Tartrazine dyes

Contraindications Allergy to tartrazine dye, bleeding disorders, GI bleeding or ulceration, history of hypersensitivity to choline magnesium trisalicylate, aspirin, or NSAIDs. 

Fig. 5 Chemical structures of indigoid (indigotine) and azo (amaranth, allura red, black PN, and tartrazine) dyes.

Azo dyes e.g., tartrazine (dyes) Anaphylactoid reaction. Contraindicated for aspirin-intolerant individuals [7,23,70]... 

In patients with asthma or those suspected of being sensitive to aspirin, an oral challenge can be performed. This should be performed with great caution in a hospital setting with resuscitation equipment at hand. For patients known to be aspirin-sensitive, the major preventive measure is avoidance. Other agents reported to be cross-reactive with aspirin include tartrazine dye, indomethacin, and phenylbutazone. 

F. Some oral haloperidol tablets contain tartrazine dye, v ich may precipitate allergic reactions in susceptible patients. 

Smith LJ, Slavin RG (1976) Drugs containing tartrazine dye. J Allergy Chn Immunol 58 456-470... 

Acid black 63 Acid orange 92 FD C Yeiiow No. 5 Tartrazine dye, polyamides Acid green 1 dye, poiyester... 

Barros WRP, Alves SA, Franco PC, Steter JR, Rocha RS, Lanza MRV (2014) Electrochemical degradation of tartrazine dye in aqueous solution using a modified gas electrode. J Electrochem Soc 161 H438-H442... 

Vesely, M. Polackova, E. Havel, M. Janecek, M. Tartrazine dye crystal prodnctionby salting-out with sodium chloride. Czech. CS 255665, 1988 Chem. Abstr. 1989, 111, 235047. 

Many azo dyes, such as tartrazine (Section 4.04.4.1.3), are susceptible to reduction by bacterial reductases in the intestinal flora. Azo reduction is believed to proceed through a hydrazo intermediate that undergoes subsequent reductive cleavage of the nitrogen-nitrogen bond to yield the arylamine derivatives (B-80MI40406). 

Direct and derivative spectrophotometric and IP-RP-HPLC methods were applied to identify and determine synthetic dyes and follow their degradation processes. " The dyes considered were Tartrazine (E 102), Quinoline Yellow (E 104), Sunset Yellow (E 110), Carmosine (E 122), Amaranth (E 123), New Coccine (E 124), Patent Blue Violet (E 131), and Brillant Blue ECE (E 133). All are considered representative additives for soft drinks. 

Azo dyes Allura Red AC, Amaranth, Azorubine, Brilliant Black BN, Brown FK, Brown HT, Lithol Rubine BK, Ponceau 4R, Red 2G, Sunset Yellow, Tartrazine Triarylmethane (triphenylmethane) dyes Brilliant Blue FCF, Fast green FCF, Green S, Patent Blue V... 

Dyes. Dose does not appear to be a factor in patient reaction to dyes. The mandatory labeling of the azo dye tartrazine (FD C yellow No. 5) in OTC and prescription medications [58] has focused the attention of pharmaceutical manufacturers and the consumer on the potential danger of dyes in susceptible individuals. 

The yellow ink jet dyes (and pigments) are metal-free azo dyes, such as Cl Direct Yellow 132 and Cl Acid Yellow 23 (Tartrazine).48,49 Most of the magentas are azo dyes derived from H-acid (l-amino-8-naphthol-3,6-disulfonic acid), such as (62), and xanthenes, such as Cl Acid Red 52 and Cl Acid Red 289.48,49 Where high lightfastness is a requirement, a copper complex azo dye, Cl Reactive Red 23 (63), is used. However, such dyes are dull (see Section 9.12.3.2). Nickel complex PAQ dyes, such as (22), are claimed to be brighter and to have similar high lightfastness... 

Many other dyes, including tartrazines and eosines, have been made into pigments in the past for use in printing inks, in which their soft texture and bright hues were much valued. Their light fastness was generally only 1 on the ISO scale and they are now obsolete. 

In 1884, H.J. Ziegler first used pyrazolones as coupling components. In an attempt to find a new dye by synthesizing a colored osazone from phenyl hydrazine-4-sulfonic acid and dioxo tartaric acid, he obtained yellow tartrazine by condensation ... 

The electropherogams demonstrate the baseline separation of dyes even in the presence of complicated accompanying matrices such as mint syrup. The LOD and LOQ values were between 1.0 - 1.7 and 3.2 - 5.5 jUg/ml, respectively, and the RSD of migration time and peak areas ranged 1.3 - 1.8 per cent and 2.0 - 3.1 per cent. The migration times of the dyes were Tartrazine, 9.97 min Sunset yellow FCF 6.73 min Amaranth, 8.41 min New coccine, 7.49 min Allura red AC, 5.43 min Patent blue V calcium salt, 4.23 min. The amounts of synthetic dyes found in commercial samples are compiled in Table 3.38. It has been stated that the analysis time is rapid and the method makes possible the separation and determination of these dyes at ppm levels in various foodstuffs [186],... 

CZE using cyclodextrins (CD) as buffer additives has also been employed for the determination of synthetic dyes in various food products. The synthetic dyes New coccine, Erythrosine, Allura red AC, Tartrazine, Sunset yellow FCF, Brilliant blue FCF, Indigo carmine and Fast green FCF were included in the experiments. Measurements were carried out in a used-silica capillary (47 cm length, 40 cm to the detector, 50 pm i.d.). Capillary temperature was 25°C and separation voltage was 20 kV. Pressure injection was performed... 

Dyes Tartrazine and intermediates Bu N HsO-MeOH-CQiH. Octadecyl 216... 

Tartrazine was separated by ion-pair HPLC from its subsidiary dye 3-carboxy-5-hydroxy-1 -p-sulfopheny-4-phenylazo-pyrazole disodium salt (195) and from its intermediates sulfanilic acid and l-(4-sulfophenyl)-3-carboxy-5-hydroxypyrazolone (pyrazolone-T) by means of TBA hydroxide (194,212). Ion-pair chromatography was also used for the determination of free and bound nonsulfonated aromatic amines in tartrazine after reduction with dithionite, diazotization with sodium nitrite, and coupling with R-salt (202). 

Color modification Synthetic dyes Tartrazine (FD C yellow5) Sunset Yellow... 

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