Potential research

The committee recommends that a steady-state program of 15 research excellence awards in chemical engineering be achieved over 3 years. This new mechanism is described in Chapter 10. Because these awards are intended to fund speculative high-potential research, they will probably work best in the milieu of a small research group. Thus, the committee recommends that they be funded at about Level D. The steady-state cost of the initiative would be 1.5 million. 

By using the simulation model developed in Samsung Total we applied the ideas of pFoductivily enhancement successfiiUy to LDPE plant and accomplished considerable productivity incn e. The MWD as well as the melt index and density calculated by the simulation model convinced us of applying the ideas to commercial plant. The end user property prediction capabilities of the model will be refined further by integration of phj icxjchemical and statistical approaches and be one of the next potential research items. 

Minimal information about these agents or potential research programs concerning these agents has been published in the unclassified literature. There is no information to indicate that these agents were ever stockpiled or have ever been used on the battlefield. 

Specific (local tissue tolerance) toxicity studies may be necessary due to special characteristics of the product or the clinical indication. Adjuvanted vaccines are routinely evaluated for local (injection site) reactions, and cellular therapies are routinely screened for tumorigenic potential. Research is also needed to better predict the sensitizing potential of biological products and to determine the relevance of serum antibody levels following repeat dosing in animals and humans. 

The governing rules and regulations require cerfain elemenfs (information) be included wifhin every informed consenf form fhaf is provided to a potential research participant. These required elements are outlined in Table 22.2. 

It s exciting that there are so many topics and individuals out there that have potential research interest. Your research topic may be chosen for you if you are in a particular class, but often you will have to come up with a topic by yourself. How do you narrow down your topics or choose just one idea For the moment, you don t have to answer that question. Instead, allow yourself to brainstorm and make a list of at least potential ideas or people that might interest you. For instance, your list might look something like this ... 

The principle of autonomy entails that persons should be treated as inherently valuable individuals with the moral right to make decisions about their own lives. To the extent that one s actions and choices do not negatively affect others, individuals with the capacity to make their own decisions should be free to do as they wish, even if their choices are risky or harmful to themselves. The principle also entails that persons with diminished autonomy, such as those who are illiterate or retarded, deserve to have their interests protected. Many moral obligations for professionals engaged in scientific research or health care are derived from the principle of autonomy, such as the physician-researcher s obligation to fully inform potential research subjects and respect the individual s informed consent or informed refusal. This obligation is founded on the principle that individuals are the appropriate decision makers for choices that do not harm others. 

In Chapter 3 of this report, the committee presents a systematic framework or matrix to characterize the properties of biomarkers as a means to inform scientists and the general public about biomarkers and their significance in biomonitoring studies. The framework generally summarizes what is known about a biomarker and indicates potential research gaps that need to be addressed to meet the requirements for some specific uses. 

However, biomarkers are being used even when there is little information on exposure or health effects. The classification of biomarkers described in Chapter 3 provides a useful framework for thinking about the characteristics of biomarkers that make them relevant and useful for various applications and provides an important assessment of potential research gaps. 

Obvious areas of potential research present themselves to the forensic chemist. 

Since photoelectrochemical hydrogen production is in an embryonic stage, a parallel effort to reduce the cost of electricity production from PV modules must be made. A substantial reduction in PV module cost (lower than 0.5/Wp) coupled with similar reductions in electrolyzer costs (about 125/kW at reasonable high efficiency of about 70 percent on a lower heating value basis) can provide hydrogen at reasonable cost. The potential research opportunities listed in the preceding subsection for PV solar cells along with electrolyzers must be actively explored. 

Winneke, G., G.Fodor, and H.Schlipkoter. 1978. Carbon monoxide, trichloroethylene, and alcohol reliability and validity of neurobehavioral effects. Pp. 461-469 in Multidisciplinary Perspectives in Even-Related brain Potential Research, Proceedings of the Fourth International Congress on Event-Related Slow Potentials of the Brain (EPICIV), Univ. of NC and U.S. EPA, Hendersonville, NC, April 4—10, 1976, D.P.Otto, ed. EPA-600/9-77-043. Research Triangle Park, NC U.S. Environmental Protection Agency. 

If you have doubts about the accuracy of any material you discover on the Internet, find another authoritative source to validate the information or omit it from your essay. Following the guidelines on pages 381-383 will help you evaluate all your potential research sources. 

Furthermore, the synthesis, spectroscopy, electrochemistry, and magnetic studies of chromium(III) derivatives of hexose recently reported (442) showed the possibility of potential research activity in transition metal saccharide chemistry in the near future. 

Another example of a potential conflict of interest is the use of finder s fees to help to identify research subjects. A finder s fee is a fee paid to individuals, usually nurses, physicians, and pharmacists, who assist in locating potential research subjects. It may not be wrong to offer such a fee, but it is probably wrong for investigators to demand it. It would be unethical to deny a patient the opportunity to benefit from a study simply because the investigator would not receive the money. In lieu of paying finder s fees directly, some institutions... 

Stimulating discussions with C. M. Marcus are gratefully acknowledged. This work was supported by the Stichting voor Fundamenteel Onderzoek der Materie (FOM), and by the EU s Human Potential Research Network under contract No. HPRN-CT-2002-00309 ("QUACS"). 

We cannot really count on serendipity to discover new leads in modern medicinal chemistry, and a whole battery of tools has been developed to help identify new and promising compounds. One major obstacle in lead generation is how to discriminate among hundreds of different compounds in order to find the one that has the most potential. Researchers utihze different screens or assays in order to do this. In vitro assays (outside of the organism) are faster and less expensive to perform. These kinds of tests are often roboticized and can therefore be performed very quickly with many different leads. 

Potential research topics. Because of their steroidal structure, the brassinosteroids offer many potential avenues for research both in phytochemistry and zoochemistry. If, for example, the presence of the brassinosteroids is relatively ubiquitous in plants, is it then possible that they play a role in host parasite relationships It is of note that many plant parasitic and intestinal nematodes must obtain their cholesterol precursors from their respective hosts (18), a paradigm of the former being the plant gall inducing nematode Ditylenchus dipsaci and of the latter the somewhat large intestinal nematode Ascaris lumbricoides. Certain phytopathogenic fungi also have a sterol requirement for completion of their life cycle (19), as do certain insects (20). 

Unpublished discussions with Professor Joel P Liebman, who places occult chemistry in the realm of arts and seances and further suggests the National Seance Foundation as a potential research funding source. 

High performance liquid chromatography (HPLC), the fluorometric-iodine method (FL-IM), the enzyme-linked immunosorbent assay (ELISA), the solid-phase radioimmunoassay (RIA), and the tandem mass spectrometer, all have great potential. Research is needed to determine the extent, limitations, and applications for each method. 

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