Possible roles

Wliat is left to understand about this reaction One key remaining issue is the possible role of otiier electronic surfaces. The discussion so far has assumed that the entire reaction takes place on a single Bom-Oppenlieimer potential energy surface. Flowever, three potential energy surfaces result from the mteraction between an F atom and FI,. The spin-orbit splitting between the - 12 and Pi/2 states of a free F atom is 404 cm When... 

Forgacs G 1995 On the possible role of cytoskeletal filamentous networks in intracellular signalling J. Ceii. Sc/. 108 2131-43... 

No mechanistic aspects of organic chemistry (or, for this reason, any reaction intermediates) were ever mentioned by Zemplen in his lectures or writings, nor did he consider or accept their existence. I never heard him mention the names of Meerwein, Ingold, Robinson, or any other pioneers of the mechanistic electronic theory of organic chemistry. The possible role of organic ions was similarly never mentioned. He was. 

A confirmation of the possible role of sulfur in the ylide stabilization by d-high rate of decarboxylation of 5-thiazoIecarboxylates (433). 

The effectiveness of theophylline in the treatment of asthma seems to result from a combination of biological properties which are not clearly understood (63). Detailed discussions of the possible role of xanthines in asthma may be found in references 64—66. 

The activity of ivermectin against the filarial parasite Dirofilaria immitis in dogs suggested a possible role for the control of filarial parasites of humans (20). It has been extensively tested in human onchocerciasis and is now considered to be the dmg of choice. In a single yearly oral dose, it suppresses microfilariae in the skin and eyes and, in most cases, prevents the progression of the disease to blindness. Table 4 shows the results of a 30-patient double-blind study recorded over one year. 

StiU another possible role of supersaturation is that it affects the solution stmcture and causes the formation of clusters of solute molecules. These clusters may participate in nucleation, although the mechanism by which this would occur is not clear. Evidence of the existence of cluster formation in supersaturated solutions has been presented for citric acid (21) while others have examined the phenomenon in greater detail (22,23). 

For any given process, one takes a qualitative look at the possible role of fluid shear stresses. Then one tries to consider pathways related to fluid shear stress that may affect the process. If there are none, then this extremely complex phenomenon can be dismissed and the process design can be based on such things as uniformity, circulation time, blend time, or velocity specifications. This is often the case in the blending of miscible fluids and the suspension of sohds. 

Possible role of the induced acidity and basicity in catalysis and environmental chemistry is discussed. The suggested mechanism explains the earlier reported promotive effect of some gases in the reactions catalyzed by Bronsted acid sites. Interaction between the weakly adsorbed air pollutants could lead to the enhancement of their uptake by aerosol particles as compared with separate adsoi ption, thus favoring air purification. 

Bl) The metrics effect is very significant in special theoretical examples, like a freely joined chain. In simulations of polymer solutions of alkanes, however, it only slightly affects the static ensemble properties even at high temperatures [21]. Its possible role in common biological applications of MD has not yet been studied. With the recently developed fast recursive algorithms for computing the metric tensor [22], such corrections became affordable, and comparative calculations will probably appear in the near future. 

The structure of vitamin E in its most active form, o-tocopherol, is shown in Figure 18.38. a-Tocopherol is a potent antioxidant, and its function in animals and humans is often ascribed to this property. On the other hand, the molecular details of its function are almost entirely unknown. One possible role for... 

Based on the information presented in the text and in Figures 25.4 and 25.5, suggest a model for the regulation of acetyl-CoA carboxylase. Consider the possible roles of subunit interactions, phosphorylation, and conformation changes in your model. 

Green-yellow salts of the tetrahedral [MX4] (X = Cl, Br, I) ions can be obtained from ethanolic solutions and are well characterized. Furthermore, a whole series of adducts [MnX2L2] (X = Cl, Br, I) are known where L is an N-, P- or A -donor ligand, and both octahedral and tetrahedral stereochemistries are found. Of interest because of the possible role of manganese porphyrins in photosynthesis is [Mn (phthalocyanine)] which is square planar. The reaction of aqueous edta with MnC03 yields... 

