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Osteosarcomas

Alkaline phosphatase from rat osteosarcoma has been purified by acetone pptn, followed by chromatography on DEAE-cellulose, Sephacryl S-200, and hydroxylapatite. [Nair et al. Arch Biochem Biophys 254 18 1987.]... [Pg.557]

RB1 Codes for the pRB protein, a master brake of Retinoblastoma, osteosarcoma, and bladder, small cell... [Pg.1279]

CNS leukemia (IT) Breast cancer NHL Osteosarcoma Head and neck cancer Bladder cancer Rheumatoid arthritis... [Pg.1409]

Vincristine (VCR, Oncovin) ALL HD NHL multiple myeloma breast cancer SCLC, KS brain tumors soft tissue sarcomas osteosarcomas neuroblastoma Wilms tumor... [Pg.1409]

Gillett NA, Hahn FF, Mewhinney JA, et al. 1985. Osteosarcoma development following single inhalation exposure to americium-241 in beagle dogs. Radiat Res 104 83-93. [Pg.238]

Okada K, Sakusabe N, Kobayashi A, Hoshi N, Sato K. Prevention of lung metastasis by intra-tumoural injection of Cepharanthin and staphylococcal enterotoxin B in transplantable rat osteosarcoma. Jpn J Cancer Res 1999 90 928-933. [Pg.165]

The immediate early gene product c-Fos (cellular feline osteosarcoma) has widely been used as a useful marker of neuronal activation. Fos, the protein encoded by the c-fos gene, is a transcription factor that triggers transcription in a cascade of cellular responses. To determine which neuron groups are involved in the response to PGD2 and/or adenosine, especially A2aR agonists, we examined Fos-immunoreactivity under these conditions (Scammell et al., 1998, 2001 Satoh et al., 1999). [Pg.374]

Cellular uptake of MTX in an MTX-LDH hybrid was quantified by flow cytometry with FITC-conjugated MTX (MTX-FTIC). Human osteosarcoma (HOS) cells (5 x 105/1 ml) were treated with 50 pg/mL of MTX-FITC and 112 pg/mL of MTX-FITC-LDH, where the concentration of MTX-FITC in MTX-FITC-LDH was adjusted to maintain an equivalent amount of free MTX-FITC treated. After 1, 2, and 5h, cellular uptake was about 55-fold higher for MTX-FITC-LDH than for free MTX-FITC, as determined by the remarkably high fluorescence intensity of MTX-FITC-LDH compared to free MTX-FITC (Figure 13.6). This is evidence that MTX delivery in cells is greatly enhanced by using the MTX-LDH hybrid. [Pg.409]

Beagle dog inhalation "CeCl, AMAD t.5-2,4 ion a, 1.6-2.1 13-16 mos 70 life span (in progress) death, bone marrow aplasia and pancytopenia, radiation pneumonitis, pulmonary fibrosis, hepatic necrosis 11/48 Yes pulmonary adenoma, bronchtogenic adenocarcinoma 3/48 Yes he man- Yes giocarcinoma osteosarcoma, 6/48 leukemia 3/34 (primary) Benjamin et al. (1972b 1976c) Merickel et al. (1978)... [Pg.56]

Beagle injection IV injection l44Ce citrate 13 mos 49 life span acute anemia, No number osteosarcoma, Ivanov (1963) Fritz ef ai (1970)... [Pg.57]

Muller, W.A., A.B. Murray, U. Linzner, and A. Luz. 1990. Osteosarcoma risk after simultaneous incorporation of the long-lived radionuclide 227Ac and the short-lived radionuclide 227Th. Radiation Res. 121 14-20. [Pg.1746]

Teriparatide is contraindicated in patients at baseline increased risk for osteosarcoma (e.g., Paget s bone disease, unexplained alkaline phosphatase elevations, pediatric patients, young adults with open epiphyses, or patients with prior radiation therapy involving the skeleton). [Pg.42]

MDP-PE, muramyl tripeptide phosphatidyl, Ethanolamine Lipoidal tripeptide Macrophage activating agent Osteosarcomas... [Pg.161]

Kleinerman, E.S., Biologic therapy for osteosarcoma using liposome-encapsulated muramyl tripeptide, Hematol. Oncol. Clin. North Am., 9, 927, 1995. [Pg.169]

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Cancer osteosarcoma

Fluoride osteosarcoma

Human osteosarcoma

In human osteosarcoma

Methotrexate osteosarcoma

Osteosarcoma cells

Osteosarcoma treatment

Osteosarcoma, radiation exposure

Osteosarcoma, role

Osteosarcoma-derived growth factor

Retinoblastoma, osteosarcoma

Small-cell osteosarcoma

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