Protein fatty acid condensates

More recent publications on sulfosuccinates have confirmed the minimal or close to zero skin and eye irritation caused by these products. In a general screening of product safety evaluation methods the authors [16] rejected the sulfosuccinate from further consideration in the statistical analysis of experimental data (variance analysis) because the product had not shown any irritation in the Duhring-Chamber test. The sulfosuccinate (based on fatty alcohol ethoxy late) was tested in a screening with 14 other surfactants, namely, alkyl sulfates, sulfonates, ether sulfates, and a protein fatty acid condensation product. 

Good confirmation of these figures is given in Ref. 111. In this evaluation, a sulfosuccinate was run both in the Zein test and in the RBC test. With both results the sulfosuccinate is described as the second best compatible surfactant after a high molecular weight protein fatty acid condensate. 

Acylated Proteins and Amino Acids (Protein-Fatty Acid Condensates) [19]... 

In the development of the protein-fatty acid condensates it was possible to combine the renewable resources fatty acids (from vegetable oil) and protein, which can be obtained from both animal waste (leather) as well as from many plants, to construct a surfactant structure with a hydrophobic (fatty acid) and a hydrophilic (protein) part (Fig. 4.12). This was carried out by reacting protein hydrolysate with fatty acid chloride under Schotten-Baumann conditions using water as solvent. Products are obtained that have an excellent skin compatibility and, additionally, a good cleaning effect (particularly on the skin) and, in combination with other surfactants, lead to an increase in performance. For instance, even small additions of the acylated protein hydrolysate improve the skin compatibility. An... 

U.S. 5981450 (2000) Fabry et al. (Henkel) Monoglyceride (ether) sulfate amino acid derivatives (acyl gluamates, vegetable protein hydrolyzates, or vegetable protein fatty acid condensates) Mild detergent mixtures... 

Stabilizer T. [GrOnau] Protein fatty acid condensate stabilize f(v bleaching. 

Tephal Gmnau. [Chem-YBV] Protein fatty acid condensate washing, milling, and wetting agent for textiles. 

Such reactions were also reported for commercial cosmetic products [66], in which hydrolized proteins were reacted with various fatty acid chlorides to yield protein-fatty acid condensates that have detergent properties. 

Fatty acids can also act as the hydrophobic component of a surface-active substance by reaction of the carboxylic group with OH- or NH-containing molecules. One example of this is the class of so-called protein fatty acid condensates, which are soft to the skin and are therefore used in cosmetic products. The fatty acid esters or acid chlorides are converted to amides or esters of amino acids or sulfonic acids containing an OH-group. In this way taurates are formed by the reactions of 2-aminoethane sulfonic acid with fatty acids such as lauric, myristic or stearic acid. 

The ability of exogenous proteins to reduce the skin and eye irritation potential of detergents was highlighted many decades ago in the cosmetic chemistry community. First extensive insights were probably those of Meinecke (4), who reported that addition of a protein hydrolysate or a protein-fatty acid condensate to a solution of a highly irritant surfactant (sodium alkylbenzene sulfonate) caused a remarkable increase in the skin tolerability of the product and postulated a protective effect based on the formation of a protein colloidal layer on the skin, which could prevent or minimize the direct interaction of tenside molecules with skin keratin. The same interpretation has been advanced more recently by other authors (116-118). 

High-molecular-weight protein-fatty acid condensates are reported to be more effective than acylated derivatives of smaller peptide in increasing the skin and eye tolerability of different anionic tenside, as evaluated by the red blood cell test (127) and quatemized derivatives also reported to possess anti-irritant properties when included in anionic-based formulations the mucous membrane compatibility of sodium laureth sulfate, as determined by the Draize test, can be increased about fourfold, by replacing of one-third of the surfactant with a lauryldimonium hydroxypropyl hydrolyzed collagen (128). 

Anionic A-acylated L-amino acids, oligopeptides, and protein hydrolysates can be used in the wool finishing process. An increased bath exhaustion and a more intense coloration of wool were obtained during the dyeing of wool by the addition of A-acyl-L-amino acids or commercially available protein-fatty acid condensates [70],... 

The Lamepon S-Range-Protein Fatty Acid Condensates, Technical Bulletin, Henkel, 1986. 

The use of proteins as raw material for personal and home care products has been known for more than 60 years [58]. Both animal (e.g. leather waste) and plant-based proteins are available as raw materials. Nowadays mostly plant-based proteins (e.g. from wheat, soya bean, rice, peas) are used. Typically the natural proteins are degraded by hydrolysis (either chemically or enzymatically) and the respective protein hydrolysates are obtained. After purification and work-up they are used for skin and hair care formulations. The main claims are protection and care for hair and skin. Subsequent quarternization of the protein hydrolysates leads to products with high substantivity and conditioning effects, whereas acylation of the protein hydrolysates with fatty acids results in protein surfactants, the so-called protein fatty acid condensates. In the latter case, as already described for the sugar-based surfactants, the products are based completely on natural raw materials, namely fatty acids (from vegetable oil) and the protein or protein hydrolysate as the hydrophilic part in the surfactant molecule (Figure 4.6). The... 

Chem. Descrip. Protein fatty acid condensates Ionic Nature Anionic... 

Chem. Descrip. Alkylphenol polyglycol ether sulfate/protein fatty acid condensate Ionic Nature Nonionic/anionic Uses Surfactant for detergents, brush cleaners Armac 18D [Akzo Nobel Surf. Chem. AB]... 

Propylenglycolfettsaureester Prostacyclin Prostacyclin Prostaglandins Prostaglandine Protein-Fatty Acid Condensates Eiweifi-Fettsaure-Kondensate Proteins EiweiBe, Proteine Pullulan Pullulan Putties Kitte Pyrethrum Pyrethrum Pyrethrum Plant Persische bzw. Dalma-tinische Insekte, Pyrethrum... 

Prostacyclin prostacycline Prostaglandins prostaglandines Protein-Fatty Acid Condensates produits condenses de protdines et d acides gras Proteins protdines Pullulan pullulane Putties mastics Pyrethmm pyrethre Pyrethmm Plant pyrethre rose... 

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