Sandoz company

The Sandoz company used the dibromoterephthalic acid method. This acid was made from p-xylcnc by brominating it to form 2,5-dibromo-p-xylene and then oxidising this to 2,5-dibromoterephthalic acid. Reaction of one mole of this acid with two moles of an arylamine in the presence of copper(II) acetate gives 2,5-bis(arylamino)terephthalic acid, which can be ring-closed to a linear quinacridone. Unsymmetrical substitution using two different arylamines is possible. 

Abczynska, M., Kazmirek, Z., Syguda, J., and Terminska, K. (1995) Own experience (1989-1994) in the treatment of adolescent schizophrenic paranoid syndromes with Leponex produced by Sandoz Company. Vsychiatr Pol 29 79-85. 

Sandoz, which had ten years earlier initiated experimental studies of LSD, also began to offer synthetic psilocybin to medical and psychological researchers. Thus it came about that psilocybin, the active ingredient of the Mexican hallucinogenic mushroom, was manufactured in tablet form by the Sandoz Company, which had a branch in New Jersey. They offered to supply the Harvard University professor with as much of the drug as he wanted, free of charge, for research purposes. 

In a series of publications, workers from the Sandoz company have described the synthesis or isolation of ergot alkaloids that contain 1,4-dioxopyrrolol 1,2-alpyrazines such 185 or 186. 

The authors thank Drs, Roderich Walter, and Irving L. Schwartz and the Sandoz Company for gifts of various oxytocin analogues. These studies were supported by Training Grant AM 05551-01 from the National Institutes of Health. 

Fine chemical companies are generally either small and privately held or divisions of larger companies, such as Eastman Fine Chemicals (United States) and Lonza (Switzerland). Examples of large public fife science companies, which market fine chemicals as a subsidiary activity to their production for captive use, are Hoffmann-La Roche, Sandoz, and Boehringer Ingelheim, which produce and market bulk vitamins and liquid crystal intermediates, dyestuff intermediates, and bulk active ingredients, respectively. Table 3 fists some representative companies having an important fine chemical business. 

Dinitrochlorobenzene is used primarily in the manufacture of azo dyes other areas include the manufacture of fungicides, mbber chemicals, and explosives. It is produced by Eastman Kodak Company and Sandoz Chemical Corporation and its bulk fob price is 2.73/kg. 2,4-Dinitrochlorobenzene is more toxic than nitrobenzene. It is an extremely powerful skin irritant and must be handled with great cate. 

The chemical industry manufactures a large number of antioxidants (qv) as well as uv stabilizers and their mixtures with other additives used to facilitate resin processing. These companies include American Cyanamid, BASE, Ciba—Geigy, Eastman Chemical, Elf Atochem, Enichem, General Electric, Hoechst—Celanese, Sandoz, and Uniroyal, among others. The combined market for these products in the United States exceeded 900 million in 1994 and will reach 1 billion in the year 2000. 

The Novartis Foundation is an international scientific and educational charity (UK Registered Charity No. 313574). Known until September 1997 as the Ciba Foundation, it was established in 1947 by the CIBA company of Basle, which merged with Sandoz in 1996, to form Novartis. The Foundation operates independently in London under English trust law. It was formally opened on 22 June 1949. 

W. L. Koch, Eli Lilly and Company, Indianapolis, Indiana H. G. Leemann, Sandoz Limited, Basel, Switzerland P. Lim, SRI International, Menlo Park, California H. B, Long, Eli Lilly and Company, Indianapolis, Indiana J. W. McRae, Burroughs Wellcome Company, Research Triangle Park, North Carolina... 

B. Rudy, Burroughs Wellcome Company, Greenville, North Carolina W. D. Schonleber, Sandoz Limited, Basel, Switzerland... 

MICHAEL LEVIN is President and CEO, Metropolitan Computing Corporation (MCC), East Hanover, New Jersey, specializing in process analytical instrumentation as well as data acquisition and control systems for tablet presses, mixers, roller compactors, and other equipment. Prior to forming MCC in 1985, he was a consultant to pharmaceutical companies such as Merck, Sandoz, and Warner-Lambert. A member of the American Association of Pharmaceutical Scientists, the International Society for Pharmaceutical Engineering, and the Biomedical Engineering Society, Dr. Levin received the Ph.D. degree (1985) in biomathematics from the University of Washington, Seattle. 

Sandoz believed that LSD had great potential as a therapeutic drug. However, its increasing street use and association with the counterculture of the sixties made it fall out of favor with most legitimate researchers as well as drug enforcement agencies in various countries, particularly the United States and Britain. As a result, the company stopped producing LSD in 1968. 

The way to estimate strategic value in the financial sense, in other words the premium paid beyond the enterprise value, is probably the valuation issue which is least amenable to any form of method or systematic analysis. Although previous transactions from external benchmarking or from the company s own experience may give some kind of lead, even if there is true comparability between the benchmark and the valuation subject, differences in market conditions from one day to the next will often have major influences on the price of an asset. The acquisition of Hexal by Novartis Sandoz generic division in 2006 was widely criticized at the time as being too costly, yet immediately thereafter Teva bought Ivax to re-establish their market position... 

Wilinson S. G.B. Patent No. 972,917 April 21, 1961 Assigned to Wellcome Foundation Limited a company incorporated in England, London Stoll A., Renz J. D.R. Patent No. 721,001 May 21, 1942 Assigned to Sandoz A.G. in Basel, Schweiz. 

Thioridazine, U.S.P. was obtained at Sandoz Pharmaceuticals Corporation, East Hanover, NJ. Sodium oleate (Purified Grade) was obtained from Fisher Scientific Company, Springfield, NJ. Polyvinyl alcohol (Type III, Hot Water Soluble, P 1763) was obtained from Sigma Chemical Company, St. Louis, MO. Poly(L-lactide) was prepared by Sandoz Ltd. (Basle, Switzerland) and poly(DL-lactide) by Battelle Columbus Laboratories (Columbus, OH). Other materials were of reagent grade unless otherwise specified. 

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