Record sample

Rao et al. [140] described a study using a commercial pH sensitive radio-telemetry capsule (RTC) to evaluate small bowel and colonic transit time in athletes with gastrointestinal symptoms. The RTC (type 7006 Remote Control Systems, London, UK) consists of a glass electrode with an integral reference cap and battery. RF transmissions from the capsule are detected by a solid-state receiver worn on the belt of the patient. The recorder samples the pH from the capsule at 6 second intervals for a period of 24 hours. They used pH changes as an indication of the pH capsule s movement. A sharp rise in pH from around pH 2 to pH 6 indicates that the capsule has moved into the duodenum from the stomach. Then the pH progressively rises to a plateau around pH 8, which indicates that the capsule has moved into the terminal ileum. Another commercially available wireless pH sensor (Bravo) from Medtronic Inc. has been used to measure esophageal pH for a period of 48 hours and it will be discussed later. 

Electrokinetic Measurements. Electrophoretic mobilities were measured with a flat-cell apparatus manufactured by Rank Brothers, Cambridge, England. In addition, several mobility values were checked for accuracy with a Zeta Meter, New York. Mobilities were determined with a small volume of the suspension (approximately 25 cc) that had been prepared for the adsorption experiments. The pH of the solution was measured prior to determining the electrophoretic mobilities, which involved measuring the velocities of five to ten particles in each direction. An average value of the mobilities was recorded. Samples containing the flocculated particles were dipped into an ultrasonic bath for approximately one second prior to making the pH and mobility measurements. 

As air is drawn towards the impeller blades, it is subjected to centrifugal acceleration. Viable microorganisms in the sampled air are impacted at high velocity onto the surface of the agar strip. After sampling, the strip containing the nutrient is incubated at 30 to 35°C for days. The colonies can be enumerated by visual examination and the results should be recorded. Sampling time with the RCS should be 2 min (= 80 1 air). 

A1-liter polyethylene bottle was used for the extraction studies. A small amount of butane (approximately 0.2 g) of butane was bled into the bottle. The bottle was capped and a 2-ml sample was withdrawn by inserting a syringe needle through the side. Hie sample was then injected into a gas chromatograph. The timer was started and a chromatogram recorded. Samples were taken for 2 h to ensure that the butane was not affected by the bottle. Figure 4.11 depicts the result. 

Freezer storage of record samples and working samples is good, but could possibly be improved if separate facilities for the Analytical Labs were available. Documentation of storage temperatures is needed. Some provisions should be made. .. to notify the lab when record samples can be discarded. 

Fenvalerate on Beets, was analyzed in 1982 by G. Helfman using the GLC procedure for the parent compound, only. The reported data, calculated data, copies and original chromatograms, analytical methodology, record samples, and field data description were easily found, followed, and determined to be acceptable. 

For PIGE measurements, transverse bone sections are cut with a diamond saw and polished with SiC paper, and then placed directly in front of the external proton beam. It is not necessary to coat the sample surface with a conductive layer as the charges are dissipated in air and helium. Step width of the concentration profiles is determined by precisely recorded sample translation in front of the beam. The above experimental conditions were used for F analysis in archaeological bone materials in the applications described in this chapter. 

Mass change versus quasi-equilibrium p simultaneously recorded. Sample T recorded. 

Procedures. The specimens were tested in an Instron Universal testing machine at 0°, 23°, 50°, and 75°C and at crosshead extension rates of 0.02, 0.2, 2.0, and 10.0 inches/min. Clip-on strain gage extenso-meters were used to record sample strain, and testing was done in an environmental chamber capable of maintaining the selected temperature to within 0.5°C. All samples were soaked at temperature for at least 30 min before testing. 

