Peripheral human

Although controversial, findings as to how chronically administered morphine modulates neutrophil chemotaxis and function, a growing consensus believes that morphine is suppressive in the recruitment and functional aspects of these cells during an innate immune response. When peripheral human blood neutrophils were pretreated with exogenous opioids, lL-8-induced chemotaxis was inhibited (Grimm et al. 1998). Conversely, Simpkins et al. reported an increase in neutrophil chemotaxis... 

Rapp, L. M., S. S. Maple, and J. H. Choi. 2000. Lutein and zeaxanthin concentrations in rod outer segment membranes from perifoveal and peripheral human retina. Invest. Ophthalmol. Vis. Sci. 41 1200-1209. 

Correlation between NE inhibition in hen, guinea-pig and rat brain such as in lymphocytes from peripheral human blood has been found. It was concluded that NE activity may be used for delayed polyneuropathy screening of OPC. 

Ebato B, Friend J, Thoft RA. Comparison of limbal and peripheral human corneal epithelium in tissue culture. Invest Ophthalmol Vis Sci 29 1533-1537 (1988). 

Lecoeur H, Ledru E, Prevost M-C, Gougeon M-L. 1997. Strategies for phenotyping apoptotic peripheral human lymphocytes comparing ISNT, annexin-V and 7-AAD cytofluorometric staining methods. J Immunol Methods 209 111-123. 

At concentrations of 10 and 100p,g/ml, calcium silicate significantly increased the frequencies of chromosomal aberrations and sister chromatid exchanges in peripheral human blood lymphocytes. ... 

Ethylene dibromide gave rise to micronuclei in binucleated peripheral human lymphocytes after a 4-h exposure, whereas a comparable effect in mononucleated cells was observed only after continual exposure. 

Musso NR, Brenci S, Setti M, Indiveri F, Lotti G (1996) Catecholamine content and in vitro catecholamine synthesis in peripheral human lymphocytes. J. Clin. Endocrinol. Metab. 81 3553-3557. 

R. Die Water, L. N. A. Willems, G. N. P. van Muijen, C. Franken, I. A. M. Fran sen, J. H. Dijiutum, nod j. A. Kramps. ultra structural localization of branchial amiieuko-protease in central and peripheral human airways by a gold-labeling technique using monoclonal antibodies. Am. Rev. Resp. Die. 133 882 (1986). 

Barten MJ, Dhein S, Chang H, et al. Assessment of immunosuppressive drug interactions inhibition of lymphocyte function in peripheral human blood. J Immunol Meth 2003 283(l-2) 99-114. 

The contact angles of peripheral human neutrophils from different donors tend to vary between these values. 

AUeigen-specific peripheral human T cell clones commonly have a ThO profile as do some of those from the skin of atopic dermatitis patients (Van Reijsen etal.,... 

The compounds SbCls and SbClf were reported to be genotoxic in the rec-assay with B. subtilis. Sb(III)ac-etate enhanced the Simian-Adenovirus-7-mediated transformation of SHE-cells, and enhanced rates of chromosomal breaks in human leukocytes were reported after treatment with potassium antimony tartarate (APT). SbCl3 did not induce DNA/pro-tein-crosslinks in V79-cells and peripheral human lymphocytes. 

B1. Baird, D. T., A method for the measurement of estrone and estradiol-17(S in peripheral human blood and other biological fluids using S pipsylchloride. J. Clin. Endocrinol. 28, 244-258 (1968). 

While some of the putative H. pylori carbohydrate receptor sequences are found in a variety of human cells, some have hitherto not been identified in human tissues. An example of the latter group is isoglobotriaosylceramide, which has been characterized in, e.g., dogs, cats, and rats, but not in humans. Similarly, gangliotriaosylce-ramide or gangliotetraosylceramide have not been chemically identified in peripheral human tissues. 

T. E. (2003) Biotransformation of 4-(methylnitrosamino)-l-(3-pyridyl)-l-butanone (NNK) in peripheral human lung microsomes. Drug Metab. Dispos. 31 (9), 1134 1141. 

For a long time, the major interest in tryptophan metabolism has been focused on the well-known neurotransmitter 5-hydroxytryptamine which, however, accounts for only 1% of dietary tryptophan metabolism in peripheral human tissues, more than 95% being transformed via the kynurenine pathway. Nowadays, a renewed interest arises as far as kynurenine and related substances is concerned, for example as potential targets for pharmacological therapies [5]. Therefore, it seems well worthwhile to carry out a somewhat detailed discussion about some aspects of the kynurenine pathway enzymology. The whole subject has been recently reviewed [5]. 

Nadhnger, K., Birkmayer, J., Gebauer, F., and Kunze, R., Influence of reduced nicotinamide adenine dinucleotide on the production of interleukin-6 by peripheral human blood leukocytes, Neuroimmunomodulation, 9, 203, 2001. 

Bertens, A.M.C. (2000) Evaluation of the ability of linalyl acetate to induce chromosomal aberrations in cultured peripheral human lymphocytes. Unpublished report prepared by NOTOX B.V., s-Hertogenbosch, Netherlands, for the Flavor and Extract Manufacturers Association, Washington, DC, USA. Submitted to WHO by the International Organization of the Flavor Industry, Brussels, Belgium (NOTOX Project No. 289968). 

LTC4, LTD4 and LTE4 (possibly also the 1 -trans isomers) fulfill two iihportant biological criteria previously attributed to the pathophysiological agent SRS-A, i.e. the potent smooth muscle effects preferentially in peripheral human airways and the marked increase of vascular permeability in the venules. 

Verhagen H, de Vries A, Nijhoff WA, et al. Effect of Brussels sprouts on oxidative DNA-damage in man. Cancer Lett. 1997 114 127-130. Hoelzl C, Glatt H, Meinl W, et al. Consumption of Brussels sprouts protects peripheral human Ijnnphocytes against 2-amino-l-methyl-6-phenylimidazo[4,5-b]pyridine (PhlP) and oxidative DNA-damage results of a controlled human intervention trial. Mol Nutr Food Res. 2008 52 330-341. 

Employing the conventional proliferation assay using lymphocytes isolated from spleen (mouse, rat), lymph nodes (mouse, rat), or peripheral human blood and... 

The carpofen (198) group of antiinflammatory substances (50) have been shown to have phototoxic properties involving skin photosensitivity (75). They induce uv dependent histamine and leucotriene release in peripheral human leucocytes. In vitro cellular effect of corpofen was... 

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