Schedules target chemicals

There are challenges in the CWC-related analysis. Even though the schedules restrict the number of possible target chemicals, the theoretical number of chemicals is still over ten thousand, even hundreds of thousands. Naturally, the number of practically important chemicals is much smaller. The properties of the chemicals vary from solids to gases and from volatile to nonvolatile chemicals. In IR, the absorptivities vary considerably. 

This Accelrys provided database is based on the journals of the Royal Society of Chemistry (RSC) (308). It primarily contains information on the metabolic fate of chemicals (including pharmaceuticals, agrochemicals, food additives, and environmental and industrial chemicals) in vertebrates, invertebrates, and plants. New entries can be added, and the database may be searched graphically. This database can be combined with various computational tools from Accelrys for target-specific analysis and modeling. Metabolic pathways are organized alphanumerically, and future releases are scheduled to include a comprehensive survey of the metabolism literature (308,309). 

If a system was returned from inspection, external exercise, or maintenance at the manufacturer, an additional test for cleanness (entrance control) is performed. Three different blank injections with solvent, BSTFA, and DMT are performed and evaluated using an on-site target library containing all MS spectra from the OCAD. Absence of any identification ensures that the system components are free from scheduled chemicals and their degradation products. The same blank injection tests are performed if a system in waiting status was used internally for injections other than check mixture. The on-site target library used in the test of cleanness is removed from the hard disk before issuing the system for a mission. 

Another measure of schedule-controlled behavior is that provided by the distribution of the times between successive responses or interresponse times (IRTs). These can be generated as a frequency distribution and have been shown to be important targets of chemical exposure. For example, lead exposure appears to affect primarily the very short IRTs on FI schedules. Many different drugs from a variety of different classes have been shown to increase the frequency of long IRTs and to decrease the frequency of... 

The chemical service manpower requirement was greater than the theater had ever experienced. There were not enough service units available in the theater, and repeated pleas to the United States resulted in the scheduling of two chemical service units on redeployment from the European theater and one unit from the United States. But these units could not arrive before the operation was well under way, so Unmacht activated two service companies and a provisional chemical detachment in Hawaii. He also secured the assignment of a quartermaster service company to chemical work pending the arrival of other units in the target area. ... 

RCAs are peripheral chemosensory irritants that target the eyes, airways and/or skin. The 1997 CWC defines them as Any chemical not listed in a Schedule, which can produce rapidly in humans sensory irritation or disabling physical effects which disappear within a short time following termination of exposure . Use for riot control purposes is permitted under the CWC, but not for military harassment, and stocks of RCAs must be declared. Most of the major RCAs [CN, CS and dibenz[/),/]-l,4-oxazepine (CR) Scheme 1.8] are low volatility solids and, unless they are used in solution in a spray, they need to be aerosolised for efficient use, for example using pyrotechnic munitions or dispersed as micronised powders. 

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