Protein hydrolysate fatty acid condensates

Figure 4.6 Structure of protein hydrolysate fatty acid condensates.

In the development of the protein-fatty acid condensates it was possible to combine the renewable resources fatty acids (from vegetable oil) and protein, which can be obtained from both animal waste (leather) as well as from many plants, to construct a surfactant structure with a hydrophobic (fatty acid) and a hydrophilic (protein) part (Fig. 4.12). This was carried out by reacting protein hydrolysate with fatty acid chloride under Schotten-Baumann conditions using water as solvent. Products are obtained that have an excellent skin compatibility and, additionally, a good cleaning effect (particularly on the skin) and, in combination with other surfactants, lead to an increase in performance. For instance, even small additions of the acylated protein hydrolysate improve the skin compatibility. An... 

The ability of exogenous proteins to reduce the skin and eye irritation potential of detergents was highlighted many decades ago in the cosmetic chemistry community. First extensive insights were probably those of Meinecke (4), who reported that addition of a protein hydrolysate or a protein-fatty acid condensate to a solution of a highly irritant surfactant (sodium alkylbenzene sulfonate) caused a remarkable increase in the skin tolerability of the product and postulated a protective effect based on the formation of a protein colloidal layer on the skin, which could prevent or minimize the direct interaction of tenside molecules with skin keratin. The same interpretation has been advanced more recently by other authors (116-118). 

Soluble native proteins, protein hydrolysates, and fatty acid condensates are sometimes used to improve and refine the physicochemical properties of cosmetic formulations. Many... 

Anionic A-acylated L-amino acids, oligopeptides, and protein hydrolysates can be used in the wool finishing process. An increased bath exhaustion and a more intense coloration of wool were obtained during the dyeing of wool by the addition of A-acyl-L-amino acids or commercially available protein-fatty acid condensates [70],... 

The use of proteins as raw material for personal and home care products has been known for more than 60 years [58]. Both animal (e.g. leather waste) and plant-based proteins are available as raw materials. Nowadays mostly plant-based proteins (e.g. from wheat, soya bean, rice, peas) are used. Typically the natural proteins are degraded by hydrolysis (either chemically or enzymatically) and the respective protein hydrolysates are obtained. After purification and work-up they are used for skin and hair care formulations. The main claims are protection and care for hair and skin. Subsequent quarternization of the protein hydrolysates leads to products with high substantivity and conditioning effects, whereas acylation of the protein hydrolysates with fatty acids results in protein surfactants, the so-called protein fatty acid condensates. In the latter case, as already described for the sugar-based surfactants, the products are based completely on natural raw materials, namely fatty acids (from vegetable oil) and the protein or protein hydrolysate as the hydrophilic part in the surfactant molecule (Figure 4.6). The... 

In analogy to the well-known condensation products of fatty acids with protein hydrolysates, a patent has also been initiated for the condensation products of ether carboxylic acids and protein hydrolysates [43]. They are made by converting the ether carboxylic acids with thionyl chloride (SOCl2) to the corresponding acid chlorides followed by the condensation with a protein hydrolysate. 

Condensation products of fatty acid halides and protein hydrolysates are produced now in a wide range as secondary surfactants for the same needs. They may be modified additionally by quatemisation to gain more cationic nature as mentioned in the previous paragraph. The number of amino acids attached varies over a wide range whereas their morphological state... 

Syn. Fatty Acid-Protein Condensates Acylated Protein Hydrolysates... 

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