Superoxide dismutases expression

Maier C. M., Sun G. H., Cheng D., Yenari M. A., Chan P. H., and Steinberg G. K. (2002) Effects of mild hypothermia on superoxide anion production, superoxide dismutase expression, and activity following transient focal cerebral ischemia. Neurobiol. Dis. 11, 28 -2. 

Bergeron C, Petrunka C, Weyer L (1996) Copper/zinc superoxide dismutase expression in the human central nervous system. Correlation with selective neuronal vulnerability. Am J Pathol... 

Zhang R, Chae S, Lee JH, Hyun JW (2012) The cytoprotective effect of butin against oxidative stress is mediated by the up-regulation of manganese superoxide dismutase expression through a PI3K/Akt/Nr 2-dependent pathway. J Cell Biochem 113(6) 1987-1997. doi 10.1002/jcb.24068... 

St Clair DK, Oberley LW. Manganese superoxide dismutase expression in human cancer cells a possible role of mRNA processing. Free Radic Res Commun 1991 12-13 771-778. 

Amstad, P.A. et at. Manganese superoxide dismutase expression inhibits soft agar growth in JB6 clone41 mouse epidermal cells. Carcinogenesis, 18 (3), 479, 1997. 

Komada E, NisUguchi K, Tanigawaia Y, Wu XY, Iwakawa S, Okumura K. Effect of transfection with a superoxide dismutase expression plasmid on xanthine/xanthine oxidase-induced cytotoxicily in cultuied rat lung cells. Biol Hiarm Bull 1996 19 1100 1102. 

Ceballos-Picot, I., Nicole, A., Briand, P., Grimber, G., Delacourte, A., Defossez, A., Javoy-Agid, F., Lafon, M., Blouin, J.L. and Sinet, P.M. (1991). Neuronal-specific expression of human copper-zinc superoxide dismutase gene in transgenic mice animal model of gene dosage effects in Down s syndrome. Brain Res, 552, 198-214. 

Values are expressed as mean (SEM) of 4-6 muscles. EDL, extensor digitorum longus SOD, superoxide dismutase. 

Kulkami-Narla A., Getchell T.V. and Getchell M.L. (1997). Differential expression of manganese and copper-zinc superoxide dismutases in the olfactory and vomeronasal receptor neurons of rats during ontogeny. J Comp Neurol 381, 31-40. 

The effectors of the mammalian host immune attack against filaria include reactive oxygen intermediates. Filarial nematodes express glutathione peroxidase, thioredoxin peroxidase and superoxide dismutase at their surface - enzymes believed to protect the nematode from this attack (Selkirk et al., 1998). A bacterial catalase gene has been identified that most probably derives from the endosymbiont genome (Henkle-Duhrsen et al., 1998) this enzyme may contribute with other enzymes to the protection of both Wolbachia and its nematode host from oxygen radicals. 

Ou, X., Tang, L., McCrossan, M., Henkle-Diihrsen, K. and Selkirk, M.E. (1995) Brugia malayi localisation and differential expression of extracellular and cytoplasmic CuZn superoxide dismutases in adults and microfilariae. Experimental Parasitology 80, 515-529. 

Gurney, M. E., Pu, H., Chiu, A. Y. etal. Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation. Science 264 1772-1775,1994. 

Wang, J., Xu, G., Gonzales, V. et al. Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site. Neurobiol. Dis 10 128-138,2002. 

Yeast expression vectors have been among those most commonly used since the beginning of gene technology. Vectors based on baker s yeast, Saccharomyces cerevisiae, have been especially popular for robust expression of many types of recombinant proteins [90]. For instance, the first commercially available recombinant vaccine, the hepatitis B surface antigen vaccine, was produced from an S. cerevisiae vector [91]. Many other recombinant proteins have also been efficiently expressed in yeast including al-Antitrypsin [92], insulin [93], Epstein-Barr virus envelope protein [94], superoxide dismutase [95] and interferon-a [90]. 

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