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Recombinant human growth factor

Has be used to assess recombinant human growth factor (rhKFG) ... [Pg.417]

A. Baur, R. Reski, G. Gorr, Enhanced recovery of a secreted recombinant human growth factor by stabilising additives and by coexpression of human serum albumin in the moss Physcomitrella patens. Plant Biotechnol. J., in press. [Pg.928]

The use of recombinant hematopoietic growth factors (i.e., the commercially available forms of the native products) has been evaluated in many disorders affecting all types of blood cells. Recombinant human hematopoietic growth factors are identified as rHu. Not all uses discussed have received regulatory approval in all countries. [Pg.581]

The expression of recombinant proteins in cells in which they do not naturally occur is termed heterologous protein production (Chapter 3). The first biopharmaceutical produced by genetic engineering to gain marketing approval (in 1982) was recombinant human insulin (tradename Humulin ), produced in E. coli. An example of a more recently approved biopharmaceutical that is produced in E. coli is that of Kepivance, a recombinant keratinocyte growth factor used to treat oral mucositis (Chapter 10). Many additional examples are provided in subsequent chapters. [Pg.106]

Examples of the early application of recombinant DNA technology in medicine are the development of recombinant human growth hormone human insulin human interferons, thought to have anticancer activity in addition to antiviral activity interleukins (regulatory proteins from lymphocytes that are believed to be important in the treatment of immunodeficiency diseases and cancer) tumor necrosis factor epidermal and bone marrow progenitor cell growth factors and the production of vaccines (Table 12.1). [Pg.415]

Weaver JU, Monson JP, Noonan K, John WG, Edwards A, Evans KA, Cunningham J. The effect of low dose recombinant human growth hormone replacement on regional fat distribution, insulin sensitivity, and cardiovascular risk factors in hypopituitary adults. J Clin Endocrinol Metab 1995 80(1) 153—9. [Pg.515]

Morishita, R., Nakamura, S., Hayashi, S., Taniyama, Y., Moriguchi, A., Nagano, T., Taiji, M., Noguchi, H., Takeshita, S., Matsumoto, K., Nakamura, T., Higaki, J., and Ogihara, T. 1999. Therapeutic angiogenesis induced by human recombinant hepatocyte growth factor in rabbit hind limb ischemia model as cytokine supplement therapy. Hypertension 33 1379-1384. [Pg.297]

Covalent conjugate of recombinant-derived human growth factor (rh G-CSF and monomethoxypolyethylene glycol)... [Pg.452]

Human recombinant keratinocytes growth factor KGF receptor... [Pg.945]

Samples included rCD4 (3), rCD4-IgG (4), rgpl20 (5), rtPA (Activase ) and rhuMAb HER2 (6) all of which were purified from transfected Chinese hamster ovary (CHO) cells. Human rtPA from transfected 293 (human embryonic kidney) cells was prepared as described (7). Bowes melanoma tPA was obtained from American Diagnostica. Human plasma factor IX was kindly provided by Kenneth J. Smith (8). Recombinant human growth hormone (Protropin ), isolated from transfected E. coli (10), was included as a negative control. [Pg.92]

Sun YN, Lee JH, Almon RR, Jusko WJ. A pharmacokinetic/pharmacod5mamic model for recombinant human growth hormone. Effects on induction of insulin-like growth factor 1 in monkeys. J Pharmacol Exp Ther 1999 89 1523-32. [Pg.500]

AbeUan R, Ventura R, Pichini S, Pascual JA, Pacifici R, Di Carlo S, et al. Evaluation of immunoassays for the measurement of insulin-like growth factor-l and pro-coUagen type III peptide, indirect biomarkers of recombinant human growth hormone misuse in sport. Chn Chem Lab Med 2005 43 75-85. [Pg.2001]

Altar, C.A. and Bakhit, C. (1991) Receptor-mediated transport of human recombinant nerve growth factor from olfactory bulb to forebrain cholinergic nuclei. Brain Res. 541 82-88. [Pg.192]

Fernyhough P, Diemel L T, Hardy J, et al. (1995). Human recombinant nerve growth factor replaces deficient neurotrophic support in the diabetic rat. Euro. J. Neurosci. 7 1107-1110. [Pg.1192]

Sharpe, R. J., Byers, H. R., Scott, C. F., Bauer, S. I., and Maione, T. E. (1990) Growth inhibition of murine melanoma and human colon carcinoma by recombinant human platelet factor 4. J. Natl. Cancer Inst. 82(10), 848-853. [Pg.188]

Recombinant human tumor necrosisb factor alpha from an extract of Escherichia coli Recombinant human growth hormone preparation (rhGH)... [Pg.217]

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See also in sourсe #XX -- [ Pg.40 ]

See also in sourсe #XX -- [ Pg.40 ]



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