS s Toxicology and Environmental Health Information Program (TEHIP) produces TOXNET (TOXNET 2007), a collection of toxicology and environmental health databases that includes, among others, the Hazardous Substances Data Bank (HSDB), a database of potentially hazardous chemicals, TOXLINE (containing references to the world s toxicology literature), and ChemIDplus (a chemical dictionary and structure database). 

The order of procedures that result in the publication of an EHC monograph is shown in the flow chart on the next page. A designated staff member of IPCS, responsible for the scientific quality of the document, serves as Responsible Officer (RO). The IPCS Editor is responsible for layout and language. The first draft, prepared by consultants or, more usually, staff from an IPCS Participating Institution, is based initially on data provided from the International Register of Potentially Toxic Chemicals and from reference databases such as Medline and Toxline. 

The virtual terminal feature is designed for asynchronous inter computer communication and provides the capability to access remote databases such as CAS On-Line, Toxline and Medline. Data stored on the local system can be sent to remote computers by either facility. 

Databases include PubMed and TOXLINE http //ntp.niehs.nih.gov/... 

PUB MED includes MEDLINE and PREMEDLINE. MEDLINE, the U.S. National Library of Medicine s premier bibliographic database, covers medicine, nursing, dentistry, veterinary medicine, health-care systems, and the preclinical sciences. The above-mentioned TOXLINE searches include MEDLINE citations. PREMEDLINE, also produced by NLM, provides citation and abstract information before full records are added to MEDLINE. 

Contains more than 14 million citations to the worldwide literature in the life sciences, environmental sciences, and experimental medicine dating back to 1969. One of the largest of the science databases. Produced by BIOSIS. Selected citations contained in a subset of TOXLINE. (Data-Star, CISTI, DIALOG, DIMDI, OVID, STN)... 

This bibliographic database contains more than 200 000 references to the literature of occupational health and safety from monographs, journals, and reports. Produced by the US National Institute for Occupational Safety and Health (NIOSH). As of 1997, NIOSH will only add NIOSH publications and articles by NIOSH authors to the database (CCINFOLINE, CIS, DIALOG, ORBIT/QUESTEL, STN, TOXLINE). 

One of the largest online bibliographic sources for toxicology information, these databases contain over 3 million citations to all areas of toxicology. TOXLINE references are drawn from various sources grouped into two parts - TOXLINE Core and TOXLINE Special. A standard search of TOXLINE retrieves records from both subsets. Users can also limit retrieval to only one. Both files are available on the NLM MEDLARS system (DIALOG on CD through Silver Platter). 

The PolTox series from Silver Platter, Inc., provides information on pollution and toxicology. PolTox I contains Aquatic Sciences and Fisheries Abstracts, Ecology Abstracts, Food Science and Technology Abstracts, Health and Safety Science Abstracts, Pollution Abstracts, RISKLINE, Toxicology Abstracts, and all of TOXLINE. PolTox II contains information derived from EMBASE and PolTox III information from the CAB Abstracts database. 

The NLM developed PubMed as a user-friendly search tool to explore MEDLINE. For each citation listed in a search result, the user has the option to click on Related Articles, which takes the user to a listing of additional citations that are related to the search topic. Additionally, PubMed offers access to publisher Web sites for full-text articles, a citation matcher (service that assists a user in finding a complete citation), and access to the molecular biology databases of the NCBI. One of the newest features of PubMed is called Cubby, a page on the site that allows the user to store a search and update it in the future (users need to register for this free service). AIDSLINE soon will be added to PubMed. A user can search MEDLINE and 14 other NLM databases (e.g., AIDSLINE, AIDSDRUGS, TOXLINE) via Internet... 

TOXNET http //toxnet.nlm.nih.gov User-friendly Web site that allows searching of a cluster of bibliographic and factual databases with information on toxicology and environmental health. Includes the Hazardous Substances Databank (HSDB), with detailed information about 4500 chemicals, and TOXLINE, containing >3 million citations to journal articles and technical reports. 

Most of the selected female reproductive toxicology studies examined explicitly stated chemical exposure levels either as parts per million, stratifying as to number of days of exposure, or as estimates of the percentage of the threshold limit values. Medline, Toxline, and Dissertation Abstracts databases were utilized to search for all research papers published in any language from 1966 to 1996. In total, 559 studies were obtained from the literature search. Of these, only 21 studies explicitly stated some sort of exposure level for the various chemicals. These chemical exposure levels in the literature and subsequent pregnancy outcomes were compared to lOL chemical exposure indices. The following is an example of one of the many chemical exposures encountered, namely exposure to toluene. For other compounds, Table 20.3.5 contrasts values in the literature with lOL indices of chemical exposure. 

Some official bodies publish extensive reviews of hazard data, and many common solvents are covered by the USA NIOSH Criteria Documents [2], the USA ACGIH TLV Documentation [3] and the UK HSE Criteria Document Summaries [4]. Several textbooks contain useful data [5,6], and the ultimate source of information is the open scientific literature, to which access may be gained by searching online databases, for example toxline [7]. 

The databases supplied by NLM are easy to use and relatively inexpensive. TOXLINE, the best source of information for most people, covers data published from 1981 to the present. For data published in the period from 1965 through 1980, TOXL1NE65, a back file of TOXLINE, is also available. The telephone number to call for information and instmctions on obtaining an NLM account is 1-800-638-8480. 

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