Polyethylene glycol grafting polymers/copolymers

Polyvinyl caprolactam- polyvinyl acetate-polyethylene glycol graft copolymer (SOLUPLUS ) Polyvinyllactam polymers Nonionic 70°C 118,000g/mol Water soluble High 19.4 250 °C Hot melt extrusion... 

Fine distribution and amorphization of the same drug could be achieved also by electrospinning process using polyvinyl caprolactam - polyvinyl acetate - polyethylene glycol graft copolymer (Soluplus) as polymer matrix [7],... 

Cespi, M., Casettari, L., Palmieri, G.F., Perinelli, D.R., Bonacucina, G. Rheological characterization of polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer (Soluplus ) water dispersions. Colloid. Polym. Sci. 292, 235 (2014)... 

II. B polyethylene glycol, ethylene oxide, polystyrene, diisocyanates (urethanes), polyvinylchloride, chloroprene, THF, diglycolide, dilac-tide, <5-valerolactone, substituted e-caprolactones, 4-vinyl anisole, styrene, methyl methacrylate, and vinyl acetate. In addition to these species, many copolymers have been prepared from oligomers of PCL. In particular, a variety of polyester-urethanes have been synthesized from hydroxy-terminated PCL, some of which have achieved commercial status (9). Graft copolymers with acrylic acid, acrylonitrile, and styrene have been prepared using PCL as the backbone polymer (60). 

It should be pointed out that the addition of substances, which could improve the biocompatibility of sol-gel processing and the functional characteristics of the silica matrix, is practiced rather widely. Polyethylene glycol) is one of such additives [110— 113]. Enzyme stabilization was favored by formation of polyelectrolyte complexes with polymers. For example, an increase in the lactate oxidase and glycolate oxidase activity and lifetime took place when they were combined with poly(N-vinylimida-zole) and poly(ethyleneimine), respectively, prior to their immobilization [87,114]. To improve the functional efficiency of entrapped horseradish peroxidase, a graft copolymer of polyvinylimidazole and polyvinylpyridine was added [115,116]. As shown in Refs. [117,118], the denaturation of calcium-binding proteins, cod III parvalbumin and oncomodulin, in the course of sol-gel processing could be decreased by complexation with calcium cations. 

A polyethylene glycol-polystyrene graft copolymer palladium catalyst has been used in allylic substitution reactions of allyl acetates with various nucleophiles in aqueous media.58 Another polymer-bound palladium catalyst 40 was developed and used in a Heck coupling of allylic alcohols with hypervalent iodonium salts to afford the substituted allylic alcohols as the sole products under mild conditions with high catalytic efficiency.59 The same polymer-bound palladium catalyst has also been used for Suzuki cross-coupling reactions.60... 

Radical transfer reactions involving poly ethers of the poly (ethylene oxide) type are well known (7). Heating polyethylene glycols of various molecular weights at 140 °C. with dicumyl peroxide for 2.5 hours has resulted in a gel fraction explained by transfer at the a-carbon followed by combination of the polymer radicals. Further, poly (ethylene oxide) dissolved in MMA and heated in the presence of benzoyl peroxide results in grafted copolymer. 

Graft copolymers were prepared by both classical strategies, that is, from enzymatically obtained macromonomers by subsequent chemical polymerization and by enzymatic grafting from hydroxyl functional polymers. Kalra et al. studied the synthesis of PPDL graft copolymers from macromonomers, which were obtained by the enzymatic ROP of pentadecalactone (PDL) from hydroxyethyl methacrylate (HEMA) and polyethylene glycol) methacrylate (PEGMA) [40]. Subsequently graft copolymers were obtained by free radical polymerization of the macromonomers. A similar approach was published by Srivastava for the HEMA-initiated enzymatic ROP of CL and subsequent free radical polymerization [41]. 

Polystyrene resin, frequently used resin material for solid-phase peptide synthesis (SPPS). The polymeric support for SPPS must be chemically inert, mechanically stable, completely insoluble in the solvents used, and easily separated by filtration. For many applications a copolymer of polystyrene with 1% of divinyl benzene as crosslinker is used. The dry resin beads are able to swell up to the five-or sixfold volume in the different organic solvents mainly used for peptide synthesis (e.g., dichloromethane or dimethylfor-mamide). For SPPS the resin material must be chemically functionalized in order to allow for attachment of a handle/liker (e.g. Wang resin), or the first amino acid (—> Merrifield resin). Hydrophilic tentacle polymers gels (TentaGel) are obtained by grafting polyethylene glycol (PEG) chains with an arbitrary degree of polymerization onto porous polystyrene beads. 

Sun, Y., Hoffman. A. S., and Gombotz, W. R.. Non-fouling biomaterial surfaces II. Protein adsorption on radiation grafted polyethylene glycol methacrylate copolymers, Polym. Prep., 25(1) 292 (1987). 

Tg measurements have been performed on many other polymers and copolymers including phenol bark resins [71], PS [72-74], p-nitrobenzene substituted polymethacrylates [75], PC [76], polyimines [77], polyurethanes (PU) [78], Novolac resins [71], polyisoprene, polybutadiene, polychloroprene, nitrile rubber, ethylene-propylene-diene terpolymer and butyl rubber [79], bisphenol-A epoxy diacrylate-trimethylolpropane triacrylate [80], mono and dipolyphosphazenes [81], polyethylene glycol-polylactic acid entrapment polymers [82], polyether nitrile copolymers [83], polyacrylate-polyoxyethylene grafts [84], Novolak type thermosets [71], polyester carbonates [85], polyethylene naphthalene, 2,6, dicarboxylate [86], PET-polyethylene 2,6-naphthalone carboxylate blends [87], a-phenyl substituted aromatic-aliphatic polyamides [88], sodium acrylate-methyl methacrylate multiblock copolymers [89], telechelic sulfonate polyester ionomers [90], aromatic polyamides [91], polyimides [91], 4,4"-bis(4-oxyphenoxy)benzophenone diglycidyl ether - 3,4 epoxycyclohexyl methyl 3,4 epoxy cyclohexane carboxylate blends [92], PET [93], polyhydroxybutyrate [94], polyetherimides [95], macrocyclic aromatic disulfide oligomers [96], acrylics [97], PU urea elastomers [97], glass reinforced epoxy resin composites [98], PVOH [99], polymethyl methacrylate-N-phenyl maleimide, styrene copolymers [100], chiral... 

Wacker-Belsil DM 100000 [Wacker-Chemie GmbH http //www.wacker.de], WorleeAdd 374 [Worlee-Chemie http //www.worlee.de] Dimethicone copolyol CAS 64365-23-7 68937-54-2 68938-54-5 Synonyms Dimethyl methyl (polyethylene oxide) siloxane Dimethylsiloxane/glycol copolymer Polyoxyethylene-grafted polydimethylsiloxane Polysiloxane polyether copolymer Siloxanes and silicones, dimethyl, hydroxy-terminated, ethoxylated propoxylated Classification Silicone glycol surfactant Definition Polymer of dimethylsiloxane with polyoxyethylene and/or polyoxypropylene side chains... 

Jannasch (2001) grafted a PEO side chain onto the polyethylene chain, leading to the ion conductivity increasing to 3.2 x 10 S/cm at room temperature after doping with LiTFSI. In addition, they also prepared a branch polyacrylate copolymer where the side chain is composed of poly(ethylene glycol) (PEG), and alkane or fluorinated alkane (Gavelin et al, 2002). As the resulting polymer is amorphous, the ion conductivity reached 8 x 10- S/cm. 

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