Small-pox

Bauer DJ, Stvincent L, Kempe CH, Downie AW (1963) Prophylactic treatment of small pox contacts with V-methylisatin beta-thiosemicarbazone (Compound 33t57, Marboran). Lancet 35 494 96... 

A wide variety of organotin compounds developed by Carraher, Sabir, Roner, and others based on known antiviral drugs such as acyclovir and known antibacterial agents such as ciprofloxacin, norfloxacin, cephalexin (structure 11.21), and ampicillin inhibit a wide variety of viruses including ones responsible for many of the common colds, chicken pox, small pox, shingles, and herpes simplex. 

Coleman, B. Some Observations on the New Method Of Receiving the Small Pox by Ingrafting or Inoculating. Harvard College 1721 [cited December 10, 2004]. http //www.ncbi.nlm.nih.gov/books/ bookres.fcgi/history/pdf colman.pdf. 

Viruses have no cell wall and made up of nucleic acid core enclosed in a protein coat which consists of identical subunits. Viruses are of two types, DNA (deoxyribonucleic acid) viruses and RNA (ribonucleic acid) viruses. DNA viruses are herpes simplex, small pox, hepatitis B, varicellazoster etc. and RNA viruses are rabies, measles, dengue, rubella, yellow fever, poliomyelitis and HIV etc. 

The result of vaccination programmes have been very impressive. The treatment of certain infectious diseases have been drastically reduced, with their virtual elimination from some countries where they formerly caused considerable disability and many deaths. Vaccination has also opened up the possibility of completely eradicating some diseases from the face of the earth e.g. small pox and polio. 

Arguing that the final goal was the eradication of small pox, a scheme was devised whereby each visitor was rewarded according to the absence of smallpox in their area. However, although the visitors consistently earned good bonuses, smallpox remained endemic. When considered from the visitors perspective the reasons for this apparently paradoxical situation becomes clear. If you are rewarded for the lack of cases, the incentive is to turn a blind eye. When in doubt don t report. The system is obviously open to abuse. 

The following section describes various aspects involved in planning and conducting mass immunization and prophylactic treatment for your local area clinics. Factors such as state and local planning, estimating vaccine and medication needs, clinic site selection, staffing patterns, and detailed description of supplies and equipment needs are discussed. Principles for this section have been drawn from the Small Pox Vaccination Clinic... 

By March 1864 health was still an ever-present concern, but only then could Waller see the Union Navy that stood between him and much-needed supplies. Camped near Smithfield, North Carolina, he wrote to his sister, I fear if we stay here long we will have plenty of sickness. There is small pox here now in the fall they have yellow fever and cholera. i9 But he added ominously, I could see the billows on the ocean rising like mountains looking as white as cotton away in the distance the masts of ships were visable [sic], supposed to be the [Union] blockading fleet. 20... 

Biological products have a longer history than is generally assumed. At one time small pox accounted for 10% of deaths in some countries. The development of cow pox vaccination in 1796, and later the Variocella vaccine, has led to small pox being the only infectious disease ever to have been eradicated from the planet the final outbreak was after a laboratory accident in 1979, leading to a small number of cases. 

K3. Kempe, C. H., Studies on smallpox and complications of small-pox vaccination. Pediatrics 26, 176-189 (1960). 

R. usambarense Leaves used for coughs or ground and mixed with water to stop stomach-ache. Whole plant is used for treatment of small pox. 

Agent Index A318 Class Index C27 Monkey Pox Type Virus Clinical symptoms closely resemble small pox and include extreme fatigue, fever, muscular and back pain, with evolution of maculas progressing successively to papules, vesicles, pustules, and scabs. Routes Inhalation Abraded Skin Mucous Membranes Secondary Hazards Aerosol Contact Body Fluids Fomites Incubation 7 to 15 days Mortality Rate < 15% Reservoir Monkeys, Squirrels Direct Person-to-Person Transmission is possible. 

Istanbul. He described the outcome in a small book entitled Account of Inoculating the Small Pox published in 1723 ... 

Synthetic biology uses the DNA sequence information of a virus to resynthesize the viral molecule via throughput technology of nucleotide synthesis and robotics. Using these technologies, it is possible, for example, to spread the small pox virus, and cause mass chaos which has been already eliminated from the earth. Thus, the power of synthetic biology has to be protected from terrorists just like the nuclear bombs falling in their hands. 

Small-Pox. to prevent Pitting in 5759 Sraoll-Pox. to remove Pitting after. 57C2... 

K. In manufacturing other products, to prohibit to use the equipment and utensils of the room dealing with small pox viruses, acute poliomyelitis viruses, spore-forming pathogens or Mycobacterium tuberculosis, with the labels attached to them for each type of product. 

There is a great opportunity for a major triumph in global public health with the global elimrnation of brain damage due to iodine deficiency disorders, comparable to the elimination of small pox and polio. 

Camel poxvirus—a pathogen that can attack humans, but not those who live next to camels and so are naturally immune. The Iraqis have also used this virus as a model to the small pox virus. 

Class Index C27 resemble small pox and Inhalation days... 

Hanna W. Studies in small pox and vaccination. Bristol, England Wright 1913. 

Vaccines are the most effective means of prevention of diseases. Eradication of small pox worldwide attests to the power of this preventive strategy. The rarity of infectious diseases such as diphtheria, tetanus, pertussis, mtunps, and measles in the Western world is largely due to success-fill immunizations. Development of effective vaccines is seen as the hope for prevention of other infectious diseases such as malaria, AIDS, and hepatitis B and C infections. 

John Gough, who at the age of three lost his sight after an attack of small pox, was bom in the English li e District in 1757. He was tiie son of a shearer-dyer who helped John to overcome his disability by teaching him to develop his touch and tongue in order to visualize his surroundings. He was also encouraged to conduct experiments in his father s dye house. 

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