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Serum potassium concentration

Mild (5.S-6.5 mEq/L) to moderate (6.5-8 mEq/L) potassium blood level increases may be asymptomatic and manifested only by increased serum potassium concentrations and characteristic BOS changes such asdisappearance of P waves or Rereading (widening) of the QRS complex. [Pg.644]

Serum potassium concentration Is Increased by the concurrent administration of Intravenous potassium penicillin 6. The penicillin preparation contains 1.7 mmol of potassium per million units. Thus, a patient receiving 10 million units of the antibiotic receives 17 mmol (m q.) of potassium. [Pg.274]

Aldosterone antagonists Hypotension, hyperkalemia, increased serum creatinine BP and HR every shift during oral administration during hospitalization, then once every 6 months baseline SCr and serum potassium concentration SCr and potassium at 48 hours, at 7 days, then monthly for 3 months, then every 3 months thereafter following hospital discharge... [Pg.103]

Assess possible correctable etiologies, including myocardial ischemia, serum potassium concentration (for hyperkalemia), and thyroid function tests (for hypothyroidism). [Pg.113]

Monitor serum potassium in patients receiving high-dose or continuous nebulization of a short-acting p2-agonist. Serum potassium concentrations should be obtained upon admission, and if hypokalemic, every 4 hours (after each 30 to 40 mEq or mmol of replacement) until the patient s potassium is stable. Potassium should be monitored every 3 to 6 months after discharge. [Pg.229]

As nephron mass decreases, both the distal tubular secretion and GI excretion are increased because of aldosterone stimulation. Functioning nephrons increase FEK up to 100% and GI excretion increases as much as 30% to 70% in CKD,30 as a result of aldosterone secretion in response to increased potassium levels.30 This maintains serum potassium concentrations within the normal range through stages 1 to 4 CKD. Hyperkalemia begins to develop when GFR falls below 20% of normal, when nephron mass and renal potassium secretion is so low that the capacity of the GI tract to excrete potassium has been exceeded.30... [Pg.381]

The body s normal daily potassium requirement is 0.5 to 1 mEq/kg (0.5 to 1 mmol/kg) or 40 to 80 mEq (40 to 80 mmol) to maintain a serum potassium concentration of 3.5 to 5 mEq/L (3.5 to 5 mmol/L). Potassium is the most abundant cation in the ICF, balancing the sodium contained in the ECF and maintaining electroneutrality of bodily fluids. Because the majority of potassium is intracellular, serum potassium concentration is not a good measure of total body potassium however, clinical manifestations of potassium disorders correlate well with serum potassium. The acid-base balance of the body affects serum potassium concentrations. Hyperkalemia is routinely seen in... [Pg.410]

Hyperkalemia is defined as a serum potassium concentration greater than 5 mEq/L (5 mmol/L). Manifestations of hyperkalemia include muscle weakness, paresthesias, hypotension, ECG changes (e.g., peaked T waves, shortened QT intervals, and wide QRS complexes), cardiac arrhythmias, and a decreased pH. Causes of hyperkalemia fall into three broad categories (1) increased potassium intake (2) decreased potassium excretion and (3) potassium release from the intracellular space. [Pg.412]

ACE inhibitors decrease aldosterone and can increase serum potassium concentrations. Hyperkalemia occurs primarily in patients with chronic kidney disease or diabetes and in those also taking ARBs, NSAIDs, potassium supplements, or potassium-sparing diuretics. [Pg.132]

Serum potassium concentration is usually maintained in the normal range until the GFR is less than 20 mL/min per 1.73 m2, when mild hyperkalemia is likely to develop. [Pg.878]

Treatment of hyperkalemia depends on the desired rapidity and degree of lowering (Fig. 78-4, Table 78-6). Dialysis is the most rapid way to lower serum potassium concentration. [Pg.906]

Calcium administration rapidly reverses ECG manifestations and arrhythmias, but it does not lower serum potassium concentrations. Calcium is short acting and therefore must be repeated if signs or symptoms recur. [Pg.906]

Renal function impairment Renal function impairment requires careful monitoring of the serum potassium concentration and appropriate dosage adjustment. [Pg.33]

Parenteral /32-agonists such as albuterol (salbuta-mol) increase the activity of the membrane sodium-potassium ATPase, and so increase potassium entry into cells. Nebulized or infused albuterol (salbutamol) significantly lowers serum potassium concentration over 5 hours. A suitable initial dose of nebulized albuterol is 5 mg in adults. It can provoke tremor and tachyarrhythmia, and it is desirable to monitor cardiac rhythm during nebulization. The combination of nebulized albuterol (salbutamol) with infusion of insulin + glucose is more effective than the infusion alone. [Pg.510]

The serum potassium concentration can be effectively reduced by dialysis, and this is often indicated in patients presenting with renal failure and acute hy-perkaleamia. However, dialysis may take some time to institute, especially if the patient has to be transferred to a specialist centre. Calcium polystyrene sulphonate is often used, but there is little evidence of efficacy and its use is not entirely without risk. [Pg.510]

Additive effects with other agents increasing serum potassium concentration. May alter renal excretion of substances other than potassium (eg, digoxin, hydrogen ions). [Pg.1399]

