Staphylococcus aureus tetracycline-resistant

In some cases, catechins can also act in synergistic mode when used in association with currently used antibiotic molecules (Table 2). EGCG exhibited synergy with /3-lactams. Sudano Roccaro et al. [73] found that this compound is able to reverse tetracycline resistance in Staphylococcus epidermidis and S. aureus isolates. This synergistic interaction has been explained by inhibition of tetracycline efflux pump activity in microbial cells resulting in an... 

A senior British government veterinarian stated in 1962 (3)> When penicillin was first used in treating mastitis only 2% of the strains of staphylococci recovered from cases of mastitis were resistant to penicillin. Today the figure is over 70%. Between 1958 and 1961, resistance to penicillin (PEN) increased from 62.0% to 70.6%. Resistance to streptomycin (STR), tetracycline and chloramphenicol also increased (. Antibiotic resistance increased for isolates of both mastitis staphylococci and streptococci in Canada between I960 and 1967 (5). In Belgium (6), Staphylococcus aureus strains isolated from cases of bovine mastitis showed increase in PEN resistance from 38% in 1971 to 78% in 1974> but then no further increase to 1980. The resistance situation was reported to remain stable in the Federal Republic of Germany between 1962 and 1975 (7), as also in Australia between 1974 and 1979 (8 ) and Denmark, at a very low level, for the period 1963 to 1978 (9). 

Sad to say, there are also strains of Staphylococcus aureus which owe their resistance to another factor, possibly a change in cell-wall composition. Such strains, which are becoming increasingly common in hospitals, are also resistant to cephalosporins, erythromycin, the aminoglycosides, and the tetracyclines. For them, the only effective antibiotic is a rather unselective one, vancomycin (p. 565), but the synthetic anti-bacterials, such as nitrofurantoin and trimethoprim are usually effective. 

MRSA Methicillin-Resistant Staphylococcus aureus, ARP Antibiotic Resistance Profile AMC Amoxicillin-Clavulanic acid C-Chloramphenicol F Furazolidone Fc FlOTfenicol Gm Gentamycin N Neomycin NAL Nalidixic acid S Streptomycin Su Sulfonamides TFT Tetracycline TMP Trimetoprim AMP ampieillin PEN penicillin OXA oxacillin MET methicillin AXO ceftriaxone CIP ciprofloxacin LEVO levofloxacin GAT gatifloxacin ERY et34bromycin CLI clindamycin CL Cephalexin... 

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