Progesterone T

Alza Corp. has also developed an iatrauteriae device, Progestasert, designed to release progesterone [57-83-0] by diffusion through a rate-controlling membrane for up to one year. The dmg reservoir is built into a T-shaped device that is inserted intravaginaHy (15). 

Kim, I.Y., Han, S.Y., and Kang, T.S. et al. (2005). Pyrethroid insecticides, fenvalerate and permethrin, inhibit progesterone-induced alkaline phosphatase activity in T47D human breast cancer cells. Journal of Toxicology and Environmental Health—Part A—Current Issues 68, 2175-2186. 

Watanuki, H., Yamaguchi, T., and Sakai, M. (2002). Suppression in function of phagocytic cells in common carp Cyprinus carpio L. injected with estradiol, progesterone or 11-ketotestosterone. Comparative Biochemistry and Physiology C—Toxicology and Pharmacology 132, 407 13. 

Breskvar K, T Hudnik-Plevnik (1977) A possible role of cytochrome P-450 in hydroxylation of progesterone by Rhizopus nigricans. Biochem Biophys Res Comm 74 1192-1198. 

Fig. 20.8. P -gp-ATPase activation profiles obtained by measurements of extracellular acidification rates in living cells by means of a cytosensor physiometer. (A) Cyclosporin A ( ), progesterone (0)> trifluoperazine (A) and verapamil ( ) in LLC-MDR1 cells (B) amitriptyline ( ), calcein-AM (A), diltiazem ( ) and vinblastine (T) in LLC-MDR1 cells.

Birnbaumer, M.E., Schrader, W.T., and O Malley, B.W. (1979) Chemical cross-linking of chick oviduct progesterone-receptor subunits using a reversible bifunctional cross-linking agent. Biochem. /. 181, 201-213. 

Fig. 17. Chromatographic confirmation of the imprinting effect. Applying (top) polymer ( anti-1 MIP ) imprinted with 11-a-hydroxyprogesterone ( T ),and (bottom) polymer ( anti-9 MIP ) imprinted with 11-deoxycortisol ( 9 ). Component 4 progesterone. Reprinted with permission from Ye L, Yu Y, Mosbach K (2001) Analyst 126 (Advance Article). Copyright 2001 The Royal Society of Chemistry... 

Bixo M, Backstrom T, Winblad B. 1984. Progesterone distribution in the brain of the PMSG treated female rat. Acta Physiol Scand 122(3) 355-359. 

Hiroi T, Kishimoto W, Chow T, Imaoka S, Igarashi T, et al. 2001. Progesterone oxidation by cytochrome P450 2D isoforms in the brain. Endocrinology 142 3901-3908. 

Rose JE, Levin ED (1991) Inter-relationships between conditioned and primary reinforcement in the maintenance of cigarette smoking. Br J Addict 86(5) 605-609 Rosecrans JA (1971) Elfects of nicotine on brain area 5-hydroxytryptamine function in male and female rats separated for differences of activity. Eur J Pharmacol 16(1) 123-127 Rosecrans JA (1972) Brain area nicotine levels in male and female rats with different levels of spontaneous activity. Neuropharmacology ll(6) 863-870 Rosecrans JA, Schechter MD (1972) Brain area nicotine levels in male and female rats of two strains. Arch Int Pharmacodyn Ther 196(l) 46-54 Saigusa T, Takada K, et al (1997) Dopamine efflux in the rat nucleus accumbens evoked by dopamine receptor stimulation in the entorhinal cortex is modulated by oestradiol and progesterone. Synapse 25(1) 37 3... 

Numan, M., Roach, J.K., del Cerro, M.C., Guillamon, A., Segovia, S, Sheehan, T.P., and Numan, M.J. (1999) Expression of intracellular progesterone receptors in rat brain during different reproductive states, and involvement in maternal behavior. Brain Res 830 358-371. 

Lydeking-Olsen E, Beck-Jensen JE, Setchell KD, Holm-Jensen T. Soymilk or progesterone for prevention of bone loss a 2 year randomised, placebo-controlled trial. Eur. J. Nutr. 43, 246-257, 2004. 

Ruotsalainen S, Miettinen R, MacDonald E, et al The role of the dorsal raphe-serotonergic system and cholinergic receptors in the modulation of working memory. Neurosci Biobehav Rev 22 21-31, 1998 Rupprecht R, ReulJMHM, Trapp T, et al Progesterone receptor-mediated effects of neuroactive steroids. Neuron 11 523-530, 1993 Rush AJ, Beck AT, Kovacs M, et al Comparative efficacy of cognitive therapy and pharmacotherapy in the treatments of depressed outpatients. Cognitive Therapy Research 1 17-37, 1977... 

T Cortisol, corticosterone. aldosterone 1 T Thyroxine, (T, triiodothyronine (T3) I i i Progesterone, estradiol Testosterone 1 1... 

Uses Breast/endometrial CAs appetite stimulant in cachexia (CA HIV) Action Hormone progesterone analog Dose CA 40-320 mg/d PO in + doses Appetite 800 mg/d PO + dose Caution [X, -] Thromboembolism Contra PRG Disp Tabs, soln SE DVT edema, menstrual bleeding photosens, insomnia, rash, 4- BM Interactions T Effects OF warfarin EMS T Risk of CV problems, esp in smokers T effects of warfarin may T glucose T risk of photosensitivity Rxns OD Unlikely to cause life-threatening Sxs... 

Wihlback A-C, Nyberg S, Backstrom T, Bixo M, Sundstrom-Poromaa I. Estradiol and the addition of progesterone increase the sensitivity to a neurosteroid in postmenopausal women. Psychoneuroendocrinology 2005 30 38-50. 

Andreen L, Bixo M, Nyberg S, Sundstrom-Poromaa I, Backstrom T. Progesterone effects during sequential hormone replacement therapy. Eur J Endocrinol 2003 148 571-7. 

Suzuki R, Matsumura Y, Kambe N, Fujii H, Tachibana T, Miyachi Y. Erythema multiforme due to progesterone in a low-dose oral contraceptive pill. Br J Dermatol 2005 152 370-1. 

Oyaizu, T., Arita, S., Hatano, T., and Tsubura, A. 1996. Immunohistochemical detection of estrogen and progesterone receptors performed with an antigen-retrieval technique on methacam-fixed paraffin-embedded breast cancer tissues. J. Surg. Res. 60 69-73. 

Perrot-Applanat, M., Groyer-Picard, M.-T., Vu Hai, M. T., Pallud, C., Spyratos, F., and Milgrom, E. 1989. Immunocytochemical staining of progesterone receptor in paraffin sections of human breast cancers. Am. J. Pathol. 735 457-468. 

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