Superoxide dismutase manganese

CL Eisher, J-L Chen, J Li, D Bashford, L Noodleman. Density-functional and electrostatic calculations for a model of a manganese superoxide dismutase active site in aqueous solution. J Phys Chem 100 13498-13505, 1996. 

Maragos, W.F., Jakel, R., Chesnut, D. et al. Methamphetamine toxicity is attenuated in mice that overexpress human manganese superoxide dismutase. Brain Res. 878 218, 2000. 

W.C. Stallings, C. Bull, J.A. Fee, M.S. Lah, and M.L. Ludwig, Iron and manganese superoxide dismutases catalytic inferences from the structures. Current Communications in Cell Molecular Biology. 5, 193-211 (1992). 

K.M. Beem, J.S. Richardson, and D.C. Richardson, Manganese, superoxide dismutases from Escherichia coli and from yeast mitochondria preliminary x-ray crystallographic studies. J. Mol. Biol. 105, 327-332 (1976). 

F. Yamakura, K. Kobayashi, H. Ue, and M. Konno, The pH-dependent changes of the enzymic activity and spectroscopic properties of iron-substituted manganese superoxide dismutase. A study on the metal-specific activity of Mn-containing superoxide dismutase. Eur. J. Biochem. 227, 700—706 (1995). 

Schmiedt, W., Kovacs, G., Pill, J., Metz, J., and Deigner, H.P., 1998, Apoptosis caused by oxidized LDL is manganese superoxide dismutase and p53 dependent, FASEB J. 12 461-467. 

Schmid-Grendelmeier P, Fluckiger S, Disch R, Trautmann A, Wuthrich B, Blaser K, Scheynius A, Crameri R IgE-mediated and T cell-mediated autoimmunity against manganese superoxide dismutase in atopic dermatitis. J Allergy Clin Immunol 2005 115 1068-1075. 

Time-course of human manganese superoxide dismutase reaction after generation of superoxide by pulse radiolysisT The experiment demonstrates decrease in absorbance at 250 nm (e = 2000 M cm ) for a solution containing 0.5/aM enzyme, 50/aM EDTA, 10 mM sodium formate, and 2 mM sodium pyrophosphate at pH 9.4 and 20°C. The starting concentrations of superoxide were 11.6 /xhA (upper curve), 6.5 /aM (middle curve), and 3.4 /aM (lower curve). The calculated progress curves shown as solid lines were obtained by using the KINSIM software and the model of Bull et aF Reproduced here with the permission of the authors and the American Chemical Society. 

Das KC, Guo X, White CW (1998) Protein kinase C8-dependent induction of Manganese superoxide dismutase gene e q>ression by microtubule-active anticancer drugs. J Biol Chem 273 34639-34645... 

Fig. 16 Catalytic cycle of manganese superoxide dismutase X is a dead-end peroxide complex (Reprinted with permission from Ref 103, Copyright 2000, Marcel Dekker).

I 76 Electrochemistry of the Group 7 Elements Manganese, Technetium, and Rhenium Tab. 6 Redox potentials of manganese superoxide dismutase... 

Kim H. C Jhoo W. K Kim W. K Suh J. H Shin E. J., Kato K and Ho K. K. (2000b). Animmuno-cytochemical study of mitochondrial manganese-superoxide dismutase in the rat hippocampus after kainate administration. Neurosci. Lett. 281 65-68. 

Hohmeier, H.E., Thigpen, A., Tran, V. V., Davis, R. andNewgard, C.B. (1998) Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1 beta-induced cytotoxicity and reduces nitric oxide production. J. Clin. Invest., 101, 1811-1820. 

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