Preliminary TGA and differential thermal analysis (DTA) curves were obtained on individual oxides and on the mixed transition metal-uranium oxides to ascertain the reaction characteristics of the individual systems. The TGA data were obtained on an Ainsworth BR balance equipped with an AU recorder. Samples of 1 gram each were heated to 1100°G. at 10°G. per minute. DTA information was obtained on a Tempres Research Model DT-4A instrument. Samples weighing approximately 50 mg. were heated at 5°G. per minute to 1250°G. Differential temperatures were measured with a platinum-platinum 10% rhodium thermocouple at a recorder sensitivity of 20 microvolts per inch. 

The good news is that harmonization efforts are under way, and basic GLP principles are similar. Nevertheless, differences do exist. Major differences include the requirements for the specific contents of protocols and final reports and the retention times for records, samples, and specimens. Manufacturers must become familiar with the GLPs that concern their products, learn to which worldwide regulatory agencies their data will be submitted, and know which legislation covers the material being produced and evaluated. 

For each different axial load, measure and record sample compression at the following time intervals after application of the axial load 1, 4, 9, 16, 25, 36, 49, and 60 minutes, every two hours for 6 hours, every day for 10 days, and every week up to a total test time of 90 days. If fracture has not occurred by 90 days, except as noted below, the test may be terminated, and tests at lower axial loads need not be run. 

It may be debatable for how long it is useful and thus necessary to retain records, samples and specimens from studies, or check-lists from Quality Assurance inspections, whose results may long have been superseded by new data or by simple experience from the use of the test item. 

In any case, it has to be stressed that it should be possible for all material for which the GLP Principles require retention, to be retrieved and investigated during the whole period of time which the country, where the test facility is located, stipulates as the minimum time of storage. Every change in the conditions of archiving has therefore to be fully documented. Only in this way will it be possible to trace the fate of documents, records, samples and specimens even after their placement into storage. 

Documentation Fill in the raw data sheet TLC II. Note the numbers of the balance used, TLC plate and reference substances. Record sample(s) weight and the quantity of the solvent. Cross the parameter s field to document the obtained result(s) and note the archive number(s) of the videoprints. Transfer the result(s) to the testing protocol. Operator and checker have to sign the raw data sheet with date and initials. All further sheets are to be paginated and signed on the last page. Finally all TLC raw data sheets are added to the batch documentation. 

The heated zone, within which the reactant is maintained throughout each experiment, must be uniform and controlled at a known temperature, which may be constant or varied according to a specified program. The constant temperature zone may be smaller in a null point instrument than where deflection measurements require some sample movements. Separate sensors are often used for the control of furnace temperature and the measurement of the sample temperature. This avoids the possibility of the heating controls exerting any influence on the recorded sample temperature (10). The furnace, which should be noninductively wound to avoid interference with these sensors, may be regulated in response to outputs from a resistance thermometer or a thermocouple. 

As the run proceeds, the accumulated volume leaving the reactor is recorded. Samples of the reactor liquor are also taken periodically and analyzed for calcium and magnesium by atomic absorption. By maintaining a constant reactor pH, the composition remains fairly constant throughout the run. Based upon the flow rate data and the solution composition, the fraction of the stone dissolved and dissolution rate can then be calculated. 

Are protocols in place to identify and record sampling sites and to record in situ data ... 

Prior to spectral recording, samples were oxidised or reduced, according to the following procedures ... 

For the pre-intervention surveys, spot morning urine samples were collected from the first void on waking in the morning. The date and time were recorded. Samples were stored in the dark at 4°C for a maximum of 4 weeks before assay. For the post-intervention surveys casual spot urine samples were collected. An aliquot was drawn from each sample, frozen and transported to the laboratory. 

USA) 1995. Phase 1 14 days phase 2 5 days paediatric teaching hospital. Phase 1 2 units (ICU and medical surgical unit). Phase 2 3 units (ICU, medical and surgical units) Following medication order written from prescribing through administration. Also review of medical record, pharmacy s clinical interventions and quality control log, and incident reports. Also review of medication administration record Sample 3312 medication orders Error rate 24/100 orders Administration error 0.15% doses administered... 

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