Spanish sage

Tildesley NTJ, Kennedy DO, Perry EK, Ballard CG, Savalev S, Wesnes KA, Hylands P and Scholey AB (2003). Salvia lavandulaefolia (Spanish sage) enhances on memory in healthy young volunteers. Pharmacology, Biochemistry and Behavior, 75, 669-674. 

Tildesley N. (2003) Salvia lavandulaefolia (Spanish sage) enhances memory in healthy young volunteers. Pharmacol Biochem Behav 75 669-674. 

Spanish sage oil is produced by steam distillation of leaves and twigs of Salvia lavandulifolia Vahl growing in Spain in the provinces Granada, Murcia, Almaria, and Jaen. The oil is an almost colorless to pale yellow liquid with the characteristic camphoraceous odor of the leaves. 

Unlike Dalmatian sage oil, Spanish sage oil does not contain a- or /3-thujone camphor and 1,8-cineole are the major components [760-762a] and are responsible for the odor of the oil, which is used primarily in pharmaceutical preparations and in technical perfumery. FCT 1976 (14) p.857 [8022-56-8], [95371-15-6]. 

Potential activities for the treatment of Alzheimer s disease were demonstrated in a pilot open-label study involving oral administration of the EO of Salvia lavandulaefolia Vahl. known as Spanish sage [390]. 

Esters are generally safe to use, with low toxicity (see exception of methyl salicylate and sabinyl acetate found in Spanish sage). Although few essential oils have esters as their main components, esters are found in greater numbers than other functional groups. 

Additional remark Under the name Spanish sage oil , an essential oil of S. lavandu-lifolia Vahl [290-272-9 90106-49-3] is commercially available. As specified in ISO [272], it contains 1,8-cineole (10-30%), camphor (11-36%) and linalool/linalylacetate in higher amounts than the Dalmatian oil , various monoterpenes hydrocarbons, bomeol, -terpinylacetate and sabinylacetate. 

Salvia hispanica L. SCN chia OCN Spanish sage Part seed... 

Spanish sage oil Light, yellowish oil with a fresh, camphor-like odor resembling Eucalyptus. Production By steam distillation from the herbage of the Spanish sage. Salvia lavandulifolia. 

Synonyms Sage oil, Spanish Salvia lavandulaefolia Salvia lavandulaefolia oil Spanish sage oil... 

Tildesley, N. T. J., Kennedy, D. 0., Perry, E. K Ballard, C. G Savelev, S Wesnes, K. A., Scholey, A. B. 2003. Salvia lavandulaefolia (Spanish sage) enhances memory in healthy young volunteers. Pharmacol. Biochem. Behav. 75(3) 669-674. 

Neroli oil (formerly bitter-orange ower oil) Nutmeg oil Peppermint oil Pine silvestris oil Rosemary oil Spanish sage oil Spike lavender oil Star anise oil Sweet orange oil... 

This oil is produced from C. camphora Sieb. wood in China and Taiwan. Many chemotypes and also varieties from Cinnamomum species exist, but the true camphor oil is meant. This oil is rarely adulterated because of the cheap price but, fractioned and enriched in camphor up to 90%, is used to mix up camphor containing oils like rosemary, Spanish sage, and spike lavender. Smallest traces of safrole (a carcinogenic compound) shows the use of C. camphora higher boiling fractions. 

Spanish sage oil Salviae lavandulifoliae aetheroleum Salvia lavandulifolia Vahl. 

Source Sage Salvia officinalis L. Spanish sage Salvia lavandulaefolia Vahl (Family Labiatae or Lamiaceae). 

Salvia lavandulaefolia is closely related to S. officinalis. It grows wild in Spain and southwestern France. Spanish sage oil is obtained by steam distillation of its leaves. 

Phenolic acids (e.g., salvin and salvin monomethyl ether) isolated from sage have antimicrobial activities, especially against Staphylococcus aureus.Antileishmanial activity has recently been reported for sage polyphenolics, which also exhibited immunomodulatory activity. Spanish sage oil has also been reported to have antimicrobial... 

Sage leaf extracts and Spanish sage oil were found to enhance memory and to be beneficial in the management of Alzheimer s disease through interaction with the cholinergic system and protection against beta-amyloid protein neurotoxicity, respectively3 ... 

Other recently reported activities for sage include anti-inflammatory, antidia-betic, antitumor in addition to benzodiazepine receptor binding, reduced lipid absorption (camosic acid), and activation of peroxisome proliferator-activated receptor gamma. Infusions and suspensions of Spanish sage have hypoglycemic activity in... 

Spanish sage oil was nonirritating and nonsensitizing to human skin and skin of laboratory animals it was also nonphototoxic on mice and swine. 

Sage, sage oleoresin, and Dalmation sage oil Spanish sage oil. Sage was formerly official in... 

Regulatory Status. GRAS (sage, 182.10 and 182.20 Spanish sage, 182.20) no thujone limit for sage oil is specified (see absinthium). Subject of a positive German therapeutic monograph allowed for internal use in dyspeptic complaints, and as diaphoretic internally for inflamed oral mucous membranes. ... 

It is soluble in 2 volumes of 80 per cent alcohol. Spanish sage oil has the following characters... 

An example of the medicinal plant is Rosmarinus officinalis which has chemical components that has significant antioxidant activity [3-6]. Carvalho, Jr. et al., [6] obtained Rosmarinus officinalis extracts via supercritical extraction with CO2 (CO2-SFE) with high antioxidant activity and identified camphor, 1,8-cineole, camosic acid and rosmarinic acid, moreover studied changes in the production scale of extracts. Vincent et al., [7] isolated, by supercritical fluid chromatography, camosic acid (over 80% by mass) from extracts obtained via SFE Rosmarinus officinalis. Camphor, 1,8-cineole, camphene, bomeol, myrcene and a-pinene can be identified as major compounds in extracts via CO2-SFE Spanish sage [8]. 

E. Langa, G. Della Porta, A.M.F. Palavra, J.S. Urieta, A.M. Mainar, Supercritical fluid extraction of Spanish sage essential oil Optimization of the process parameters and modelling. The Journal of Supercritical Fluids 49 (2009), p. 174-181. 

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