Multiple-resistant Staphylococcus aureus

MoAb monoclonal antibody mod moderate MRSA methicillin-resistant Staphylococcus aureus MS multiple sclerosis MSS A methicillin-sensitive Staphylococcus aureus MTT monotetrazolium MTX methotrexate (chemotherapy agent)... 

The need for new antibiotics is driven by the recent rise in the incidence of resistance to commonly used antibiotics. The emergence of multiple-drug resistance to community-acquired infections, such as those caused by Streptococcus pneumoniae, is particularly alarming due to the ease of transmission [1-4], Recent reports show that methicillin-resistant Staphylococcus aureus, the common cause of hospital-acquired infections, has also moved into the community [5],... 

St. John s wort has been used topically for wound healing for hundreds of years. Antibacterial properties have been reported as early as 1959, with hyperforin found to be the active component. Using multiple concentrations, it was discovered that no hyperforin dilutions had antimicrobial effects on Gram-negative bacteria or Candida albicans. There was, however, growth inhibition for all of the Gram-positive bacteria tested, some with the lowest dilution concentration of 0.1 pg/mL. Hyperforin was also shown to be effective at inhibiting methacillin-resistant Staphylococcus aureus (25). 

Tenover FC (2007) Rapid detection and identification of bacterial pathogens using novel molecular technologies infection control and beyond. CUn Infect Dis 44 418 23 Tenover FC, Vaughn RR, McDougal LK, Fosheim GE, McGowan JE Jr (2007) Multiple-locus variable-number tandem-repeat assay analysis of methidllin-resistant Staphylococcus aureus strains. J CUn Microbiol 45 2215-2219... 

Staphylococcus aureus (multiple drug-resistant strain B294 [2,5] drug-resistant strain B295 [2]) [2, 5]... 

Vancomycin-modified Fe-Pt MNPs have been reported for selective emichment of vancomycin-resistant enterococci and other Gram-positive bacteria (Staphylococcus aureus and Staphylococcus epidermidis). The selective interaction between MNPs and bacterial cell walls (expressing o-Ala-o-Ala as the terminal peptides) is through multiple hydrogen bonding (Gu et al. 2003). 

Pathogens from the Staphylococcus genus are found in both the hospital and the community, and the most prevalent species, aureus,. causes illnesses that range from minor skin abscesses to severe pneumonia, meningitis, and infections of the heart, bloodstream, bone, and joint. Multiple strains of S. aureus are now antibiotic resistant, including a few strains that are partially resistant to vancomycin (18), the last effective antibiotic against... 

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