Polyhydroxyalkanoates industrial production

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Chen GQ, Zhang G, Park SJ, Lee SY (2001) Industrial production of poly(hydroxybutyrate-ct>-hydroxyhexanoate). Appl Microbiol Biotechnol 57 50-55 Chen JY, Liu T, Zheng Z, Chen JC, Chen GQ (2004) Polyhydroxyalkanoate synthases PhaCl and PhaC2 from Pseudomonas stutzeri 1317 has different substrate specificities. FEMS Microbiol Lett 234 231-237... 

Industrial Production of Bacterial Polyhydroxyalkanoates PHAs via Fermentation... 

Figure 16.5 Strain and process development for industrial production of polyhydroxyalkanoates...

Van Wegen RJ, Ling Y, Middelberg APJ (1998) Industrial production of polyhydroxyalkanoates Mwag Escherichia coir, an economic analysis. ChemEng Res Des 76(3) 417 26. doi 10.1205/ 026387698524848... 

Abstract Many types of fermentation feedstock have been studied for the production of polyhydroxyalkanoate (PHA). Several industrial-scale processes have been developed for PHA production from sugars. Sugars are attractive feedstock because of their abundant supply worldwide, market stability, and also because the metabolism of PHA from sugars is very well understood. Recently, plant oils have been gaining much interest as a potential feedstock for PHA production. Industrial-scale processes for the production of PHA from plant oils are currently being developed. This chapter looks at the challenges in using plant oils, especially pahn oil as feedstock for PHA production. 

Abstract The most important aspect of any feedstock for industrial-scale production of polyhydroxyalkanoate (PHA) is market stability. One would expect the feedstock to be sustainable in terms of supply, cost and quahty. In addition, recently, there is also growing concerns over the use of food-grade feedstock for making nonedible products such as fuel and material. Therefore, the selection of a feedstock for PHA production must take into consideration the effect on global food supply. This chapter presents the current scenario of the palm oil industry along with issues such as land management and conservation of biodiversity. In order to ensure the sustainability of PHA production from palm oil, several strategies are proposed. 

Abstract Studies have shown that the production of polyhydroxyalkanoate (PHA) from plant oils is more efficient than from sugars in terms of productivity. Among the various plant oils, pahn oil is the most efficiently produced oil in the world. The main application of pahn oil is as a source of dietary fat. The conversion of food grade substrates to non-food materials is of concern because of the increasing need to feed the rapidly growing human population. Therefore, the by-products of the plant oil industry may be a better feedstock for PHA production. Alternatively, non-food grade oils such as jatropha oil can be developed as a feedstock for PHA production. This chapter looks at the potential of jatropha oil as a possible feedstock for the biosynthesis of PHA. 

Abstract Polyhydroxyalkanoate (PHA) initially received serious attention as a possible substitute for petrochemical-based plastics because of the anticipated shortage in the supply of petroleum. Since then, PHA has remained as an interesting material to both the academia and indusby. Now, we know more about this microbial storage polyester and have developed efficient fermentation systems for the large-scale production of PHA. Besides sugars, plant oils will become one of the important feedstock for the industrial-scale production of PHA. In addition, PHA will find new apphcations in various areas. This chapter summarizes the future prospects and the importance of developing a sustainable production system for PHA. 

Amirul AA, Yahya ARM, Sudesh K, Azizan MNM, Majid MIA (2008) Biosynthesis of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) copolymer by Cupriavidus sp. USMAA1020 isolated from lake Kulim. Malays Bioresour Technol 99 4903-4909 Anderson AJ, Dawes EA (1990) Occurrence, metabolism, metabolic role, and industrial uses of bacterial polyhydroxyalkanoates. Microbiol Rev 54 450-472 Anderson AJ, Haywood GW, Dawes EA (1990) Biosynthesis and composition of bacterial poly(hydroxyalkanoates). Int J Biol Macromol 12 102-105 Annuar MSM, Tan IKP, Ibrahim S, Ramachandran KB (2007) Production of medium-chain-length Poly(3-hydroxyalkanoates) from crude fatty acids mixture by Pseudomonas putida. Food Bioprod Process 85 104-119... 

A number of examples of biosystems engineering applied to industrial biotechnology (or industrial systems biology ) have been summarized by Papini et al. [105] and Wittmann [106], including examples for commercially highly important products such as ethanol, butanol, polyhydroxyalkanoates, amino acids, polyke-tides, and antibodies. 

Polyhydroxyalkanoates (PHA) are polymers synthesised by bacteria as intracellular carbon and energy sources. PHA are industrially produced by pure cultures psing as main substrates glucose and propionic acid. The major expenses in the PHA production are determined by the cost of substrate and extraction of polymer from inside the cells. ... 

Puiushothaman, M., Anderson, R., Narayana, S. and Jayaraman, V. (2001) Industrial byproducts as cheaper medium components influencing the production of polyhydroxyalkanoates (PHA) - biodegradable plastics. Bioprocess and Biosystems Engineering, 24, 131-136. 

King PP (1982) Biotechnology. An industrial view. J Chem Technol Biotechnol 32 2-8 Knothe G (2001) Historical perspectives on vegetable oil-based diesel fuels. Ind Oils 12 1103-1107 Koller M, Bona R, Braunegg G, Hermann C, Horvat P, Kroutil M, Martinz J, Neto J, Vaiila P, Pereira L (2005a) Production of polyhydroxyalkanoates from agricultural waste and surplus materials. Biomacromolecules 6 561-565... 

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