Nicotine sulphate

Alkaloids are usually basic and combine with acids to form alkaloid salts, a property often exploited to extract them from their source. Other alkaloids occur naturally as salts of organic acids. Common salts include hydrochlorides, salicylates, sulphates, nitrates, acetates, and tartrates such as morphine acetate, cocaine hydrochloride, and strychnine nitrate. Water, alcohol, and ether solutions of alkaloids and their salts are often used to administer or carry the alkaloid, particularly for medicinal purposes. Nicotine preparations can include a variety of liquid and solid mixtures of nicotine (soluble in alcohol, chloroform, ether, and water), nicotine salts, and many other nicotine compounds (e.g., nicotine sulphate and nicotine tartrate). 

Solution of Nicotine Sulphate, 5. Contains 40 0 per cent of the alkaloids of tobacco. 

Solution of Copper and Nicotine Sulphates, B. Vet.C. Contains 5 per cent w/v of copper sulphate and 5 per cent v/v of nicotine sulphate solution. 

Method 1. Reflux a mixture of pure nicotinic acid (Section V,22), 84 g. (105 ml.) of absolute ethanol and 90 g. (50 ml.) of concentrated sulphuric acid in a flask for 4 hours on a steam bath. Cool the solution and pour it slowly and with stirring on to 200 g. of crushed ice. Add sufficient ammonia solution to render the resulting solution strongly alkaline generally, some ester separates as an oil but most of it remains dissolved in the alkaline solution. Extract the solution with five 25 ml. portions of ether, dry the combined ethereal extracts with anhydrous magnesium sulphate, remove the ether and distil under reduced pressure. The ethyl nicotinate passes over at 117-118°/ 6 mm. the yield is 34 g. The b.p. under normal pressure is 222-224°. 

Inositol Nicotinate Terbutaline Sulphate Chlorhexidine Hydrochloride Naphazoline Hydrochloride Sulphadiazine Sulphasalazine Mepivacaine Hydrochloride Digitoxin... 

Diquat Dibromide Distigmine Bromide Ethyl Nicotinate Gallamine Triethiodide Hexamethonium Bromide Hydrastinine Mebezonium Iodide Neomycin Noradrenaline Paraquat Dichloride Pentolinium Tartrate Quinuronium Sulphate Streptomycin Tubocurarine Chloride... 

Hexonium bromide, 654 Hexonium iodide, 654 Hexopal, 683 Hexoprenaline, 658 Hexoprenaline hydrochloride, 658 Hexoprenaline sulphate, 658 Hexoral, 655 Hextril, 655 Hexyl nicotinate, 658 Hexylbenzenediol, 659... 

Neo-Mercazole carbimazole. neomycin [ban, inn] (neomycin suiphate Mycifradin ) is an (aminoglycoside) ANTIBIOTIC composed of a complex of neomycin A, B and C - early members of the aminoglycoside family produced by the mould Streptomyces fradiae. It has broad-spectrum antibacterial properties but is too toxic to be injected, though it can be used in treating some superficial bacterial infections, and is occasionally taken by mouth to reduce the levels of bacteria in the gut (it is not absorbed), neomycin B framycetin sulphate, neomycin sulphate neomycin, neopentanetetrayl nicotinate niceritrol. Neoral cyclosporine. 

The waste from tobacco Nicotiana tabacum production, family Solanacae, is used for the fabrication of raw nicotine, which also contains nor-nicotine and anabasine. Sulphates are made, and a solution is used as fumigant and insecticide. Nicotine must be handled with great care owing to the high toxicity (for humans) since 40 mg can be a lethal dose. 

In another letter to Lancet, doctors from Kelo University Hospital confirmed the somewhat unexpected domination of nicotinic signs and symptoms over the muscarinic ones (only one patient had mild bradycardia, 50 beats per minute) and questioned usefulness of treatment of mild cases of sarin intoxication with atropine sulphate eye drops, because of atropine-induced photophobia and poor focusing [25]. 

This is based on the reaction of derivatives of pyridine with cyanogen bromide in the presence of an aromatic amine giving specific colors. Amines commonly used are 2-naphthylamine-i-sulfonic acid, />-aminoacetophenone, iV-methyl-aminophenol sulphate, aniline and />-naphthylamine. The reaction gives a yellowish-green color which is measured photometrically. The color is soluble in amyl alcohol which can be used to extract it from water solutions, but is not stable unless a phosphate buffer of pH 6.i is used. This method is not specific for nicotinic acid since other pyridine derivatives and derivatives of nicotinic acid such as trigonelline, nicotinuric acid and nicotine give a similar color. 

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