Hypokalemia occurred in 29 children undergoing insulin tolerance tests the mean serum potassium concentration at the start was 4.1 mmol/1, falling to a mean of 3 mmol/1 at 30 minutes (108). Ten children had a serum potassium concentration below 2.9 mmol/1 and one had a concentration of 2.2 mmol/1. There were no cardiac events. [Pg.399]

The serum potassium concentration was 2.6 mmol/1. Catecholaminergic polymorphous ventricular tachycardia was later diagnosed. [Pg.399]

In another open study of elderly men and women, one of 30 subjects developed generalized weakness in association with a serum sodium concentration of 125 mmol/1 and a serum potassium concentration of 3.1 mmol/1 (52). [Pg.482]

Because indomethacin may increase serum potassium concentrations, indomethacin and spironolactone should be administered concomitantly with caution. Potassium-sparing diuretics should be used with caution, and serum potassium should be determined frequently in patients receiving an angiotensin-converting enzyme (ACE) inhibitor (e.g., captopril). Concomitant administration with an ACE inhibitor may increase the risk of hyperkalemia. The dosage of spironolactone should be reduced, or the drug discontinued, as necessary. Patients with renal impairment may be at increased risk of hyperkalemia [65]. [Pg.311]

A 25-year-old man, who had taken lithium for 5 years, awakened from sleep unable to move his limbs and had a generalized flaccid paralysis with a serum potassium concentration of 2.1 mmol/1 (330). Lithium was withdrawn and he responded to treatment with intravenous potassium chloride. [Pg.143]

The authors of this report thought that the Brugada syndrome was probably not due to chlorpromazine or lithium in this patient, and it has not been previously described with heroin. It may have been due to hyperkalemia (as the Brugada pattern normalized when the serum potassium concentration normalized), perhaps facilitated by cocaine. Another case of Brugada syndrome is described under Drug overdose . [Pg.495]

A healthy 31-year-old man developed acute renal insufficiency 18 hours after inhaling cocaine 5 g. His blood pressure was 150/100 mmHg, his serum creatinine 177 pmol/l, creatine phosphokinase activity 107 U/l, and serum potassium concentration 3.8 mmol/1. The urinary sodium concentration was 30 mmol/1 and there was a trace of protein and 1-2 red blood cells per high-power field. Immunological studies were unremarkable. Ultrasound showed kidneys of normal size with hyperechogenity of the right kidney. Over the next 10 days he recovered spontaneously. [Pg.508]

AMIODARONE POTASSIUM-SPARING DIURETICS Risk of T levels of eplerenone with amiodarone risk of hyperkalaemia directly related to serum levels Calcium channel blockers inhibit CYP3A4-mediated metabolism of eplerenone Restrict dose of eplerenone to 25mg/day. Monitor serum potassium concentrations closely watch for hyperkalaemia... [Pg.13]

Potassium depletion. Diuretics, which act at sites 1, 2 and 3 (Fig. 26.1), cause more sodium to reach the sodium-potassium exchange site in the distal tubule (site 4) and so increase potassium excretion. This subject warrants discussion since hypokalaemia may cause cardiac arrhythmia in patients at risk (for instance patients receiving digoxin). The safe lower limit for serum potassium concentration in such patients is normally quoted as 3.5mmol/l. Whether or not diuretic therapy causes significant lowering of serum potassium depends both on the drug and on the circumstances in which it is used. [Pg.536]

Amiloride is a therapeutic option in reducing potassium losses in patients receiving amphotericin. When it was given to 19 oncology patients with marked amphotericin-induced potassium depletion mean serum potassium concentrations increased in the 5 days before and after administration (from 3.4 to 3.9 mmol/1) (8). There was also a trend toward reduced potassium supplementation (48 versus 29 mmol/day). Adverse reactions were limited to hyperkalemia in two patients who took amiloride 20 mg/day and a high potassium intake. [Pg.113]

A 72-year-old man was treated with ceftriaxone (2 g bd) and gentamicin (80 mg tds) for a severe urinary tract infection (75). On day 5 his serum potassium concentration was 3 mmol/1 with a normal serum creatinine and urine examination. Despite treatment with oral potassium chloride plus a high potassium diet, his serum potassium fell to 2.3 mmol/1 4 days later, accompanied by inappropriate kaliuresis, hypouricemia with inappropriate uri-cosuria, and hypophosphatemia with inappropriate phosphaturia. There was no bicarbonate wasting, but there was proteinuria 1.2 g/day, with a predominance of low molecular weight proteins in contrast, serum creatinine was normal and creatinine clearance was 78 ml/minute. The aminoglycoside was withdrawn with subsequent progressive improvement in renal proximal tubular function, which normalized 9 days later. [Pg.123]


See other pages where Serum potassium concentration is mentioned: [Pg.102]    [Pg.333]    [Pg.411]    [Pg.412]    [Pg.1476]    [Pg.509]    [Pg.610]    [Pg.274]    [Pg.647]    [Pg.320]    [Pg.263]    [Pg.311]    [Pg.495]    [Pg.504]    [Pg.506]    [Pg.893]   
See also in sourсe #XX -- [ Pg.18 ]




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Serum concentration

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