Osteosarcoma cells

This HDAC inhibitor (Fig. 15) was isolated from a cyanobacterium Symplaca sp. collected from the Florida Keys. This depsipeptide was described by Leusch and coworkers in lOOSP It has been shown to be potent at low nanomolar ranges against mammary cancer cell lines MDA-MB-231, HT29 colon cancer cells, IMR-32 neuroblastoma cells and U20S fibroblastic osteosarcoma cells. ... 

Matsui TA, Murata H, Sakabe T, Sowa Y, Horie N, Nakanishi R, Sakai T, Kubo T. (2007) Sulforaphane induces cell cycle arrest and apoptosis in murine osteosarcoma cells in vitro and inhibits tumor growth in vivo. Oncol Rep 18 1263-1268. 

Miller AC, Kariko K, Myers CE, et al. Increased radioresistance of EJras-transformed human osteosarcoma cells and its modulation by lovastatin, an inhibitor of p21ras isoprenylation. Int J Cancer 1993 53 302-307. 

Walters DK, Muff R, Langsam B, Born W, Fuchs B. 2007. Cytotoxic effects of curcumin on osteosarcoma cell lines. Invest New Drugs 26 289-297. 

Cortizo, A.M., Bruzzone, L., Molinuevo, S., and Etcheverry, S.B. 2000. A possible role of oxidative stress in the vanadium-induced cytotoxicity in the MC3T3E1 osteoblast and UMR106 osteosarcoma cell lines. Toxicology 147, 89-99. 

Haskin, C. and Cameron, I. (1993) Physiological levels of hydrostatic pressure alter morphology and organization of cytoskeletal and adhesion proteins in MG-63 osteosarcoma cells. Biochemical Cell Biology 71 27-35... 

D3. Dey, R., and Moraes, C. T., Lack of oxidative phosphorylation and low mitochondrial membrane potential decrease susceptibility to apoptosis and do not modulate the protective effect of Bc1-xl in osteosarcoma cells. J. Biol. Chem. 275, 7087-7094 (2000). 

Krueger S, Haeckel C, Buehling F, Roessner A (1999) Inhibitory effects of antisense cathepsin B cDNA transfection on invasion and motility in a human osteosarcoma cell line. Cancer Res 59 6010-6014... 

Corbiere, C., Liagre, B., Bianchi, A., Bordji, K., Dauca, M., Netter, P. and Beneytout, J.L. (2003) Different contribution of apoptosis to the antiproliferative effects of diosgenin and other plant steroids, hecogenin and tigogenin, on human 1 547 osteosarcoma cells. International Journal of Oncology 22(4), 899-905. 

Other mitogenicity in CHO-K1 and human BIO osteosarcoma cells, human hepatoma cells and MCF-7 cells to include drug binding study to IGF-1 and insulin receptors local tolerance in pigs immunogenicity studies in rabbits... 

Whole-Cell Assays with Osteosarcoma Cells (COX-2) and U937 Cells (C0X-1)... 

The human osteosarcoma cell line has been shown selectively to express COX-2 by reverse transcription-polymerase chain reaction and immunoblot analysis, whereas undifferentiated human lymphoma U937 cells... 

Wong E, DeLucca C, Boily C et al. (1997) Characterization of autocrine inducible prostaglandin H synthase-2 (PGHS-2) in human osteosarcoma cells. Inflamm Res 46 51-59... 

The membrane-bound activity was obtained from crude homogenate of rat osteosarcoma cells. 

Franceschi RT, Romano PR, and Park KY (1988) Regulation of type I collagen synthesis by 1,25-dihydroxyvitamin D3 in human osteosarcoma cells. Journal of Biological Chemistry 263,18938-45. 

Recklles A D, White C, Melching L et al 2001 Differential regulation and expression of hyaluronan synthases in human articular chondrocytes, synovial cells and osteosarcoma cells. Biochemical Journal 354 17-24... 

These peptides were cytotoxic in p53-null cancer cells or in those having mutant or normal p53 [235]. In another study, a GST fusion peptide with the sequence MPRFMDYWEGLN was introduced into osteosarcoma cells that overexpressed mdm-2, and in other cell lines that expressed mdm-2 and p53 but were transformed by the HPV16 E6 oncogene [236]. This peptide also induced apoptosis in p5 3-containing cells, but not in cells with homozygous deletions of p53. 

Wiedlocha A, Falnes P0, Rapak A, Munoz R, Klingenberg O, Olsnes S (1996) Stimulation of proliferation of a human osteosarcoma cell line by exogenous acidic fibroblast growth factor requires both activation of receptor tyrosine kinase and growth factor internalization. Mol Cell Biol 16 270-280. 

MCP-2 -(GCL8),, Moiiocytes/macrophages Fibroblasts Osteosarcoma cells. T lymphocytes Monocytes Basophils/eosihophils NK cells, CCR3, CCR5... 

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