Is there a "universal ionic liquid at the present state of development The answer is clearly no. Many of the ionic liquids commonly in use have very different physical and chemical properties (see Chapter 3) and it is absolutely impossible that one type of ionic liquid could be used for all synthetic applications described in Chapters 5-8. In view of the different possible roles of the ionic liquid in a given synthetic application (e.g., as catalyst, co-catalyst, or innocent solvent) this point is quite obvious. However, some properties, such as nonvolatility, are universal for all ionic liquids. So the answer becomes, if the property that you want is common to all ionic liquids, then any one will do. If not, you will require the ionic liquid that meets your needs. 

It is claimed that since S, Ca and A1 will be present as precipitates they would not in general be detected as grain boundary segregants and their ineffectiveness is indicated by the brackets in equation 8.10. Lea and Hondros do not consider the possible roles of carbon or nitrogen in the cracking of their steels, but from the data obtained phosphorous had the most deleterious effects. 

It must be noted that the cyclic model fails to account for the role of the additional alkyllithium and diethylaluminum that are required in precise amounts to achieve high selectivity. A simple model that recognizes a possible role for the additional reagents suggests the intermediacy of an extended, noncyclic transition state G with the aldchydic oxygen coordinated to some undefined Lewis acidic species derived from the additional components of the reaction mixture26,44. Aggregates composed of enolate, alkyllithium and dialkylaluminum species are also possible. 

The postulation of a possible role of trace amines in the context of schizophrenia was kindled early on by the structural similarity between PEA and amphetamine. Symptoms such as hallucinations and paranoid episodes caused by a prolonged amphetamine intoxification are reminiscent of patients suffering from acute schizophrenia. Further support for a role of trace amines in the context of schizophrenia comes from clinical studies... 

In bone, three proteins have been described which are vitamin K-dependent, osteocalcin (bone Gla protein), matrix Gla protein (MGP), and protein S. Osteocalcin is synthetized by osteoclasts, regulated by the active form of vitamin D, calcitriol. Its capacity to bind calcium needs a vitamin K-dependent y-carboxylation of three glutamic acid residues. The calcium binding capacity of osteocalcin indicates a possible role in bone mineralization, but its exact function is still unclear. However, it is widely used as a serum marker for bone mineralization. Protein S, mainly a coagulant, is also vitamin-K dependent and synthesized in the liver. Children with... 

Jacobs et al. [59,925,926] (Fig. 17). While this scheme conveniently summarizes many features of the observed behaviour, a number of variations or modifications of the mechanisms indicated have been proposed. Maycock and Pai Vemeker [924,933] emphasize the possible role of point defects and suggest, on the evidence of conductivity measurements, that the initial step may be the transfer of either a proton or an electron. Boldyrev et al. [46] suggest that proton conduction permits rapid migration of HC104 within the reactant and this undergoes preferential decomposition in distorted regions. More recently, the ease of proton transfer and the mobilities of other species in or on AP crystals have been investigated by a.c. [360] and d.c. [934] conductivity measurements. Owen et al. [934] could detect no surface proton conductivity and concluded that electron transfer was the initial step in decomposition. At the present time, these inconsistencies remain unresolved. 

Wang, Y.L. (1985). Exchange of actin subunits at the leading edge of living fibroblasts Possible role of treadmilling. J. Cell Biol. 101.597-602. 

Bessman, S.P. Fonyo, A. (1966). The possible role of mitochondrial bound creatine kinase in regulation of mitochondrial respiration. Biochem. Biophys. Res. Commun. 22, 597-602. 

While activation of HSFl and HSF2 results in the increased expression of HS genes, recent studies indicate that there are distinct differences between these transcription factors. As noted previously, HSFl is the heat-inducible form of the HS factors, whereas HSF2 is activated by hemin (Sistonen et al., 1992). This observation has indicated a possible role of HSF2 in cellular differentiation. It also indicates that the activation domains of the two transcription factors are quite different. Presumably the DNA binding properties of the two transcription factors are similar, but recent experiments indicate otherwise (Kroger and Morimoto,... 

Li, G. Laszio, A. (1985). Thermotolerance in mammalian cells A possible role for the heat shock proteins. In Changes in Eukaryotic Gene Expression in Response to Environmental Stress (Atkinson, B.G. Walden, D.B. eds.), pp. 349-371, Academic Press, Orlando. 

Jonge, V. N. de and Villerius, L. A. (1989). Possible role of carbonate dissolution in estuarine phosphate dynamics. Limnol. Oceanogr. 34, 332-340. 

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