HIV prevention strategies

HIV-1 integrase strand transfer inhibitors, 45, 263 HIV prevention strategies, 40, 277 HIV protease inhibitors, 26,141 29, 123 HIV reverse transcriptase inhibitors, 29,123 HIV therapeutics, 40, 291 HIV vaccine, 27, 255... 

Stringer JS, Sinkala M, Rouse DJ, Goldenberg RL, Vermund SH. Effect of nevirapine toxicity on choice of perinatal HIV prevention strategies. Am J Public Health 2002 92(3) 365-6. 

Estimates of the lifetime COl are needed for temporal and international comparisons and for assessment of the efficiency of prevention strategies. During the first years of HIV/AIDS treatment, direct lifetime costs were only estimated by simple projections based on retrospective data. Later, specific statistical tools were adopted to estimate life expectancy and lifetime costs. The results of lifetime estimates are very sensitive to imputed assumptions. Table 4 demonstrates some studies in this field. 

Early detection of HIV infection is vital in controlling its spread however, individuals in resource-limited settings feel they have no reason to find ouf about their HIV status if there are no treatment interventions. The availability of freafmenf will acf as an incentive for these individuals to seek testing and counseling. There is also a strong need to create and sustain a medical and public health infrastructure in the developing world and also scale up proven prevention strategies. 

Despite developments in the field of molecular biology, virology, immunology, and pharmacology, fhe confrol of HIV-1 still awaits effective vaccines and microbicides. Because significant technological advances are still required to overcome the unique obstacles posed by HIV-1, we must find ways to scale up proven prevention strategies and also provide access to HIV treatment for the infected individuals in the world. 

Studies of coreceptors have suggested novel avenues for developing therapeutic and preventive strategies against HIV and acquired immunodeficiency syndrome... 

Studies of co-receptors have suggested novel avenues for developing therapeutic and preventive strategies against HIV and acquired immunodeficiency syndrome (AIDS). These strategies build on an understanding of the role of chemokine receptors in HIV-1 transmission and pathogenesis [317-320],... 

Seth RB, Sun L, Chen ZJ (2006) Antiviral innate immunity pathways. Cell research 16 141-147 Shapiro RL, Thior I, Gilbert PB, Lockman S, Wester C, Smeaton LM, Stevens L, Heymann SJ, Ndung u T, Gaseitsiwe S et al. (2006) Maternal single-dose nevirapine versus placebo as part of an antiretroviral strategy to prevent mother-to-chUd HIV transmission in Botswana. Aids 20 1281-1288... 

There is a great need to advance novel strategies for anti-HIV therapeutics. Small organic molecules that target unique viral RNA sites and that can prevent the... 

The treatment of patients with AIDS and individuals infected by HIV is continually being modified as new drugs become available and more information is gained about the nature of the AIDS virus. Currently, the pharmacologic management of HIV-infected patients consists of two principal strategies (1) controlling the proliferation and effects of HIV in individuals infected with this virus and (2) treatment and prevention of various opportunistic infections that... 

Even the two-inoculation strategy still would not prevent a patient from being infected. What Merck was aiming for was what is known as a partial protection vaccine that keeps the virus in check once it s inside the body. This is somewhat controversial there s the risk that people, thinking that vaccination means they re immune, will let down their guard and have unsafe sex. It s also not clear whether a vaccine could work against more than one strain of HIV if a person... 

Nevirapine is a non-nucleoside reverse transcriptase inhibitor (1). Concerns about the adverse effects of nevirapine have delayed its implementation in preventing perinatal HIV. Decision analysis has been used to compare three strategies a single dose of nevirapine, a short course of zidovudine, and no intervention (2). The... 

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