Parathion, Liquid

DOT/UN/NA/IMCO shipping Methyl parathion, liquid (DOT) Methyl parathion mixture, dry (DOT) methyl parathion, solid (DOT) UN 3017 organophosphorus pesticides, liquid, toxic, flammable, not otherwise specified HSDB 1999 RTECS 1989... 

Paraformaldehyde Para Hydrogen Para-Mentha-1,8 -Diene Paramoth Paranaphthalene Parathion, Liquid... 

PARATHION, LIQUID 0,0-Dlethyl-(p-nitrophenyl) Phospliorothioate, Piiosphorothioic Acid, Etliyl Parathion Poisonous, Class B, I 4 1 2 ... 

PHENOL P-NITRO- 0-ESTER WITH 0-DIETHYL PHOSPHOROTHIOATHE PHENOL, P-NITRO-, 0-ESTER WITH O.O-DIETHYL PHOSPHOROTHIOATHE PHOSPHOROTHIOIC ACID 0,0-DIETHYL O-(4-NITROPHENYL)ESTER PHOSPHOROTHIOIC ACID 0,0-DIETHYL O-(P-NITROPHENYL)ESTER P-NITRO-O-ESTER DE FENOL, CON FOSFOTIOATO DE O O-DIETILO PHOSPHOROTHIOIC ACID, 0,0-DIETHYL 0-(4-NITR0PHENYL) ESTER PARATHION LIQUID (USA)... 

Synonyms AAT AATP Diethyl-p-nitrophenyl monothiophosphate 0,0-Diethyl-0-4-nitrophenyl phosphorothioate 0,0-Diethyl-0-p-nitrophenyl phosphorothioate Diethyl-p-nitrophenylthionophosphate 0,0-Diethyl-p-nitrophenyl thiophosphate Diethyl parathion DNTP Ethyl parathion p-Nitrophenol, 0-ester with 0,0-diethylphosphorothioate Oleoparathion Parathion-ethyl Parathion liquid Phosphorothioic acid, 0,0-diethyl 0-(4-nitrophenyl) ester... 

Copper Naphthenate Oils Edible. Palp Oils Edible. Palp Oils Edible, Tucup Phthalic Anhydride Polymethylene Polyphenyl Isocyanate P-Dichlorobenzene P-Dichlorobenzene P-Dichlorobenzene Paraformaldehyde Hydrogen, Liquefied Cipentene P-Dichlorobenzene Anthracene Parathion, Liquid Methyl Parathion P-Xylene... 

Parathion, Liquid Polybutene Polychlorinated Biphenyl Polybutene Polychlorinated... 

Parathion, Liquid — Fire Hazards Flash Point (deg. F) Not flammable Flammable Limits in Air (%) Not flammable Fire Extinguishing Agents Water o adjacent fires Fire Extinguishing Agents Not to be Used High pressure water hoses may scatter parathion firom broken containers, increasing contamination hazard Special Hazards of Combustion Products Fumes from decomposing material may contain oxides of sulfur and... 

Methyl parathion is a pesticide that is used to kill insects on crops. Usually, it is sprayed on the crops. Methyl parathion comes in two forms a pure form of white crystals and a technical-grade solution (brownish liquid), which contains methyl parathion (80%) and inactive ingredients in a solvent. The technical-grade methyl parathion smells like rotten eggs or garlic. Methyl parathion is a manufactured chemical, so it is found in the environment only as a result of its manufacture or use. Methyl parathion has been manufactured in the United States since 1952 and has been used to kill insects on many types of crops since this time. Because methyl... 

A 50-year-old white male died after intentional methyl parathion ingestion (Wofatox liquid) (Fazekas and Rengei 1964). The estimated dose of methyl parathion was 1,840 mg. Gross necropsy findings consisted... 

Methyl parathion is marketed as a technical grade solution (80% methyl parathion) or in emulsifiable concentrate, wettable powder, ultra-low volume (ULV) liquid, dustable powder, and encapsulated suspension forms (HSDB 1999). The technical grade solution contains 80% active ingredient, 16.7%... 

A recent method, still in development, for determining total 4-nitrophenol in the urine of persons exposed to methyl parathion is based on solid phase microextraction (SPME) and GC/MS previously, the method has been used in the analysis of food and environmental samples (Guidotti et al. 1999). The method uses a solid phase microextraction fiber, is inserted into the urine sample that has been hydrolyzed with HCl at 50° C prior to mixing with distilled water and NaCl and then stirred (1,000 rpm). The fiber is left in the liquid for 30 minutes until a partitioning equilibrium is achieved, and then placed into the GC injector port to desorb. The method shows promise for use in determining exposures at low doses, as it is very sensitive. There is a need for additional development of this method, as the measurement of acetylcholinesterase, the enzyme inhibited by exposure to organophosphates such as methyl parathion, is not an effective indicator of low-dose exposures. 

In a study of the metabolism of methyl parathion in intact and subcellular fractions of isolated rat hepatocytes, a high performance liquid chromatography (HPLC) method has been developed that separates and quantitates methyl parathion and six of its hepatic biotransformation products (Anderson et al. 1992). The six biotransformation products identified are methyl paraoxon, desmethyl parathion, desmethyl paraoxon, 4-nitrophenol, />nitrophenyl glucuronide, and /wiitrophenyl sulfate. This method is not an EPA or other standardized method, and thus it has not been included in Table 7-1. 

