Amyloid beta proteins

Inouye H, Fraser PE, Kirschner DA. Structure of beta-crystalline assemblies formed by Alzheimer beta-amyloid protein analogues analysis by X-ray diffraction. Biophys J 1993 64 502-519. 

Kawahara, M., and Kuroda, Y. (1997). [Molecular mechanism of neuronal death in Alzheimer s disease Ca(2+)-channel formation of beta amyloid protein molecules]. Tanpakushitsu Kakusan Koso 42, 2002-2010. 

Nabeshima, T., and Nitta, A. (1994). Memory impairment and neuronal dysfunction induced by beta-amyloid protein in rats. Tohoku J Exp Med 174, 241—249. 

Heinonen O, Soininen H, Syrjanen S, et al. beta-Amyloid protein immunoreactivity in skin is not a reliable marker of Alzheimer s disease. An autopsy-controlled study. Arch Neurol 1994 51(8)799-804. 

Palmert MR, Usiak M, Mayeux R, Raskind M, Tourtellotte WW, Younkin SG. Soluble derivatives of the beta amyloid protein precursor in cerebrospinal fluid Alterations in normal aging and in Alzheimer s disease. Neurology 1990 40(7) 1028-1034. 

Sisodia, S.S., Koo, E.H., Beyreuther, K., Unterbeck, A. and Price, D.L. (1990) Evidence that beta-amyloid protein in Alzheimer s disease is not derived by normal processing. Science 248,492 195. 

Jarrett, J.T., Berger, E.P. and Lansbury, Jr. P.T. (1993) The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation implications for the pathogenesis of Alzheimer s disease. Biochemistry 32,4693 1697. 

McGeer EG, McGeer PL (2003) Infleunmatory processes in Alzheimer s disease. Prog Neuropsychopharmacol Biol Psychiatry 27 741-749 Meda L, Cassatella MA, Szendiei Gl, Otvos L Jr., Baron P, Wlalba M, Ferrari D, Rossi F (1995) Activation of microgUtil cells by beta-amyloid protein and interferon-gamma. Nature 374 647-650... 

Pike CJ, Walencewicz AJ, Glabe CG, Cotman CW (1991) In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity. Brain Res 563 311—314 Prasad AS, Miale A Jr., Farid Z, Sandstead HH, Schulert AR (1963) Zinc metabolism in patients with the syndrome of iron deficiency anemia, hepatosplenomegaly, dwaifism, and hypognadism. J Lab Qin Med 61 537-549... 

Zamani MR, AUen YS, Owen GP, Gray JA (1997) Nicotine modulates the neurotoxic effect of beta-amyloid protein(25-35) in hippocampal cultures. Neurorepoit 8 513-517 Zhang J, Liu Q, Chen Q, Liu NQ, Li FL, Lu ZB, Qin C, Zhu H, Huang YY, He W, Zhao BL (2006) Nicotine attenuates beta-amyloid-induced neurotoxidty by regulating metal homeostasis. FASEB 120 1212-1214... 

Fan SA, Banks WA, Uezu K, Sano A, Gaskin FS, Morley JE (2003) An dbody to beta-amyloid protein increases acetylcholine in the hippocampus of 12 month SAMP8 male mice. Life Sci 73 555—562. 

Lindberg C, Selenica ML, Westlind-Dauielsson A, Schultzberg M (2005) Beta-amyloid protein structure determines die nature of cytokine release horn rat microglia. J Mol Neurosci 27 1—12. 

Sandliu FA, Salim M, Zain SB (1991a) Expression of die human beta-amyloid protein of Alzheimer s disease specifically in die brains of ti ansgenic mice. J Biol Chem 266 21331—21334. 

A randomized, controlled trial evaluating the efficacy of simvastatin on disease progression in patients with AD provided conflicting results. Overall, the plasma levels of beta amyloid protein remained relatively unchanged after 6 months of treatment, but those with better cognitive function demonstrated a greater reduction in beta amyloid protein levels than patients with more severe dementia (Simons et al.,... 

Qiu L, Buie C, Reay A, Vaughn MW, Cheng KH (2011) Molecular dynamics simulations reveal the protective role of cholesterol in beta amyloid protein-induced membrane disruptions in neuronal membrane mimics. J Phys Chem B 115 9795-9812... 

Cui S, Sim Y, Liu C (2012) Effect of bush-enyisui formula on brain tissue apoptosis and Bcl-2 in beta-amyloid protein-induced Alzheimer s disease rat models. J Tradit Chin Med 32 646-650... 

ADAS-COG Alzheimer s Disease Assessment Scale—Cognition ADRDA Alzheimer s Disease and Related Disorders Association apo E apolipoprotein E APP amyloid precursor protein /SAP beta-amyloid protein CYP450 cytochrome P450 enzyme system DSM-IV-TR Diagnostic and Statistical Manual of Mental Disorders, 4th ed.. Text Revision FAQ functional activities questionnaire MMSE mini-mental status exam NFT neurofibrillary tangle... 

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