Abe T, Fujimoto Y, Tatsuno T, et al. 1979. Separation of methyl parathion and fenitrothion metabolites by liquid chromatography. Bull Environ Contam Toxicol 22 791-795. 

Clark GJ, Goodin RR, Smiley JW. 1985. Comparison of ultraviolet and reductive amperometric detection for determination of ethyl and methyl parathion in green vegetables and surface water using high-performance liquid chromatography. Anal Chem 57 2223-2228. 

Jaglan PS, Gunther FA. 1970. Single column gas liquid chromatography of methyl parathion and metabolites using temperature programming. Bull Environ Contam Toxicol 5 111-114. 

Jaglan PS, March RB, Fukuto TR, et al. 1970. Gas-liquid chromatographic determination of methyl parathion and metabolites. J Agric Food Chem 18 809-813. 

Koen JG, Huber JF. 1970. A rapid method for residue analysis by column liquid chromatography with polarographic detection Application to the determination of parathion and methyl parathion on crops. Anal Chim Acta 51 303-307. 

To illustrate the results obtained by this method, a few data are selected from investigations on the contamination of chicken flesh with 7-hexachlorocyclohexane and of cabbage with parathion. These cases are especially interesting because with the chicken flesh the liquid fats alter contact with the hexachlorocyclohexane and also cause considerable mortality of flies and because with cabbage chemical analysis of parathion is difficult on account of very high blanks with untreated samples when the usual colorimetric method is used. 

Parathion (0,0-diethyl 0-p-nitrophenyl thiophosphate) is an ester of thiophosphoric acid with the empirical formula C10H14NO5PS. It is a high boiling deep-brown to yellow liquid, some samples of which possess a characteristic odor. Its boiling point has been calculated to be 375 0 C. or higher, at 760 mm. pressure its refractive index is n 5 1.15360 specific gravity is 1.26. The vapor pressure is 0.0006 mm. of mercury at 24° C. The technical grade has a purity of approximately 95%. 

The purified tetraethyl pyrophosphate is a colorless, odorless, water-soluble, hygroscopic liquid (24, 4 )- It possesses a very high acute toxicity (28), exceeding that of parathion, and is rapidly absorbed through the skin. There is no spray-residue problem, however, for tetraethyl pyrophosphate hydrolyzes even in the absence of alkali to nontoxic diethyl phosphoric acid. Hall and Jacobson (24) and Toy (47) have measured its rate of hydrolysis, which is a first-order reaction. Its half-life at 25° C. is 6.8 hours and at 38° C. is 3.3 hours. Coates (10) determined the over-all velocity constant at 25° C. k = 160 [OH-] + 1.6 X 10 3 min.-1 Toy (47) has described an elegant method for preparing this ester as well as other tetraalkyl pyrophosphates, based upon the controlled hydrolysis of 2 moles of dialkyl chlorophosphate ... 

In the adsorption with Tenax alone satisfactory results were obtained, while in the presence of mineral oil a considerable proportion of the organophos-phorus pesticides (particularly Malathion and Parathion-methyl) was not adsorbed and was recovered in the filtered water. This drawback can be overcome by adding a layer of Celite 545 which, in order to prevent blocking of the column, is mixed with silanised glass wool plugs. A number of analyses of surface and estuarine sea waters were carried out by this modified Tenax column and simultaneously by the liquid-liquid extraction technique. To some of the samples taken, standard mixtures of pesticides were also added, each at the level of 1 xg/l (i.e., in concentration from 13 to 500 times higher than that usually found in the waters analysed). One recovery trial also specifically concerned polychlorobiphenyls. The results obtained in these tests show that the two extraction methods, when applied to surface waters that were not filtered before extraction, yielded very similar results for many insecticides, with the exception of compounds of the DDT series, for which discordant results were frequently obtained. 

T.E.P.P. is a colourless, odourless, water-soluble toxic liquid, more toxic than parathion and rapidly absorbed through the skin. It is quickly hydrolysed, even in the absence of alkali, to the non-toxic diethyl hydrogen phosphate. It has found use as an aerosol to control pests on greenhouse vegetables and flowers, and is relatively free from residual toxicity hazards. 

Liquefied petroleum gas, see Butane, 2-Methylpropane Liquid ammonia, see Ammonia Lirohex, see Tetraethyl p3U ophosphate Lirothion, see Parathion... 

METHYL PARATHION Metron, MPT, Parldol, Alkron, Nitran, Wolfatox Poisonous Liquid or Solid, Class B, II 4 3 2... 

Liquid chromatography-APCI-MS with NI and PI was used for the trace determination of several OPPs in groundwater. The limit of quantification varied between 5 and 37 ng/L in PI. Under the NI mode of operation, only the parathion group (both parathions and fenitrothion) had a better sensitivity than with the PI mode, with quantitation limit of 5-15 ng/L, whereas the rest of the pesticides had 2-4 times higher limits as compared to those in PI mode (52). 

A few of the estimated 50,000 organophosphates are shown in Figure 7-6. Many of the organophosphates (echothiophate is an exception) are highly lipid-soluble liquids. Echothiophate, a thiocholine derivative, is of clinical value because it retains the very long duration of action of other organophosphates but is more stable in aqueous solution. Soman is an extremely potent "nerve gas." Parathion and malathion are thiophosphate insecticides that are inactive as such they are converted to the phosphate derivatives in animals and plants and are used as insecticides. 

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